Team Info
Houston Texans
NRG Stadium - Houston, TX
Owner Cal McNair
General Manager Nick Caserio
City Houston, TX
Stadium NRG Stadium
Head Coach DeMeco Ryans
Offensive Coordinator Nick Caley
Defensive Coordinator Matt Burke
Special Teams Coordinator Frank Ross
Starters
51
55
35
0
59
3
24
2
6
94
7
32
79
66
63
75
77
12
19
14
86
11 Personnel (Double Wing R) vs 4-3
Depth Chart
Injury Report
| 2009 | 1 | Eugene Wilson | CB | Knee | Out |
| 2009 | 1 | Jacques Reeves | CB | Fibula | Out |
| 2009 | 1 | Kevin Walter | WR | Hamstring | Questionable |
| 2009 | 1 | Deljuan Robinson | DT | Calf | Questionable |
| 2009 | 1 | Matt Schaub | QB | Ankle | Probable |
| 2009 | 2 | Antonio Smith | DE | Illness | — |
| 2009 | 2 | Andre Davis | WR | Concussion | Out |
| 2009 | 2 | Antwaun Molden | CB | Quadricep | Out |
| 2009 | 2 | Shaun Cody | DT | Knee | Questionable |
| 2009 | 2 | Jacques Reeves | CB | Fibula | Questionable |
| 2009 | 2 | Vonta Leach | RB | Knee | Questionable |
| 2009 | 2 | Kevin Walter | WR | Hamstring | Questionable |
| 2009 | 2 | Eugene Wilson | CB | Knee | Probable |
| 2009 | 3 | Chester Pitts | G | Knee | — |
| 2009 | 3 | Antwaun Molden | CB | Quadricep | Out |
| 2009 | 3 | Andre Davis | WR | Concussion | Doubtful |
| 2009 | 3 | Jacques Reeves | CB | Fibula | Doubtful |
| 2009 | 3 | Shaun Cody | DT | Knee | Questionable |
| 2009 | 3 | Kevin Walter | WR | Hamstring | Questionable |
| 2009 | 3 | Vonta Leach | RB | Knee | Probable |
| 2009 | 3 | Eugene Wilson | S | Knee | Probable |
| 2009 | 3 | Mike Brisiel | G | Shoulder | Probable |
| 2009 | 4 | Antwaun Molden | CB | Quadricep | Out |
| 2009 | 4 | Jacques Reeves | CB | Finger | Out |
| 2009 | 4 | Anthony Hill | TE | Illness | Doubtful |
| 2009 | 4 | Duane Brown | T | Illness | Questionable |
| 2009 | 4 | David Anderson | WR | Back | Questionable |
| 2009 | 4 | Chris Brown | RB | Shin | Questionable |
| 2009 | 4 | Joel Dreessen | TE | Hip | Questionable |
| 2009 | 4 | Shaun Cody | DT | Knee | Probable |
| 2009 | 4 | Brian Cushing | LB | Shoulder | Probable |
| 2009 | 4 | Andre Davis | WR | Concussion | Probable |
| 2009 | 4 | Amobi Okoye | DT | Back | Probable |
| 2009 | 5 | Fred Bennett | CB | Not Injury Related | — |
| 2009 | 5 | Nick Ferguson | S | Knee | Out |
| 2009 | 5 | Antwaun Molden | CB | Quadricep | Questionable |
| 2009 | 5 | James Casey | TE | Knee | Questionable |
| 2009 | 5 | Andre Davis | WR | Calf | Questionable |
| 2009 | 5 | Mario Williams | DE | Shoulder | Questionable |
| 2009 | 5 | Mike Brisiel | G | Shoulder | Probable |
| 2009 | 5 | John Busing | S | Groin | Probable |
| 2009 | 5 | Antoine Caldwell | G | Illness | Probable |
| 2009 | 5 | Brian Cushing | LB | Illness | Probable |
| 2009 | 5 | Anthony Hill | TE | Illness | Probable |
| 2009 | 5 | Ryan Moats | RB | Toe | Probable |
| 2009 | 5 | Jacques Reeves | CB | Finger | Probable |
| 2009 | 6 | James Casey | TE | Illness | — |
| 2009 | 6 | Rex Grossman | QB | Illness | — |
| 2009 | 6 | Nick Ferguson | S | Knee | Out |
| 2009 | 6 | Shaun Cody | DT | Illness | Questionable |
| 2009 | 6 | Brian Cushing | LB | Foot | Questionable |
| 2009 | 6 | Zach Diles | LB | Knee | Probable |
| 2009 | 6 | Mario Williams | DE | Shoulder | Probable |
| 2009 | 6 | DeMeco Ryans | LB | Shoulder | Probable |
| 2009 | 7 | Nick Ferguson | S | Knee | Out |
| 2009 | 7 | Jamie Winborn | LB | Calf | Doubtful |
| 2009 | 7 | Brian Cushing | LB | Foot | Questionable |
| 2009 | 7 | Mario Williams | DE | Shoulder | Questionable |
| 2009 | 7 | Kris Brown | K | right Ankle | Probable |
| 2009 | 7 | Bernard Pollard | S | Illness | Probable |
| 2009 | 7 | DeMeco Ryans | LB | Chest | Probable |
| 2009 | 8 | Jamie Winborn | LB | Calf | — |
| 2009 | 8 | James Casey | TE | Knee | Questionable |
| 2009 | 8 | Eugene Wilson | S | Groin | Questionable |
| 2009 | 8 | Tim Bulman | DE | Ribs | Questionable |
| 2009 | 8 | Brian Cushing | LB | Foot | Probable |
| 2009 | 8 | Nick Ferguson | S | Knee | Probable |
| 2009 | 8 | Andre Johnson | WR | Chest | Probable |
| 2009 | 8 | Antwaun Molden | CB | Hamstring | Probable |
| 2009 | 8 | Dunta Robinson | CB | Hamstring | Probable |
| 2009 | 8 | DeMeco Ryans | LB | Groin | Probable |
| 2009 | 8 | Chris White | G | Ankle | Probable |
| 2009 | 8 | Mario Williams | DE | Shoulder | Probable |
| 2009 | 9 | Glover Quin | CB | Not Injury Related | — |
| 2009 | 9 | Dominique Barber | S | Ankle | Out |
| 2009 | 9 | James Casey | TE | Knee | Out |
| 2009 | 9 | Shaun Cody | DT | Back | Questionable |
| 2009 | 9 | Deljuan Robinson | DT | Knee | Questionable |
| 2009 | 9 | Xavier Adibi | LB | Ankle | Probable |
| 2009 | 9 | Kevin Bentley | LB | Shoulder | Probable |
| 2009 | 9 | Tim Bulman | DE | Ribs | Probable |
| 2009 | 9 | Joel Dreessen | TE | Ankle | Probable |
| 2009 | 9 | Nick Ferguson | S | Knee | Probable |
| 2009 | 9 | Chris White | G | Ankle | Probable |
| 2009 | 9 | Brian Cushing | LB | Foot | Probable |
| 2009 | 9 | Mario Williams | DE | Shoulder | Probable |
| 2009 | 11 | Antwaun Molden | CB | Quadricep | Out |
| 2009 | 11 | Dominique Barber | S | Ankle | Doubtful |
| 2009 | 11 | Jacoby Jones | WR | Calf | Questionable |
| 2009 | 11 | James Casey | TE | Knee | Probable |
| 2009 | 11 | Brian Cushing | LB | Foot | Probable |
| 2009 | 12 | Antwaun Molden | CB | Quadricep | — |
| 2009 | 12 | Amobi Okoye | DT | Illness | Questionable |
| 2009 | 12 | Dominique Barber | S | Ankle | Questionable |
| 2009 | 12 | DeMeco Ryans | LB | Ankle | Questionable |
| 2009 | 12 | Brian Cushing | LB | Foot | Probable |
| 2009 | 12 | Joel Dreessen | TE | Shoulder | Probable |
| 2009 | 12 | Jacoby Jones | WR | Calf | Probable |
| 2009 | 12 | Steve Slaton | RB | Neck | Probable |
| 2009 | 13 | Glover Quin | CB | Head | Out |
| 2009 | 13 | Steve Slaton | RB | Neck | Questionable |
| 2009 | 13 | Duane Brown | T | Knee | Questionable |
| 2009 | 13 | Xavier Adibi | LB | Illness | Probable |
| 2009 | 13 | Brian Cushing | LB | Foot | Probable |
| 2009 | 13 | Zach Diles | LB | Illness | Probable |
| 2009 | 13 | DeMeco Ryans | LB | Ankle | Probable |
| 2009 | 14 | Jeff Zgonina | DT | Not Injury Related | — |
| 2009 | 14 | Tim Bulman | DE | Hamstring | Out |
| 2009 | 14 | Mario Williams | DE | Groin | Questionable |
| 2009 | 14 | Duane Brown | T | Knee | Probable |
| 2009 | 14 | Brian Cushing | LB | Foot | Probable |
| 2009 | 14 | Glover Quin | CB | Head | Probable |
| 2009 | 14 | Matt Schaub | QB | left Shoulder | Probable |
| 2009 | 15 | Chris Myers | C | Ribs | Questionable |
| 2009 | 15 | Tim Bulman | DE | Hamstring | Probable |
| 2009 | 15 | Brian Cushing | LB | Foot | Probable |
| 2009 | 15 | Joel Dreessen | TE | Shoulder | Probable |
| 2009 | 15 | Arian Foster | RB | Ribs | Probable |
| 2009 | 15 | Vonta Leach | RB | Illness | Probable |
| 2009 | 15 | Matt Schaub | QB | left Shoulder | Probable |
| 2009 | 15 | Kasey Studdard | G | Ankle | Probable |
| 2009 | 15 | Mario Williams | DE | Groin | Probable |
| 2009 | 15 | Duane Brown | T | Knee | Probable |
| 2009 | 16 | Brian Cushing | LB | Foot / Ribs | Questionable |
| 2009 | 16 | Duane Brown | T | Knee | Questionable |
| 2009 | 16 | Andre Davis | WR | Finger | Questionable |
| 2009 | 16 | Joel Dreessen | TE | Shoulder | Probable |
| 2009 | 17 | Brian Cushing | LB | Foot / Ribs | Questionable |
| 2009 | 17 | Shaun Cody | DT | Knee | Questionable |
| 2009 | 17 | Joel Dreessen | TE | Shoulder | Probable |
| 2009 | 17 | Andre Johnson | WR | Ankle | Probable |
| 2009 | 17 | Jacoby Jones | WR | Shoulder | Probable |
| 2009 | 17 | Duane Brown | T | Knee | Probable |
| 2010 | 1 | Antwaun Molden | CB | Ankle | Doubtful |
| 2010 | 1 | Kareem Jackson | CB | Eye | Probable |
| 2010 | 1 | Steve Slaton | RB | Toe | Probable |
| 2010 | 1 | Duane Brown | T | Hamstring | Probable |
| 2010 | 1 | Owen Daniels | TE | Knee | Probable |
| 2010 | 1 | Mario Williams | DE | Groin | Probable |
| 2010 | 2 | Antwaun Molden | CB | Ankle | Questionable |
| 2010 | 2 | Amobi Okoye | DT | Ankle | Questionable |
| 2010 | 2 | Dominique Barber | S | Shoulder | Probable |
| 2010 | 2 | Duane Brown | T | Hamstring | Probable |
| 2010 | 2 | Vonta Leach | RB | Neck | Probable |
| 2010 | 2 | Neil Rackers | K | Illness | Probable |
| 2010 | 2 | Antonio Smith | DE | Back | Probable |
| 2010 | 2 | Kevin Walter | WR | Hip | Probable |
| 2010 | 2 | Mario Williams | DE | Groin | Probable |
| 2010 | 2 | Eugene Wilson | S | Back | Probable |
| 2010 | 2 | Owen Daniels | TE | Knee | Probable |
| 2010 | 3 | Andre Johnson | WR | Ankle | Questionable |
| 2010 | 3 | James Casey | TE | Ankle | Probable |
| 2010 | 3 | Joel Dreessen | TE | Hip | Probable |
| 2010 | 3 | Vonta Leach | RB | Knee | Probable |
| 2010 | 3 | Antwaun Molden | CB | Ankle | Probable |
| 2010 | 3 | Owen Daniels | TE | Knee | Probable |
| 2010 | 3 | Amobi Okoye | DT | Ankle | Probable |
| 2010 | 3 | Mario Williams | DE | Groin | Probable |
| 2010 | 4 | Kevin Bentley | LB | Knee | Out |
| 2010 | 4 | Eugene Wilson | S | Hamstring | Doubtful |
| 2010 | 4 | Owen Daniels | TE | Hamstring | Questionable |
| 2010 | 4 | Andre Johnson | WR | Ankle | Questionable |
| 2010 | 4 | Darryl Sharpton | WR | Ankle | Questionable |
| 2010 | 4 | Xavier Adibi | LB | Hamstring | Probable |
| 2010 | 4 | DeMeco Ryans | LB | Quadricep | Probable |
| 2010 | 4 | Mario Williams | DE | Groin | Probable |
| 2010 | 5 | Kevin Bentley | LB | Knee | Out |
| 2010 | 5 | Jacoby Jones | WR | Calf | Doubtful |
| 2010 | 5 | Andre Johnson | WR | Ankle | Questionable |
| 2010 | 5 | Derrick Ward | RB | Ribs | Questionable |
| 2010 | 5 | Mario Williams | DE | Groin | Questionable |
| 2010 | 5 | Jesse Nading | DE | Knee | Probable |
| 2010 | 5 | Darryl Sharpton | LB | Ankle | Probable |
| 2010 | 5 | Dominique Barber | S | Ribs | Probable |
| 2010 | 5 | Owen Daniels | TE | Hamstring | Probable |
| 2010 | 5 | Bernard Pollard | S | Neck | Probable |
| 2010 | 5 | Eugene Wilson | S | Hamstring | Probable |
| 2010 | 6 | Jesse Nading | DE | Knee | Out |
| 2010 | 6 | Xavier Adibi | LB | Hamstring | Doubtful |
| 2010 | 6 | Kevin Bentley | LB | Knee | Doubtful |
| 2010 | 6 | Mike Brisiel | G | Knee | Doubtful |
| 2010 | 6 | Sherrick McManis | CB | Hamstring | Doubtful |
| 2010 | 6 | Dorin Dickerson | WR | Knee | Questionable |
| 2010 | 6 | Jacoby Jones | WR | Calf | Questionable |
| 2010 | 6 | Mario Williams | DE | Shoulder | Questionable |
| 2010 | 6 | Dominique Barber | S | Ribs | Probable |
| 2010 | 6 | Brian Cushing | LB | Knee | Probable |
| 2010 | 6 | Owen Daniels | TE | Hamstring | Probable |
| 2010 | 6 | Arian Foster | RB | Knee | Probable |
| 2010 | 6 | Bernard Pollard | S | Neck | Probable |
| 2010 | 6 | DeMeco Ryans | LB | Groin | Probable |
| 2010 | 6 | Darryl Sharpton | LB | Ankle | Probable |
| 2010 | 6 | Derrick Ward | RB | Ribs | Probable |
| 2010 | 6 | Andre Johnson | WR | Ankle | Probable |
| 2010 | 8 | Steve Slaton | RB | Not Injury Related | — |
| 2010 | 8 | Earl Mitchell | DT | Ankle | Doubtful |
| 2010 | 8 | Jesse Nading | DE | Knee | Doubtful |
| 2010 | 8 | Mike Brisiel | G | Knee | Questionable |
| 2010 | 8 | Xavier Adibi | LB | Hamstring | Probable |
| 2010 | 8 | Owen Daniels | TE | Knee | Probable |
| 2010 | 8 | Dorin Dickerson | WR | Knee | Probable |
| 2010 | 8 | Garrett Graham | TE | Shoulder | Probable |
| 2010 | 8 | Andre Johnson | WR | Ankle | Probable |
| 2010 | 8 | Sherrick McManis | CB | Hamstring | Probable |
| 2010 | 8 | Karl Paymah | CB | Wrist | Probable |
| 2010 | 8 | Darryl Sharpton | LB | Ankle | Probable |
| 2010 | 8 | Kevin Bentley | LB | Knee | Probable |
| 2010 | 9 | Xavier Adibi | LB | Hamstring | Questionable |
| 2010 | 9 | Shaun Cody | DT | Knee | Questionable |
| 2010 | 9 | Owen Daniels | TE | Hamstring | Questionable |
| 2010 | 9 | Jesse Nading | DE | Ankle | Questionable |
| 2010 | 9 | Earl Mitchell | DT | Ankle | Questionable |
| 2010 | 9 | Kevin Bentley | LB | Knee | Probable |
| 2010 | 9 | Mike Brisiel | G | Knee | Probable |
| 2010 | 9 | Garrett Graham | TE | Shoulder | Probable |
| 2010 | 9 | Stanford Keglar | LB | Thigh | Probable |
| 2010 | 9 | Karl Paymah | CB | Wrist | Probable |
| 2010 | 9 | Darryl Sharpton | LB | Ankle | Probable |
| 2010 | 9 | Andre Johnson | WR | Ankle | Probable |
| 2010 | 9 | Mario Williams | DE | Hip | Probable |
| 2010 | 10 | Dominique Barber | S | Knee | — |
| 2010 | 10 | Owen Daniels | TE | Hamstring | Out |
| 2010 | 10 | Xavier Adibi | LB | Hamstring | Doubtful |
| 2010 | 10 | Glover Quin | CB | Neck | Questionable |
| 2010 | 10 | Andre Johnson | WR | Ankle | Questionable |
| 2010 | 10 | Jesse Nading | DE | Knee | Questionable |
| 2010 | 10 | Mark Anderson | DE | Arm | Probable |
| 2010 | 10 | Kevin Bentley | LB | Knee | Probable |
| 2010 | 10 | Mike Brisiel | G | Back | Probable |
| 2010 | 10 | Garrett Graham | TE | Shoulder | Probable |
| 2010 | 10 | Stanford Keglar | LB | Thigh | Probable |
| 2010 | 10 | Earl Mitchell | DT | Ankle | Probable |
| 2010 | 10 | Karl Paymah | CB | Wrist | Probable |
| 2010 | 10 | Matt Schaub | QB | Ribs | Probable |
| 2010 | 10 | Mario Williams | DE | Groin | Probable |
| 2010 | 10 | Shaun Cody | DT | Knee | Probable |
| 2010 | 11 | Owen Daniels | TE | Hamstring | Out |
| 2010 | 11 | Jesse Nading | DE | Knee | Out |
| 2010 | 11 | Zach Diles | LB | Illness | Questionable |
| 2010 | 11 | Xavier Adibi | LB | Hamstring | Questionable |
| 2010 | 11 | Matt Schaub | QB | Knee | Questionable |
| 2010 | 11 | Arian Foster | RB | Not Injury Related | Probable |
| 2010 | 11 | Mark Anderson | DE | Arm | Probable |
| 2010 | 11 | Kevin Bentley | LB | Knee | Probable |
| 2010 | 11 | Mike Brisiel | G | Knee / Ribs | Probable |
| 2010 | 11 | Shaun Cody | DT | Knee | Probable |
| 2010 | 11 | Kareem Jackson | CB | Shin | Probable |
| 2010 | 11 | Stanford Keglar | LB | Quadricep | Probable |
| 2010 | 11 | Kevin Walter | WR | Knee | Probable |
| 2010 | 11 | Andre Johnson | WR | Ankle | Probable |
| 2010 | 11 | Chris Myers | C | Shoulder | Probable |
| 2010 | 11 | Matt Turk | P | right Hip | Probable |
| 2010 | 11 | Mario Williams | DE | Groin | Probable |
| 2010 | 12 | Xavier Adibi | LB | Hamstring | Out |
| 2010 | 12 | Owen Daniels | TE | Hamstring | Out |
| 2010 | 12 | Jesse Nading | DE | Knee | Out |
| 2010 | 12 | David Anderson | WR | Hamstring | Questionable |
| 2010 | 12 | Shaun Cody | DT | Illness | Questionable |
| 2010 | 12 | Kevin Bentley | LB | Shoulder / Knee | Probable |
| 2010 | 12 | Zach Diles | LB | Illness | Probable |
| 2010 | 12 | Andre Johnson | WR | Ankle | Probable |
| 2010 | 12 | Glover Quin | CB | Hand | Probable |
| 2010 | 12 | Matt Schaub | QB | Knee | Probable |
| 2010 | 12 | Jonathan Weeks | LS | Knee | Probable |
| 2010 | 12 | Brian Cushing | LB | Knee | Probable |
| 2010 | 12 | Mario Williams | DE | Groin | Probable |
| 2010 | 13 | Torri Williams | S | Hamstring | — |
| 2010 | 13 | Xavier Adibi | LB | Hamstring | Out |
| 2010 | 13 | Owen Daniels | TE | Hamstring | Out |
| 2010 | 13 | Jesse Nading | DE | Knee | Questionable |
| 2010 | 13 | David Anderson | WR | Hamstring | Questionable |
| 2010 | 13 | Kevin Walter | WR | Calf | Questionable |
| 2010 | 13 | Kevin Bentley | LB | Knee / Shoulder | Probable |
| 2010 | 13 | Joel Dreessen | TE | Knee | Probable |
| 2010 | 13 | Jacoby Jones | WR | Illness | Probable |
| 2010 | 13 | Glover Quin | CB | Hand | Probable |
| 2010 | 13 | Matt Schaub | QB | Knee | Probable |
| 2010 | 13 | Eric Winston | T | Shoulder | Probable |
| 2010 | 13 | Brian Cushing | LB | Knee | Probable |
| 2010 | 13 | Mario Williams | DE | Groin | Probable |
| 2010 | 14 | Garrett Graham | TE | Hamstring | Out |
| 2010 | 14 | Xavier Adibi | LB | Hamstring | Probable |
| 2010 | 14 | Mike Brisiel | G | Shoulder | Probable |
| 2010 | 14 | Owen Daniels | TE | Hamstring | Probable |
| 2010 | 14 | Joel Dreessen | TE | Ribs | Probable |
| 2010 | 14 | Glover Quin | CB | Hand | Probable |
| 2010 | 14 | Matt Schaub | QB | Knee | Probable |
| 2010 | 14 | Eric Winston | T | Shoulder | Probable |
| 2010 | 14 | Brian Cushing | LB | Knee | Probable |
| 2010 | 14 | Andre Johnson | WR | Ankle | Probable |
| 2010 | 14 | Mario Williams | DE | Groin | Probable |
| 2010 | 15 | Garrett Graham | TE | Hamstring | Out |
| 2010 | 15 | Xavier Adibi | LB | Hamstring | Probable |
| 2010 | 15 | Owen Daniels | TE | Hamstring | Probable |
| 2010 | 15 | Joel Dreessen | TE | Hand | Probable |
| 2010 | 15 | Glover Quin | CB | Hand | Probable |
| 2010 | 15 | Matt Schaub | QB | L. Arm | Probable |
| 2010 | 15 | Darryl Sharpton | LB | Neck | Probable |
| 2010 | 15 | Kevin Walter | WR | Knee | Probable |
| 2010 | 15 | Eric Winston | T | Shoulder | Probable |
| 2010 | 15 | Brian Cushing | LB | Knee / Finger and Neck | Probable |
| 2010 | 15 | Arian Foster | RB | Hip | Probable |
| 2010 | 15 | Andre Johnson | WR | Ankle | Probable |
| 2010 | 15 | Neil Rackers | K | right Hamstring | Probable |
| 2010 | 16 | Garrett Graham | TE | Hamstring | Out |
| 2010 | 16 | Andre Johnson | WR | Ankle | Questionable |
| 2010 | 16 | Damione Lewis | DT | Illness | Probable |
| 2010 | 16 | Neil Rackers | K | right Hamstring | Probable |
| 2010 | 16 | Mark Anderson | DE | Knee | Probable |
| 2010 | 16 | Duane Brown | T | Shoulder | Probable |
| 2010 | 16 | Arian Foster | RB | Hip | Probable |
| 2010 | 16 | Matt Schaub | QB | right Elbow | Probable |
| 2010 | 16 | Brian Cushing | LB | Knee / Ankle and Foot | Probable |
| 2010 | 17 | Darryl Sharpton | LB | Shoulder | — |
| 2010 | 17 | Sherrick McManis | CB | Hamstring | Out |
| 2010 | 17 | Andre Johnson | WR | Ankle | Doubtful |
| 2010 | 17 | Garrett Graham | TE | Hamstring | Doubtful |
| 2010 | 17 | Shaun Cody | DT | Knee | Questionable |
| 2010 | 17 | Earl Mitchell | DT | Ankle | Questionable |
| 2010 | 17 | Bernard Pollard | S | Shoulder | Questionable |
| 2010 | 17 | Neil Rackers | K | right Hamstring | Probable |
| 2010 | 17 | Antoine Caldwell | G | Shoulder | Probable |
| 2010 | 17 | Owen Daniels | TE | Knee | Probable |
| 2010 | 17 | Brian Cushing | LB | Knee / Foot | Probable |
| 2011 | 1 | Rashad Carmichael | CB | Shoulder | Out |
| 2011 | 1 | Arian Foster | RB | Hamstring | Questionable |
| 2011 | 1 | Antoine Caldwell | G | Ankle | Probable |
| 2011 | 1 | Earl Mitchell | DT | Knee | Probable |
| 2011 | 1 | Glover Quin | CB | Head | Probable |
| 2011 | 1 | Brooks Reed | LB | Wrist | Probable |
| 2011 | 1 | DeMeco Ryans | LB | Elbow / Ankle | Probable |
| 2011 | 1 | Jonathan Weeks | LS | Ankle | Probable |
| 2011 | 1 | Mario Williams | LB | Groin / Achilles | Probable |
| 2011 | 2 | Derrick Ward | RB | Ankle / Shoulder | Out |
| 2011 | 2 | Rashad Carmichael | CB | Shoulder | Out |
| 2011 | 2 | Kevin Walter | WR | Shoulder / Quadricep | Questionable |
| 2011 | 2 | Arian Foster | RB | Hamstring | Questionable |
| 2011 | 2 | Sherrick McManis | CB | Hamstring | Questionable |
| 2011 | 2 | Jason Allen | CB | Knee | Probable |
| 2011 | 2 | Thomas Austin | G | Knee | Probable |
| 2011 | 2 | Antoine Caldwell | G | Ankle | Probable |
| 2011 | 2 | Shaun Cody | DT | Neck | Probable |
| 2011 | 2 | Brian Cushing | LB | Foot | Probable |
| 2011 | 2 | Brandon Harris | CB | Ankle | Probable |
| 2011 | 2 | Brooks Reed | LB | Wrist | Probable |
| 2011 | 2 | DeMeco Ryans | LB | Elbow / Achilles | Probable |
| 2011 | 2 | Antonio Smith | DE | Groin | Probable |
| 2011 | 2 | Ben Tate | RB | Quadricep | Probable |
| 2011 | 2 | Mario Williams | LB | Elbow | Probable |
| 2011 | 3 | Sherrick McManis | CB | Hamstring | Out |
| 2011 | 3 | Derrick Ward | RB | Shoulder / Ankle | Out |
| 2011 | 3 | Rashad Butler | T | Elbow | Out |
| 2011 | 3 | Arian Foster | RB | Hamstring | Questionable |
| 2011 | 3 | Jacoby Jones | WR | Knee | Questionable |
| 2011 | 3 | Thomas Austin | G | Knee | Probable |
| 2011 | 3 | Mike Brisiel | G | Hip | Probable |
| 2011 | 3 | Brian Cushing | LB | Knee | Probable |
| 2011 | 3 | Johnathan Joseph | CB | Ankle | Probable |
| 2011 | 3 | DeMeco Ryans | LB | Elbow / Achilles | Probable |
| 2011 | 3 | Matt Schaub | QB | Foot | Probable |
| 2011 | 3 | Ben Tate | RB | Back | Probable |
| 2011 | 3 | Mario Williams | LB | Thumb | Probable |
| 2011 | 3 | Kevin Walter | WR | Shoulder / Thigh | Probable |
| 2011 | 4 | Derrick Ward | RB | Ankle / Shoulder | Out |
| 2011 | 4 | Sherrick McManis | CB | Hamstring | Doubtful |
| 2011 | 4 | Kareem Jackson | CB | Knee | Questionable |
| 2011 | 4 | Thomas Austin | G | Knee | Probable |
| 2011 | 4 | Bryan Braman | LB | Wrist | Probable |
| 2011 | 4 | Mike Brisiel | G | Shoulder | Probable |
| 2011 | 4 | Arian Foster | RB | Hamstring | Probable |
| 2011 | 4 | Johnathan Joseph | CB | Foot | Probable |
| 2011 | 4 | DeMeco Ryans | LB | Knee / Elbow | Probable |
| 2011 | 4 | Ben Tate | RB | Back / Hip | Probable |
| 2011 | 4 | Lawrence Vickers | RB | Illness | Probable |
| 2011 | 4 | Joel Dreessen | TE | Knee | Probable |
| 2011 | 4 | Andre Johnson | WR | Knee / Toe | Probable |
| 2011 | 4 | Jacoby Jones | WR | Knee | Probable |
| 2011 | 4 | Kevin Walter | WR | Shoulder | Probable |
| 2011 | 4 | Mario Williams | LB | Knee | Probable |
| 2011 | 5 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 5 | Tim Dobbins | LB | Hamstring | Doubtful |
| 2011 | 5 | Bryant Johnson | WR | Hamstring | Questionable |
| 2011 | 5 | Sherrick McManis | CB | Hamstring | Questionable |
| 2011 | 5 | Kareem Jackson | CB | Knee | Questionable |
| 2011 | 5 | DeMeco Ryans | LB | Elbow / Hamstring | Questionable |
| 2011 | 5 | Ben Tate | RB | Groin | Questionable |
| 2011 | 5 | Derrick Ward | RB | Ankle / Shoulder | Questionable |
| 2011 | 5 | Jason Allen | CB | Knee | Probable |
| 2011 | 5 | Thomas Austin | G | Knee | Probable |
| 2011 | 5 | Arian Foster | RB | Hip | Probable |
| 2011 | 5 | Jacoby Jones | WR | Knee | Probable |
| 2011 | 5 | Johnathan Joseph | CB | Hamstring | Probable |
| 2011 | 5 | Brice McCain | CB | Groin | Probable |
| 2011 | 5 | Chris Myers | C | Elbow / Ankle | Probable |
| 2011 | 5 | Antonio Smith | DE | Ankle | Probable |
| 2011 | 5 | Mario Williams | LB | Elbow | Probable |
| 2011 | 6 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 6 | James Casey | RB | Chest | Doubtful |
| 2011 | 6 | Jason Allen | CB | Knee / Groin | Probable |
| 2011 | 6 | Thomas Austin | G | Knee | Probable |
| 2011 | 6 | Mike Brisiel | G | Ankle / Knee | Probable |
| 2011 | 6 | Tim Dobbins | LB | Hamstring | Probable |
| 2011 | 6 | Joel Dreessen | TE | Hip | Probable |
| 2011 | 6 | Garrett Graham | TE | Hamstring | Probable |
| 2011 | 6 | Brandon Harris | CB | Hamstring | Probable |
| 2011 | 6 | Kareem Jackson | CB | Knee | Probable |
| 2011 | 6 | Jacoby Jones | WR | Knee | Probable |
| 2011 | 6 | Johnathan Joseph | CB | Calf | Probable |
| 2011 | 6 | Brice McCain | CB | Hamstring / Concussion | Probable |
| 2011 | 6 | Sherrick McManis | CB | Hamstring | Probable |
| 2011 | 6 | Antonio Smith | DE | Ankle | Probable |
| 2011 | 6 | Ben Tate | RB | Groin / Achilles | Probable |
| 2011 | 6 | Kevin Walter | WR | Illness | Probable |
| 2011 | 6 | Derrick Ward | RB | Ankle | Probable |
| 2011 | 6 | Arian Foster | RB | Quadricep | Probable |
| 2011 | 6 | Bryant Johnson | WR | Hamstring | Probable |
| 2011 | 6 | DeMeco Ryans | LB | Elbow / Hamstring/Knee | Probable |
| 2011 | 6 | Matt Schaub | QB | right Shoulder | Probable |
| 2011 | 7 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 7 | James Casey | RB | Chest | Doubtful |
| 2011 | 7 | Antoine Caldwell | G | Ankle | Questionable |
| 2011 | 7 | Duane Brown | T | Knee | Probable |
| 2011 | 7 | Brian Cushing | LB | Elbow | Probable |
| 2011 | 7 | Johnathan Joseph | CB | Shoulder | Probable |
| 2011 | 7 | Matt Leinart | QB | left Thumb | Probable |
| 2011 | 7 | Matt Schaub | QB | Chest / Hip | Probable |
| 2011 | 7 | Darryl Sharpton | LB | Back / Groin | Probable |
| 2011 | 7 | Mike Brisiel | G | Shin | Probable |
| 2011 | 7 | Jacoby Jones | WR | Groin | Probable |
| 2011 | 7 | Danieal Manning | S | Fibula | Probable |
| 2011 | 7 | DeMeco Ryans | LB | Hamstring | Probable |
| 2011 | 8 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 8 | Danieal Manning | S | Ankle | Out |
| 2011 | 8 | Thomas Austin | G | Knee | Probable |
| 2011 | 8 | Bryan Braman | LB | Neck | Probable |
| 2011 | 8 | Mike Brisiel | G | Leg | Probable |
| 2011 | 8 | Tim Bulman | DE | Elbow | Probable |
| 2011 | 8 | Antoine Caldwell | G | Ankle | Probable |
| 2011 | 8 | Brian Cushing | LB | Illness | Probable |
| 2011 | 8 | Johnathan Joseph | CB | Neck / Ankle | Probable |
| 2011 | 8 | Chris Myers | C | Knee | Probable |
| 2011 | 8 | DeMeco Ryans | LB | Elbow / Hamstring | Probable |
| 2011 | 8 | Kevin Walter | WR | Knee | Probable |
| 2011 | 8 | Eric Winston | T | Ankle | Probable |
| 2011 | 8 | James Casey | RB | Chest | Probable |
| 2011 | 9 | Derrick Mason | WR | Finger | — |
| 2011 | 9 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 9 | Danieal Manning | S | Ankle | Out |
| 2011 | 9 | Jason Allen | CB | Knee | Probable |
| 2011 | 9 | Thomas Austin | G | Knee | Probable |
| 2011 | 9 | Bryan Braman | LB | Neck | Probable |
| 2011 | 9 | Mike Brisiel | G | Shin | Probable |
| 2011 | 9 | Duane Brown | T | Shoulder | Probable |
| 2011 | 9 | Antoine Caldwell | G | Ankle | Probable |
| 2011 | 9 | Brian Cushing | LB | Knee | Probable |
| 2011 | 9 | Sherrick McManis | CB | Groin | Probable |
| 2011 | 9 | Chris Myers | C | Knee | Probable |
| 2011 | 9 | DeMeco Ryans | LB | Elbow / Hamstring/Wrist | Probable |
| 2011 | 9 | Ben Tate | RB | Ankle | Probable |
| 2011 | 9 | Eric Winston | T | Ankle | Probable |
| 2011 | 9 | Connor Barwin | LB | Achilles | Probable |
| 2011 | 9 | James Casey | RB | Chest | Probable |
| 2011 | 9 | Kevin Walter | WR | Knee | Probable |
| 2011 | 10 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 10 | Danieal Manning | S | Ankle | Out |
| 2011 | 10 | Sherrick McManis | CB | Groin | Questionable |
| 2011 | 10 | Earl Mitchell | DT | Ankle | Questionable |
| 2011 | 10 | Antonio Smith | DE | Shoulder | Questionable |
| 2011 | 10 | Eric Winston | T | Back | Questionable |
| 2011 | 10 | Mister Alexander | LB | Shoulder | Probable |
| 2011 | 10 | Jason Allen | CB | Knee | Probable |
| 2011 | 10 | Thomas Austin | G | Knee | Probable |
| 2011 | 10 | Connor Barwin | LB | Achilles | Probable |
| 2011 | 10 | Bryan Braman | LB | Thigh | Probable |
| 2011 | 10 | Mike Brisiel | G | Back | Probable |
| 2011 | 10 | Duane Brown | T | Shoulder | Probable |
| 2011 | 10 | Antoine Caldwell | G | Ankle | Probable |
| 2011 | 10 | James Casey | RB | Pectoral | Probable |
| 2011 | 10 | Shaun Cody | DT | Back | Probable |
| 2011 | 10 | Brian Cushing | LB | Knee / Hamstring | Probable |
| 2011 | 10 | Tim Dobbins | LB | Hip | Probable |
| 2011 | 10 | Johnathan Joseph | CB | Hamstring / Abdomen | Probable |
| 2011 | 10 | Jesse Nading | LB | Shoulder | Probable |
| 2011 | 10 | Wade Smith | G | Ankle | Probable |
| 2011 | 10 | Ben Tate | RB | Foot / Ankle | Probable |
| 2011 | 10 | Kevin Walter | WR | Knee / Ankle | Probable |
| 2011 | 12 | Garrett Graham | TE | Hamstring | Doubtful |
| 2011 | 12 | Tim Bulman | DE | Calf | Questionable |
| 2011 | 12 | Lawrence Vickers | RB | Hamstring | Questionable |
| 2011 | 12 | Jason Allen | CB | Knee | Probable |
| 2011 | 12 | Bryan Braman | LB | Thigh | Probable |
| 2011 | 12 | James Casey | RB | Chest | Probable |
| 2011 | 12 | Owen Daniels | TE | Knee | Probable |
| 2011 | 12 | Tim Dobbins | LB | Hamstring | Probable |
| 2011 | 12 | Andre Johnson | WR | Hamstring | Probable |
| 2011 | 12 | Earl Mitchell | DT | Ankle | Probable |
| 2011 | 12 | Jesse Nading | DE | Shoulder / Hip | Probable |
| 2011 | 12 | DeMeco Ryans | LB | Shoulder | Probable |
| 2011 | 12 | Mister Alexander | LB | Shoulders | Probable |
| 2011 | 12 | Danieal Manning | S | Ankle | Probable |
| 2011 | 12 | Antonio Smith | DE | Shoulder | Probable |
| 2011 | 13 | Tim Bulman | DE | Calf | Out |
| 2011 | 13 | Lawrence Vickers | RB | Hamstring | Questionable |
| 2011 | 13 | Garrett Graham | TE | Hamstring | Questionable |
| 2011 | 13 | Mister Alexander | LB | Shoulder | Probable |
| 2011 | 13 | Jason Allen | CB | Thumb | Probable |
| 2011 | 13 | Mike Brisiel | G | Ankle | Probable |
| 2011 | 13 | Shaun Cody | DT | Toe / Ankle | Probable |
| 2011 | 13 | Owen Daniels | TE | Knee | Probable |
| 2011 | 13 | Tim Dobbins | LB | Shoulder | Probable |
| 2011 | 13 | Joel Dreessen | TE | Neck | Probable |
| 2011 | 13 | Johnathan Joseph | CB | Hip | Probable |
| 2011 | 13 | Danieal Manning | S | Ankle | Probable |
| 2011 | 13 | Glover Quin | S | Elbow | Probable |
| 2011 | 13 | Wade Smith | G | Ankle | Probable |
| 2011 | 13 | Antonio Smith | DE | Shoulder / Back | Probable |
| 2011 | 13 | J.J. Watt | DE | Knee / Thigh | Probable |
| 2011 | 13 | Brian Cushing | LB | Ribs | Probable |
| 2011 | 13 | Andre Johnson | WR | Knee | Probable |
| 2011 | 14 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 14 | Tim Bulman | DE | Calf | Questionable |
| 2011 | 14 | Kevin Walter | WR | Illness | Questionable |
| 2011 | 14 | Lawrence Vickers | RB | Hamstring | Questionable |
| 2011 | 14 | Mister Alexander | LB | Shoulder | Probable |
| 2011 | 14 | Jason Allen | CB | Thumb / Head | Probable |
| 2011 | 14 | James Casey | RB | Chest | Probable |
| 2011 | 14 | Brian Cushing | LB | Ribs / Knee | Probable |
| 2011 | 14 | Jake Delhomme | QB | Calf | Probable |
| 2011 | 14 | Joel Dreessen | TE | Groin | Probable |
| 2011 | 14 | Garrett Graham | TE | Hamstring | Probable |
| 2011 | 14 | Brandon Harris | CB | Hip | Probable |
| 2011 | 14 | Brice McCain | CB | Shoulder | Probable |
| 2011 | 14 | Glover Quin | S | Elbow / Knee | Probable |
| 2011 | 14 | Antonio Smith | DE | Shoulder | Probable |
| 2011 | 14 | Eric Winston | T | Knee | Probable |
| 2011 | 14 | Mike Brisiel | G | Ankle | Probable |
| 2011 | 15 | Glover Quin | S | Not Injury Related | — |
| 2011 | 15 | Mike Brisiel | G | Ankle | Out |
| 2011 | 15 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 15 | Sherrick McManis | CB | Ankle | Out |
| 2011 | 15 | Tim Bulman | DE | Calf | Questionable |
| 2011 | 15 | Shaun Cody | DT | Knee | Questionable |
| 2011 | 15 | Joel Dreessen | TE | Knee | Questionable |
| 2011 | 15 | Mister Alexander | LB | Shoulder | Probable |
| 2011 | 15 | Jason Allen | CB | Thumb | Probable |
| 2011 | 15 | Garrett Graham | TE | Hamstring | Probable |
| 2011 | 15 | Brandon Harris | CB | Hip | Probable |
| 2011 | 15 | Jesse Nading | DE | Knee | Probable |
| 2011 | 15 | Lawrence Vickers | RB | Hamstring | Probable |
| 2011 | 15 | J.J. Watt | DE | Hand | Probable |
| 2011 | 15 | T.J. Yates | QB | right Elbow / L. Hand/Hip | Probable |
| 2011 | 15 | Chris Myers | C | Knee | Probable |
| 2011 | 15 | Kevin Walter | WR | Knee | Probable |
| 2011 | 16 | Mike Brisiel | G | Ankle | Out |
| 2011 | 16 | Andre Johnson | WR | Hamstring | Out |
| 2011 | 16 | Sherrick McManis | CB | Ankle | Out |
| 2011 | 16 | Troy Nolan | S | Ankle | Out |
| 2011 | 16 | Shaun Cody | DT | Knee | Questionable |
| 2011 | 16 | Owen Daniels | TE | Knee | Questionable |
| 2011 | 16 | Mister Alexander | LB | Shoulder | Probable |
| 2011 | 16 | Jason Allen | CB | Thumb | Probable |
| 2011 | 16 | Tim Bulman | DE | Calf | Probable |
| 2011 | 16 | Antoine Caldwell | G | Ankle | Probable |
| 2011 | 16 | James Casey | RB | Foot | Probable |
| 2011 | 16 | Brandon Harris | CB | Hip | Probable |
| 2011 | 16 | Tim Jamison | DE | Knee | Probable |
| 2011 | 16 | Jeff Maehl | WR | Hamstring | Probable |
| 2011 | 16 | Earl Mitchell | DT | Knee | Probable |
| 2011 | 16 | Chris Myers | C | Knee | Probable |
| 2011 | 16 | Jesse Nading | LB | Knee | Probable |
| 2011 | 16 | Glover Quin | S | Ankle | Probable |
| 2011 | 16 | Neil Rackers | K | right Calf | Probable |
| 2011 | 16 | Kevin Walter | WR | Quadricep | Probable |
| 2011 | 16 | Joel Dreessen | TE | Knee / Wrist | Probable |
| 2011 | 16 | Jacoby Jones | WR | Foot | Probable |
| 2011 | 16 | Johnathan Joseph | CB | Hamstring | Probable |
| 2011 | 16 | Antonio Smith | DE | Ankle | Probable |
| 2011 | 16 | Ben Tate | RB | Hamstring | Probable |
| 2011 | 16 | T.J. Yates | QB | right Shoulder | Probable |
| 2011 | 17 | Johnathan Joseph | CB | Not Injury Related | — |
| 2011 | 17 | Glover Quin | S | Not Injury Related | — |
| 2011 | 17 | Mike Brisiel | G | Ankle | Out |
| 2011 | 17 | Sherrick McManis | CB | Ankle | Out |
| 2011 | 17 | Troy Nolan | S | Ankle | Out |
| 2011 | 17 | Jason Allen | CB | Thumb | Probable |
| 2011 | 17 | Shaun Cody | DT | Knee | Probable |
| 2011 | 17 | Arian Foster | RB | Knee | Probable |
| 2011 | 17 | Earl Mitchell | DT | Knee | Probable |
| 2011 | 17 | Chris Myers | C | Knee | Probable |
| 2011 | 17 | Derek Newton | T | Knee | Probable |
| 2011 | 17 | Eric Winston | T | Calf | Probable |
| 2011 | 17 | T.J. Yates | QB | right Shoulder | Probable |
| 2011 | 17 | Owen Daniels | TE | Knee | Probable |
| 2011 | 17 | Joel Dreessen | TE | Knee | Probable |
| 2011 | 17 | Andre Johnson | WR | Hamstring | Probable |
| 2011 | 17 | Bryant Johnson | WR | Thigh | Probable |
| 2011 | 17 | Jeff Maehl | WR | Hamstring | Probable |
| 2011 | 18 (WC) | Jason Allen | CB | Back | Questionable |
| 2011 | 18 (WC) | Troy Nolan | S | Ankle | Questionable |
| 2011 | 18 (WC) | Bryan Braman | LB | Neck | Questionable |
| 2011 | 18 (WC) | Mike Brisiel | G | Ankle | Probable |
| 2011 | 18 (WC) | Antoine Caldwell | G | Ankle | Probable |
| 2011 | 18 (WC) | James Casey | RB | Knee | Probable |
| 2011 | 18 (WC) | Shaun Cody | DT | Knee | Probable |
| 2011 | 18 (WC) | Owen Daniels | TE | Knee | Probable |
| 2011 | 18 (WC) | Joel Dreessen | TE | Knee | Probable |
| 2011 | 18 (WC) | Arian Foster | RB | Knee | Probable |
| 2011 | 18 (WC) | Andre Johnson | WR | Hamstring | Probable |
| 2011 | 18 (WC) | Bryant Johnson | WR | Thigh | Probable |
| 2011 | 18 (WC) | Johnathan Joseph | CB | Achilles | Probable |
| 2011 | 18 (WC) | Sherrick McManis | CB | Ankle | Probable |
| 2011 | 18 (WC) | Chris Myers | C | Knee | Probable |
| 2011 | 18 (WC) | Derek Newton | T | Hip | Probable |
| 2011 | 18 (WC) | Glover Quin | S | Ankle / Elbow | Probable |
| 2011 | 18 (WC) | Eric Winston | T | Calf | Probable |
| 2011 | 18 (WC) | T.J. Yates | QB | left Shoulder | Probable |
| 2011 | 19 (DIV) | Mister Alexander | LB | Shoulder | Probable |
| 2011 | 19 (DIV) | Jason Allen | CB | Thumb | Probable |
| 2011 | 19 (DIV) | Bryan Braman | LB | Neck | Probable |
| 2011 | 19 (DIV) | Tim Bulman | DE | Calf | Probable |
| 2011 | 19 (DIV) | James Casey | RB | Knee / Foot | Probable |
| 2011 | 19 (DIV) | Shaun Cody | DT | Knee | Probable |
| 2011 | 19 (DIV) | Joel Dreessen | TE | Knee | Probable |
| 2011 | 19 (DIV) | Andre Johnson | WR | Knee | Probable |
| 2011 | 19 (DIV) | Johnathan Joseph | CB | Hip | Probable |
| 2011 | 19 (DIV) | Sherrick McManis | CB | Ankle | Probable |
| 2011 | 19 (DIV) | Chris Myers | C | Knee | Probable |
| 2011 | 19 (DIV) | Brooks Reed | LB | Knee | Probable |
| 2011 | 19 (DIV) | Ben Tate | RB | Shoulder | Probable |
| 2011 | 19 (DIV) | Eric Winston | T | Calf | Probable |
| 2011 | 19 (DIV) | T.J. Yates | QB | left Shoulder | Probable |
| 2011 | 19 (DIV) | Mike Brisiel | G | Ankle | Probable |
| 2011 | 19 (DIV) | Owen Daniels | TE | Hand / Knee | Probable |
| 2011 | 19 (DIV) | Troy Nolan | S | Ankle | Probable |
| 2012 | 1 | Bryan Braman | LB | Hamstring | Questionable |
| 2012 | 1 | Arian Foster | RB | Knee | Questionable |
| 2012 | 1 | Brooks Reed | LB | Hip | Questionable |
| 2012 | 1 | Shaun Cody | DT | Back / Ankle | Probable |
| 2012 | 1 | Brian Cushing | LB | Ribs | Probable |
| 2012 | 1 | Owen Daniels | TE | Illness | Probable |
| 2012 | 1 | Andre Johnson | WR | Chest | Probable |
| 2012 | 1 | Shiloh Keo | S | Neck | Probable |
| 2012 | 1 | Chris Myers | C | Knee | Probable |
| 2012 | 1 | Ben Tate | RB | Head | Probable |
| 2012 | 1 | J.J. Watt | DE | Elbow | Probable |
| 2012 | 2 | Bryan Braman | LB | Hamstring | Questionable |
| 2012 | 2 | Antoine Caldwell | G | Ankle | Probable |
| 2012 | 2 | Shaun Cody | DT | Back | Probable |
| 2012 | 2 | Brian Cushing | LB | Ribs | Probable |
| 2012 | 2 | Tim Dobbins | LB | Neck / Nose | Probable |
| 2012 | 2 | Arian Foster | RB | Illness / Back | Probable |
| 2012 | 2 | Johnathan Joseph | CB | Illness | Probable |
| 2012 | 2 | Brice McCain | CB | Foot | Probable |
| 2012 | 2 | Chris Myers | C | Ankle | Probable |
| 2012 | 2 | Brooks Reed | LB | Hip | Probable |
| 2012 | 2 | Wade Smith | G | Wrist | Probable |
| 2012 | 2 | J.J. Watt | DE | Elbow | Probable |
| 2012 | 2 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 3 | Tim Dobbins | LB | Hamstring | Questionable |
| 2012 | 3 | Connor Barwin | LB | Elbow | Probable |
| 2012 | 3 | Bryan Braman | LB | Hamstring | Probable |
| 2012 | 3 | Brandon Brooks | G | Thumb | Probable |
| 2012 | 3 | Antoine Caldwell | G | Ankle | Probable |
| 2012 | 3 | Brian Cushing | LB | Ribs | Probable |
| 2012 | 3 | Johnathan Joseph | CB | Groin | Probable |
| 2012 | 3 | Brice McCain | CB | Knee | Probable |
| 2012 | 3 | Chris Myers | C | Neck | Probable |
| 2012 | 3 | Jesse Nading | LB | Knee | Probable |
| 2012 | 3 | Brooks Reed | LB | Hip | Probable |
| 2012 | 3 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 4 | Lestar Jean | WR | Knee | Out |
| 2012 | 4 | Mister Alexander | LB | Ankle | Probable |
| 2012 | 4 | Alan Ball | CB | Foot | Probable |
| 2012 | 4 | Bryan Braman | LB | Hamstring | Probable |
| 2012 | 4 | Antoine Caldwell | G | Ankle | Probable |
| 2012 | 4 | Quintin Demps | S | Thumb | Probable |
| 2012 | 4 | Tim Dobbins | LB | Hamstring | Probable |
| 2012 | 4 | Arian Foster | RB | Knee | Probable |
| 2012 | 4 | Bradie James | LB | Chest | Probable |
| 2012 | 4 | Shiloh Keo | S | Thumb | Probable |
| 2012 | 4 | Brice McCain | CB | Knee | Probable |
| 2012 | 4 | Jesse Nading | LB | Knee | Probable |
| 2012 | 4 | Glover Quin | S | Hand | Probable |
| 2012 | 4 | Matt Schaub | QB | left Shoulder / right Elbow | Probable |
| 2012 | 4 | Connor Barwin | LB | Knee | Probable |
| 2012 | 4 | Andre Johnson | WR | Groin | Probable |
| 2012 | 4 | Johnathan Joseph | CB | Groin | Probable |
| 2012 | 4 | Brooks Reed | LB | Hip | Probable |
| 2012 | 4 | Antonio Smith | DE | Ankle / Illness | Probable |
| 2012 | 5 | Quintin Demps | S | Thumb / Forearm | Out |
| 2012 | 5 | Lestar Jean | WR | Knee | Out |
| 2012 | 5 | Ben Tate | RB | Toe | Questionable |
| 2012 | 5 | Mister Alexander | LB | Hip | Probable |
| 2012 | 5 | Bryan Braman | LB | Hamstring / Neck | Probable |
| 2012 | 5 | Antoine Caldwell | G | Ankle / Knee | Probable |
| 2012 | 5 | Shaun Cody | DT | Back | Probable |
| 2012 | 5 | Owen Daniels | TE | Thigh | Probable |
| 2012 | 5 | Tim Dobbins | LB | Hamstring | Probable |
| 2012 | 5 | Arian Foster | RB | Hamstring | Probable |
| 2012 | 5 | Bradie James | LB | Thigh | Probable |
| 2012 | 5 | Andre Johnson | WR | Groin | Probable |
| 2012 | 5 | Shiloh Keo | S | Neck | Probable |
| 2012 | 5 | Chris Myers | C | Back | Probable |
| 2012 | 5 | Jesse Nading | LB | Foot | Probable |
| 2012 | 5 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 5 | Wade Smith | G | Knee | Probable |
| 2012 | 6 | Quintin Demps | S | Thumb / Forearm | Out |
| 2012 | 6 | Mister Alexander | LB | Achilles | Probable |
| 2012 | 6 | Alan Ball | CB | Ankle | Probable |
| 2012 | 6 | Antoine Caldwell | G | Ankle / Foot | Probable |
| 2012 | 6 | Justin Forsett | RB | Thigh | Probable |
| 2012 | 6 | Arian Foster | RB | Knee | Probable |
| 2012 | 6 | Shayne Graham | K | right Calf | Probable |
| 2012 | 6 | Andre Johnson | WR | Groin | Probable |
| 2012 | 6 | Johnathan Joseph | CB | Knee | Probable |
| 2012 | 6 | Shiloh Keo | S | Neck | Probable |
| 2012 | 6 | Jesse Nading | LB | Foot | Probable |
| 2012 | 6 | Wade Smith | G | Foot | Probable |
| 2012 | 6 | Shaun Cody | DT | Back | Probable |
| 2012 | 6 | Lestar Jean | WR | Knee | Probable |
| 2012 | 6 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 6 | Ben Tate | RB | Toe | Probable |
| 2012 | 7 | Owen Daniels | TE | Not Injury Related | — |
| 2012 | 7 | Arian Foster | RB | Not Injury Related | — |
| 2012 | 7 | Andre Johnson | WR | Not Injury Related | — |
| 2012 | 7 | Antonio Smith | DE | Not Injury Related | — |
| 2012 | 7 | David Hunter | DT | Toe | Out |
| 2012 | 7 | Quintin Demps | S | Thumb / Forearm | Questionable |
| 2012 | 7 | Johnathan Joseph | CB | Groin | Questionable |
| 2012 | 7 | Bryan Braman | LB | Knee / Foot | Probable |
| 2012 | 7 | Antoine Caldwell | G | Concussion | Probable |
| 2012 | 7 | Shaun Cody | DT | Back | Probable |
| 2012 | 7 | Bradie James | LB | Calf | Probable |
| 2012 | 7 | Lestar Jean | WR | Knee | Probable |
| 2012 | 7 | Ben Jones | C | Knee / Illness | Probable |
| 2012 | 7 | Shiloh Keo | S | Neck / Back/Thumb | Probable |
| 2012 | 7 | Chris Myers | C | Hip | Probable |
| 2012 | 7 | Jesse Nading | LB | Foot / Neck | Probable |
| 2012 | 7 | Derek Newton | T | Forearm | Probable |
| 2012 | 7 | Wade Smith | G | Knee | Probable |
| 2012 | 7 | Ben Tate | RB | Toe | Probable |
| 2012 | 9 | Andre Johnson | WR | Not Injury Related | — |
| 2012 | 9 | Ben Tate | RB | Hamstring | Out |
| 2012 | 9 | Bryan Braman | LB | Neck | Probable |
| 2012 | 9 | Quintin Demps | S | Thumb / Forearm | Probable |
| 2012 | 9 | Lestar Jean | WR | Knee | Probable |
| 2012 | 9 | Ben Jones | C | Illness | Probable |
| 2012 | 9 | Shiloh Keo | S | Back | Probable |
| 2012 | 9 | Earl Mitchell | DT | Ankle | Probable |
| 2012 | 9 | Jesse Nading | LB | Foot / Neck | Probable |
| 2012 | 9 | Wade Smith | G | Knee | Probable |
| 2012 | 9 | Kevin Walter | WR | Illness | Probable |
| 2012 | 9 | Cody White | G | Illness | Probable |
| 2012 | 9 | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 9 | Shaun Cody | DT | Back | Probable |
| 2012 | 9 | Owen Daniels | TE | Hamstring | Probable |
| 2012 | 9 | Johnathan Joseph | CB | Groin | Probable |
| 2012 | 9 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 10 | Arian Foster | RB | Not Injury Related | — |
| 2012 | 10 | Shaun Cody | DT | Ribs | Out |
| 2012 | 10 | Ben Tate | RB | Hamstring | Out |
| 2012 | 10 | Owen Daniels | TE | Back | Questionable |
| 2012 | 10 | Bryan Braman | LB | Neck | Probable |
| 2012 | 10 | James Casey | RB | Illness | Probable |
| 2012 | 10 | Quintin Demps | S | Thumb / Forearm | Probable |
| 2012 | 10 | Lestar Jean | WR | Knee | Probable |
| 2012 | 10 | Johnathan Joseph | CB | Quadricep | Probable |
| 2012 | 10 | Shiloh Keo | S | Back | Probable |
| 2012 | 10 | Earl Mitchell | DT | Ankle | Probable |
| 2012 | 10 | Jesse Nading | LB | Foot / Neck | Probable |
| 2012 | 10 | Wade Smith | G | Knee | Probable |
| 2012 | 10 | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 10 | Brice McCain | CB | Knee | Probable |
| 2012 | 10 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 10 | Kevin Walter | WR | Groin | Probable |
| 2012 | 11 | Ben Tate | RB | Hamstring | Out |
| 2012 | 11 | Shaun Cody | DT | Ribs / Back | Questionable |
| 2012 | 11 | Owen Daniels | TE | Back | Questionable |
| 2012 | 11 | Tim Dobbins | LB | Shoulder | Questionable |
| 2012 | 11 | Alan Ball | CB | Ankle | Probable |
| 2012 | 11 | Quintin Demps | S | Thumb / Forearm/Toe | Probable |
| 2012 | 11 | Bradie James | LB | Thumb | Probable |
| 2012 | 11 | Lestar Jean | WR | Knee | Probable |
| 2012 | 11 | Brice McCain | CB | Knee | Probable |
| 2012 | 11 | Jesse Nading | LB | Foot | Probable |
| 2012 | 11 | Wade Smith | G | Knee | Probable |
| 2012 | 11 | Antonio Smith | DE | Illness / Ankle | Probable |
| 2012 | 11 | Kevin Walter | WR | Groin | Probable |
| 2012 | 11 | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 12 | DeVier Posey | WR | Knee / Hamstring | Doubtful |
| 2012 | 12 | Tim Dobbins | LB | Shoulder | Questionable |
| 2012 | 12 | Johnathan Joseph | CB | Hamstring | Questionable |
| 2012 | 12 | Ben Tate | RB | Hamstring | Questionable |
| 2012 | 12 | Shaun Cody | DT | Back / Ribs | Questionable |
| 2012 | 12 | Jared Crick | DE | Neck | Probable |
| 2012 | 12 | Owen Daniels | TE | Back | Probable |
| 2012 | 12 | Quintin Demps | S | Toe | Probable |
| 2012 | 12 | Bradie James | LB | Thumb | Probable |
| 2012 | 12 | Lestar Jean | WR | Knee | Probable |
| 2012 | 12 | Brice McCain | CB | Knee | Probable |
| 2012 | 12 | Chris Myers | C | Back | Probable |
| 2012 | 12 | Jesse Nading | LB | Foot | Probable |
| 2012 | 12 | Darryl Sharpton | LB | Neck / Knee/Hip | Probable |
| 2012 | 12 | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 12 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 12 | Wade Smith | G | Knee / Ribs | Probable |
| 2012 | 13 | Antoine Caldwell | G | Hamstring | Out |
| 2012 | 13 | Bradie James | LB | Hamstring | Out |
| 2012 | 13 | Johnathan Joseph | CB | Hamstring / Groin | Out |
| 2012 | 13 | Derek Newton | T | Knee | Out |
| 2012 | 13 | Brooks Reed | LB | Groin | Out |
| 2012 | 13 | Alan Ball | CB | Foot | Questionable |
| 2012 | 13 | Tyler Clutts | RB | Hip | Probable |
| 2012 | 13 | Shaun Cody | DT | Ribs / Back | Probable |
| 2012 | 13 | Jared Crick | DE | Neck | Probable |
| 2012 | 13 | Owen Daniels | TE | Back | Probable |
| 2012 | 13 | Justin Forsett | RB | Knee | Probable |
| 2012 | 13 | Arian Foster | RB | Finger | Probable |
| 2012 | 13 | Lestar Jean | WR | Knee | Probable |
| 2012 | 13 | Andre Johnson | WR | Groin | Probable |
| 2012 | 13 | Brice McCain | CB | Knee / Ribs | Probable |
| 2012 | 13 | Chris Myers | C | Elbow | Probable |
| 2012 | 13 | Jesse Nading | LB | Foot | Probable |
| 2012 | 13 | DeVier Posey | WR | Knee / Hamstring | Probable |
| 2012 | 13 | Glover Quin | S | Shoulder | Probable |
| 2012 | 13 | Darryl Sharpton | LB | Knee / Hip and Back | Probable |
| 2012 | 13 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 13 | Ben Tate | RB | Hamstring | Probable |
| 2012 | 13 | Kevin Walter | WR | Shoulder | Probable |
| 2012 | 13 | J.J. Watt | DE | Illness | Probable |
| 2012 | 13 | T.J. Yates | QB | right Shoulder | Probable |
| 2012 | 13 | Tim Dobbins | LB | Shoulder | Probable |
| 2012 | 13 | Wade Smith | G | Knee / Ribs | Probable |
| 2012 | 14 | Derek Newton | T | Knee | Out |
| 2012 | 14 | Brooks Reed | LB | Groin | Out |
| 2012 | 14 | Alan Ball | CB | Foot | Questionable |
| 2012 | 14 | Garrett Graham | TE | Concussion | Questionable |
| 2012 | 14 | Bryan Braman | LB | Neck | Probable |
| 2012 | 14 | Duane Brown | T | Back | Probable |
| 2012 | 14 | Antoine Caldwell | G | Hamstring | Probable |
| 2012 | 14 | Jared Crick | DE | Neck | Probable |
| 2012 | 14 | Owen Daniels | TE | Back | Probable |
| 2012 | 14 | Bradie James | LB | Hamstring | Probable |
| 2012 | 14 | Lestar Jean | WR | Knee | Probable |
| 2012 | 14 | Whitney Mercilus | LB | Hip | Probable |
| 2012 | 14 | Jesse Nading | LB | Foot | Probable |
| 2012 | 14 | DeVier Posey | WR | Knee / Hamstring | Probable |
| 2012 | 14 | Darryl Sharpton | LB | Toe | Probable |
| 2012 | 14 | Ben Tate | RB | Hamstring | Probable |
| 2012 | 14 | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 14 | Shaun Cody | DT | Ribs / Back | Probable |
| 2012 | 14 | Tim Dobbins | LB | Shoulder | Probable |
| 2012 | 14 | Johnathan Joseph | CB | Hamstring / Groin | Probable |
| 2012 | 14 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 14 | Wade Smith | G | Knee / Ribs | Probable |
| 2012 | 15 | Alan Ball | CB | Foot | Out |
| 2012 | 15 | Brooks Reed | LB | Groin | Out |
| 2012 | 15 | Derek Newton | T | Knee | Questionable |
| 2012 | 15 | Glover Quin | S | Hip | Questionable |
| 2012 | 15 | Darryl Sharpton | LB | Toe | Questionable |
| 2012 | 15 | Jared Crick | DE | Neck | Probable |
| 2012 | 15 | Owen Daniels | TE | Back | Probable |
| 2012 | 15 | Justin Forsett | RB | Knee | Probable |
| 2012 | 15 | Garrett Graham | TE | Concussion | Probable |
| 2012 | 15 | Bradie James | LB | Knee | Probable |
| 2012 | 15 | Lestar Jean | WR | Knee / Back | Probable |
| 2012 | 15 | Whitney Mercilus | LB | Knee | Probable |
| 2012 | 15 | Earl Mitchell | DT | Shoulder | Probable |
| 2012 | 15 | Jesse Nading | LB | Foot | Probable |
| 2012 | 15 | Ben Tate | RB | Hamstring / Foot | Probable |
| 2012 | 15 | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 15 | Shaun Cody | DT | Ribs / Back | Probable |
| 2012 | 15 | Tim Dobbins | LB | Shoulder | Probable |
| 2012 | 15 | Donnie Jones | P | right Knee | Probable |
| 2012 | 15 | Johnathan Joseph | CB | Groin | Probable |
| 2012 | 15 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 15 | Wade Smith | G | Knee / Ribs | Probable |
| 2012 | 16 | Alan Ball | CB | Foot | Out |
| 2012 | 16 | Bryan Braman | LB | Knee | Probable |
| 2012 | 16 | Tyler Clutts | RB | Abdominal | Probable |
| 2012 | 16 | Jared Crick | DE | Neck | Probable |
| 2012 | 16 | Owen Daniels | TE | Hamstring | Probable |
| 2012 | 16 | Justin Forsett | RB | Knee | Probable |
| 2012 | 16 | Barrett Ruud | LB | Knee | Probable |
| 2012 | 16 | Ben Tate | RB | Hamstring / Foot | Probable |
| 2012 | 16 | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 16 | Shaun Cody | DT | Back | Probable |
| 2012 | 16 | Tim Dobbins | LB | Shoulder / Thumb | Probable |
| 2012 | 16 | Johnathan Joseph | CB | Groin | Probable |
| 2012 | 16 | Derek Newton | T | Knee | Probable |
| 2012 | 16 | Glover Quin | S | Hip | Probable |
| 2012 | 16 | Brooks Reed | LB | Groin | Probable |
| 2012 | 16 | Darryl Sharpton | LB | Toe | Probable |
| 2012 | 16 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 16 | Wade Smith | G | Knee / Ribs | Probable |
| 2012 | 17 | Alan Ball | CB | Foot | Out |
| 2012 | 17 | Shiloh Keo | S | Ankle | Questionable |
| 2012 | 17 | Brooks Reed | LB | Groin | Questionable |
| 2012 | 17 | Connor Barwin | LB | Back / Elbow | Probable |
| 2012 | 17 | Tyler Clutts | RB | Abdominal | Probable |
| 2012 | 17 | Jared Crick | DE | Neck | Probable |
| 2012 | 17 | Justin Forsett | RB | Knee | Probable |
| 2012 | 17 | Arian Foster | RB | Arrhythmia | Probable |
| 2012 | 17 | Johnathan Joseph | CB | Groin / Quadricep | Probable |
| 2012 | 17 | Eddie Pleasant | S | Hamstring | Probable |
| 2012 | 17 | Glover Quin | S | Hip | Probable |
| 2012 | 17 | Darryl Sharpton | LB | Toe | Probable |
| 2012 | 17 | Ben Tate | RB | Hamstring | Probable |
| 2012 | 17 | J.J. Watt | DE | Chest | Probable |
| 2012 | 17 | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 17 | Shaun Cody | DT | Back | Probable |
| 2012 | 17 | Owen Daniels | TE | Hamstring / Neck | Probable |
| 2012 | 17 | Tim Dobbins | LB | Shoulder | Probable |
| 2012 | 17 | Derek Newton | T | Knee | Probable |
| 2012 | 17 | Antonio Smith | DE | Ankle | Probable |
| 2012 | 17 | Wade Smith | G | Knee / Ribs | Probable |
| 2012 | 18 (WC) | Tim Dobbins | LB | Ankle | — |
| 2012 | 18 (WC) | Antoine Caldwell | G | Back | Doubtful |
| 2012 | 18 (WC) | James Casey | RB | Knee | Probable |
| 2012 | 18 (WC) | Tyler Clutts | RB | Abdominal | Probable |
| 2012 | 18 (WC) | Justin Forsett | RB | Knee | Probable |
| 2012 | 18 (WC) | Shiloh Keo | S | Ankle | Probable |
| 2012 | 18 (WC) | DeVier Posey | WR | Foot | Probable |
| 2012 | 18 (WC) | Ben Tate | RB | Foot | Probable |
| 2012 | 18 (WC) | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 18 (WC) | Alan Ball | CB | Foot | Probable |
| 2012 | 18 (WC) | Shaun Cody | DT | Back | Probable |
| 2012 | 18 (WC) | Owen Daniels | TE | Chest / Knee | Probable |
| 2012 | 18 (WC) | Derek Newton | T | Knee | Probable |
| 2012 | 18 (WC) | Brooks Reed | LB | Groin | Probable |
| 2012 | 18 (WC) | Antonio Smith | DE | Ankle | Probable |
| 2012 | 18 (WC) | Wade Smith | G | Knee | Probable |
| 2012 | 19 (DIV) | Owen Daniels | TE | Shoulder | Probable |
| 2012 | 19 (DIV) | Justin Forsett | RB | Knee | Probable |
| 2012 | 19 (DIV) | Garrett Graham | TE | Concussion | Probable |
| 2012 | 19 (DIV) | Johnathan Joseph | CB | Illness | Probable |
| 2012 | 19 (DIV) | Shiloh Keo | S | Ankle | Probable |
| 2012 | 19 (DIV) | Glover Quin | S | Shoulder | Probable |
| 2012 | 19 (DIV) | Brooks Reed | LB | Groin | Probable |
| 2012 | 19 (DIV) | Ben Tate | RB | Foot | Probable |
| 2012 | 19 (DIV) | T.J. Yates | QB | right Elbow | Probable |
| 2012 | 19 (DIV) | Alan Ball | CB | Foot | Probable |
| 2012 | 19 (DIV) | Antoine Caldwell | G | Back | Probable |
| 2012 | 19 (DIV) | Shaun Cody | DT | Back | Probable |
| 2012 | 19 (DIV) | Derek Newton | T | Knee | Probable |
| 2012 | 19 (DIV) | Antonio Smith | DE | Ankle | Probable |
| 2012 | 19 (DIV) | Wade Smith | G | Knee | Probable |
| 2013 | 1 | David Quessenberry | T | Foot | Out |
| 2013 | 1 | Darryl Sharpton | LB | Concussion | Out |
| 2013 | 1 | Ed Reed | S | Hip | Questionable |
| 2013 | 1 | A.J. Bouye | CB | Knee | Probable |
| 2013 | 1 | Brian Cushing | LB | Knee | Probable |
| 2013 | 1 | Arian Foster | RB | Calf | Probable |
| 2013 | 1 | Garrett Graham | TE | Hip | Probable |
| 2013 | 1 | DeAndre Hopkins | WR | Concussion | Probable |
| 2013 | 1 | Brice McCain | CB | Knee | Probable |
| 2013 | 1 | Whitney Mercilus | LB | Hamstring | Probable |
| 2013 | 1 | Sam Montgomery | LB | Achilles | Probable |
| 2013 | 1 | Eddie Pleasant | S | Knee | Probable |
| 2013 | 1 | DeVier Posey | WR | Achilles | Probable |
| 2013 | 1 | Brooks Reed | LB | Back | Probable |
| 2013 | 1 | Wade Smith | G | Knee | Probable |
| 2013 | 2 | Ed Reed | S | Hip | Questionable |
| 2013 | 2 | Duane Brown | T | Ankle | Probable |
| 2013 | 2 | Brian Cushing | LB | Knee | Probable |
| 2013 | 2 | Owen Daniels | TE | Back / Groin | Probable |
| 2013 | 2 | Arian Foster | RB | Calf | Probable |
| 2013 | 2 | Garrett Graham | TE | Hip | Probable |
| 2013 | 2 | Tim Jamison | DE | Foot | Probable |
| 2013 | 2 | Shiloh Keo | S | Achilles | Probable |
| 2013 | 2 | Joe Mays | LB | Quadricep | Probable |
| 2013 | 2 | Brice McCain | CB | Knee | Probable |
| 2013 | 2 | Chris Myers | C | Back | Probable |
| 2013 | 2 | Derek Newton | T | Knee | Probable |
| 2013 | 2 | DeVier Posey | WR | Achilles | Probable |
| 2013 | 2 | Brooks Reed | LB | Back | Probable |
| 2013 | 2 | Darryl Sharpton | LB | Concussion | Probable |
| 2013 | 2 | Ben Tate | RB | Shoulder | Probable |
| 2013 | 2 | J.J. Watt | DE | Quadricep | Probable |
| 2013 | 2 | Wade Smith | G | Knee | Probable |
| 2013 | 3 | Duane Brown | T | Toe | Questionable |
| 2013 | 3 | Garrett Graham | TE | Hip / Groin | Questionable |
| 2013 | 3 | Ed Reed | S | Hip | Questionable |
| 2013 | 3 | Brian Cushing | LB | Knee | Probable |
| 2013 | 3 | Owen Daniels | TE | Not Injury Related | Probable |
| 2013 | 3 | Arian Foster | RB | Calf / Chest | Probable |
| 2013 | 3 | Andre Johnson | WR | Concussion / Lower Back | Probable |
| 2013 | 3 | Johnathan Joseph | CB | Not Injury Related | Probable |
| 2013 | 3 | Joe Mays | LB | Quadricep | Probable |
| 2013 | 3 | Brice McCain | CB | Knee | Probable |
| 2013 | 3 | Chris Myers | C | Back | Probable |
| 2013 | 3 | Derek Newton | T | Knee / Calf | Probable |
| 2013 | 3 | DeVier Posey | WR | Achilles / Foot | Probable |
| 2013 | 3 | Darryl Sharpton | LB | Hip | Probable |
| 2013 | 3 | Ben Tate | RB | Shoulder | Probable |
| 2013 | 3 | Wade Smith | G | Knee | Probable |
| 2013 | 4 | Tim Dobbins | LB | Hamstring | Out |
| 2013 | 4 | Duane Brown | T | Toe | Questionable |
| 2013 | 4 | Kareem Jackson | CB | Illness | Questionable |
| 2013 | 4 | Andre Johnson | WR | Shin | Questionable |
| 2013 | 4 | Johnathan Joseph | CB | Toe | Questionable |
| 2013 | 4 | Darryl Sharpton | LB | Hip / Foot | Questionable |
| 2013 | 4 | Brian Cushing | LB | Knee / Ankle | Probable |
| 2013 | 4 | Owen Daniels | TE | Knee | Probable |
| 2013 | 4 | Arian Foster | RB | Thumb | Probable |
| 2013 | 4 | Garrett Graham | TE | Hip / Groin | Probable |
| 2013 | 4 | Brice McCain | CB | Knee | Probable |
| 2013 | 4 | Chris Myers | C | Back | Probable |
| 2013 | 4 | Derek Newton | T | Knee / Calf | Probable |
| 2013 | 4 | Eddie Pleasant | S | Hamstring | Probable |
| 2013 | 4 | DeVier Posey | WR | Achilles | Probable |
| 2013 | 4 | Ed Reed | S | Hip | Probable |
| 2013 | 4 | Matt Schaub | QB | Ankle | Probable |
| 2013 | 4 | Ben Tate | RB | Shoulder | Probable |
| 2013 | 4 | Wade Smith | G | Knee | Probable |
| 2013 | 5 | Brandon Brooks | G | Toe | Out |
| 2013 | 5 | Tim Dobbins | LB | Hamstring | Out |
| 2013 | 5 | Duane Brown | T | Toe | Questionable |
| 2013 | 5 | Andre Johnson | WR | Shin | Questionable |
| 2013 | 5 | Bryan Braman | LB | Hamstring / Shoulder | Probable |
| 2013 | 5 | Brian Cushing | LB | Concussion | Probable |
| 2013 | 5 | Arian Foster | RB | Thumb / Back | Probable |
| 2013 | 5 | Garrett Graham | TE | Hip / Groin | Probable |
| 2013 | 5 | Johnathan Joseph | CB | Not Injury Related | Probable |
| 2013 | 5 | Brice McCain | CB | Knee | Probable |
| 2013 | 5 | Chris Myers | C | Biceps | Probable |
| 2013 | 5 | Derek Newton | T | Knee | Probable |
| 2013 | 5 | Eddie Pleasant | S | Hamstring | Probable |
| 2013 | 5 | DeVier Posey | WR | Achilles | Probable |
| 2013 | 5 | Ben Tate | RB | Shoulder | Probable |
| 2013 | 5 | J.J. Watt | DE | Groin / Nose | Probable |
| 2013 | 5 | Owen Daniels | TE | Knee | Probable |
| 2013 | 5 | Greg Jones | RB | Foot / Groin | Probable |
| 2013 | 5 | Ed Reed | S | Hip / Abdomen | Probable |
| 2013 | 5 | Darryl Sharpton | LB | Foot / Hip | Probable |
| 2013 | 5 | Wade Smith | G | Knee | Probable |
| 2013 | 6 | Tim Dobbins | LB | Hamstring | Out |
| 2013 | 6 | Andre Johnson | WR | Shin | Questionable |
| 2013 | 6 | Keshawn Martin | WR | Shoulder | Questionable |
| 2013 | 6 | Brian Cushing | LB | Knee | Probable |
| 2013 | 6 | Ryan Harris | T | Elbow | Probable |
| 2013 | 6 | Brice McCain | CB | Knee | Probable |
| 2013 | 6 | Chris Myers | C | Biceps | Probable |
| 2013 | 6 | Derek Newton | T | Knee | Probable |
| 2013 | 6 | Eddie Pleasant | S | Ankle | Probable |
| 2013 | 6 | DeVier Posey | WR | Achilles | Probable |
| 2013 | 6 | Antonio Smith | DE | Quadricep | Probable |
| 2013 | 6 | Ben Tate | RB | Elbow | Probable |
| 2013 | 6 | J.J. Watt | DE | Nose | Probable |
| 2013 | 6 | Bryan Braman | LB | Neck / Knee | Probable |
| 2013 | 6 | Brandon Brooks | G | Toe | Probable |
| 2013 | 6 | Duane Brown | T | Toe | Probable |
| 2013 | 6 | Arian Foster | RB | Thumb / Chest | Probable |
| 2013 | 6 | Ed Reed | S | Knee | Probable |
| 2013 | 6 | Darryl Sharpton | LB | Foot | Probable |
| 2013 | 6 | Wade Smith | G | Knee | Probable |
| 2013 | 7 | Tim Dobbins | LB | Hamstring | Out |
| 2013 | 7 | Matt Schaub | QB | Ankle / Foot | Out |
| 2013 | 7 | Brandon Brooks | G | Toe | Probable |
| 2013 | 7 | Duane Brown | T | Toe | Probable |
| 2013 | 7 | Brian Cushing | LB | Knee | Probable |
| 2013 | 7 | Arian Foster | RB | Thumb / Chest/Hamstring | Probable |
| 2013 | 7 | Andre Johnson | WR | Shin | Probable |
| 2013 | 7 | Brice McCain | CB | Knee | Probable |
| 2013 | 7 | Chris Myers | C | Biceps | Probable |
| 2013 | 7 | Derek Newton | T | Knee | Probable |
| 2013 | 7 | Eddie Pleasant | S | Toe | Probable |
| 2013 | 7 | DeVier Posey | WR | Achilles | Probable |
| 2013 | 7 | Ben Tate | RB | Elbow | Probable |
| 2013 | 7 | Greg Jones | RB | Ankle / Illness | Probable |
| 2013 | 7 | Keshawn Martin | WR | Shoulder | Probable |
| 2013 | 7 | Darryl Sharpton | LB | Foot | Probable |
| 2013 | 7 | Wade Smith | G | Knee | Probable |
| 2013 | 9 | Arian Foster | RB | Hamstring | Questionable |
| 2013 | 9 | Brandon Brooks | G | Toe | Probable |
| 2013 | 9 | Duane Brown | T | Toe | Probable |
| 2013 | 9 | Shiloh Keo | S | Achilles | Probable |
| 2013 | 9 | Keshawn Martin | WR | Shoulder | Probable |
| 2013 | 9 | Brice McCain | CB | Knee | Probable |
| 2013 | 9 | Earl Mitchell | DT | Knee | Probable |
| 2013 | 9 | Derek Newton | T | Knee / Elbow | Probable |
| 2013 | 9 | Eddie Pleasant | S | Toe | Probable |
| 2013 | 9 | DeVier Posey | WR | Calf | Probable |
| 2013 | 9 | Matt Schaub | QB | Ankle | Probable |
| 2013 | 9 | Darryl Sharpton | LB | Foot / Toe | Probable |
| 2013 | 9 | Wade Smith | G | Knee | Probable |
| 2013 | 9 | Ben Tate | RB | Ribs | Probable |
| 2013 | 10 | Tavares Gooden | LB | Not Injury Related | — |
| 2013 | 10 | Arian Foster | RB | Back | Out |
| 2013 | 10 | Mike Mohamed | LB | Hamstring | Out |
| 2013 | 10 | Brandon Brooks | G | Foot | Probable |
| 2013 | 10 | Andrew Gardner | T | Knee | Probable |
| 2013 | 10 | Garrett Graham | TE | Thigh | Probable |
| 2013 | 10 | Shiloh Keo | S | Ankle | Probable |
| 2013 | 10 | Keshawn Martin | WR | Shoulder | Probable |
| 2013 | 10 | Brice McCain | CB | Hip | Probable |
| 2013 | 10 | Earl Mitchell | DT | Knee | Probable |
| 2013 | 10 | Derek Newton | T | Knee / Elbow | Probable |
| 2013 | 10 | Darryl Sharpton | LB | Foot / Toe | Probable |
| 2013 | 10 | Wade Smith | G | Knee | Probable |
| 2013 | 10 | Ben Tate | RB | Ribs | Probable |
| 2013 | 11 | Ryan Griffin | TE | Concussion | Out |
| 2013 | 11 | Elbert Mack | CB | Hamstring / Groin | Out |
| 2013 | 11 | Kareem Jackson | CB | Chest | Questionable |
| 2013 | 11 | Shane Lechler | P | Illness | Questionable |
| 2013 | 11 | Joe Mays | LB | Knee / Abdomen | Questionable |
| 2013 | 11 | Mike Mohamed | LB | Hamstring | Questionable |
| 2013 | 11 | Brandon Brooks | G | Toe / Knee | Probable |
| 2013 | 11 | Andrew Gardner | T | Knee | Probable |
| 2013 | 11 | Ben Jones | C | Chest | Probable |
| 2013 | 11 | Shiloh Keo | S | Achilles / Hamstring | Probable |
| 2013 | 11 | Keshawn Martin | WR | Shoulder | Probable |
| 2013 | 11 | Brice McCain | CB | Hip | Probable |
| 2013 | 11 | Derek Newton | T | Knee / Elbow | Probable |
| 2013 | 11 | DeVier Posey | WR | Hip | Probable |
| 2013 | 11 | J.J. Watt | DE | Elbow | Probable |
| 2013 | 11 | Darryl Sharpton | LB | Foot / Toe | Probable |
| 2013 | 11 | Wade Smith | G | Knee | Probable |
| 2013 | 11 | Ben Tate | RB | Ribs | Probable |
| 2013 | 12 | Kareem Jackson | CB | Ribs | Out |
| 2013 | 12 | Elbert Mack | CB | Hamstring | Out |
| 2013 | 12 | Jawanza Starling | S | Hamstring | Out |
| 2013 | 12 | Mike Mohamed | LB | Hamstring | Questionable |
| 2013 | 12 | Darryl Sharpton | LB | Foot/Toe/Back | Questionable |
| 2013 | 12 | Jeff Tarpinian | LB | Groin | Questionable |
| 2013 | 12 | Duane Brown | T | Illness | Probable |
| 2013 | 12 | Ryan Griffin | TE | Concussion | Probable |
| 2013 | 12 | DeAndre Hopkins | WR | Illness | Probable |
| 2013 | 12 | Ben Jones | C | Ankle | Probable |
| 2013 | 12 | Shiloh Keo | S | Achilles / Hamstring | Probable |
| 2013 | 12 | Joe Mays | LB | Knee | Probable |
| 2013 | 12 | Chris Myers | C | Throat | Probable |
| 2013 | 12 | Derek Newton | T | Knee / Elbow | Probable |
| 2013 | 12 | J.J. Watt | DE | Back | Probable |
| 2013 | 12 | Cody White | G | Neck | Probable |
| 2013 | 12 | Wade Smith | G | Knee | Probable |
| 2013 | 12 | Ben Tate | RB | Ribs/Ankle/Toe | Probable |
| 2013 | 13 | Jawanza Starling | S | Hamstring | Out |
| 2013 | 13 | Kareem Jackson | CB | Ribs | Questionable |
| 2013 | 13 | Brice McCain | CB | Hamstring | Questionable |
| 2013 | 13 | Shiloh Keo | S | Neck | Probable |
| 2013 | 13 | Elbert Mack | CB | Hamstring | Probable |
| 2013 | 13 | Joe Mays | LB | Knee | Probable |
| 2013 | 13 | Derek Newton | T | Knee | Probable |
| 2013 | 13 | Matt Schaub | QB | Not Injury Related | Probable |
| 2013 | 13 | Antonio Smith | DE | Not Injury Related | Probable |
| 2013 | 13 | Mike Mohamed | LB | Hamstring | Probable |
| 2013 | 13 | Darryl Sharpton | LB | Back | Probable |
| 2013 | 13 | Wade Smith | G | Knee | Probable |
| 2013 | 13 | Jeff Tarpinian | LB | Groin | Probable |
| 2013 | 13 | Ben Tate | RB | Ribs | Probable |
| 2013 | 14 | Greg Jones | RB | Knee | Questionable |
| 2013 | 14 | Shiloh Keo | S | Neck | Probable |
| 2013 | 14 | Brice McCain | CB | Hamstring | Probable |
| 2013 | 14 | Derek Newton | T | Knee | Probable |
| 2013 | 14 | Antonio Smith | DE | Not Injury Related | Probable |
| 2013 | 14 | Jawanza Starling | S | Hamstring | Probable |
| 2013 | 14 | D.J. Swearinger | S | Foot | Probable |
| 2013 | 14 | Kareem Jackson | CB | Ribs | Probable |
| 2013 | 14 | Johnathan Joseph | CB | Groin | Probable |
| 2013 | 14 | Joe Mays | LB | Knee | Probable |
| 2013 | 14 | Whitney Mercilus | LB | Hip | Probable |
| 2013 | 14 | Mike Mohamed | LB | Hamstring | Probable |
| 2013 | 14 | Chris Myers | C | Elbow | Probable |
| 2013 | 14 | Darryl Sharpton | LB | Knee | Probable |
| 2013 | 14 | Wade Smith | G | Knee | Probable |
| 2013 | 14 | Jeff Tarpinian | LB | Groin | Probable |
| 2013 | 14 | Ben Tate | RB | Ribs / Ankle | Probable |
| 2013 | 15 | Jake Byrne | TE | Illness | — |
| 2013 | 15 | Garrett Graham | TE | Hamstring | Questionable |
| 2013 | 15 | DeAndre Hopkins | WR | Ankle | Questionable |
| 2013 | 15 | Kareem Jackson | CB | Ribs | Probable |
| 2013 | 15 | Johnathan Joseph | CB | Groin | Probable |
| 2013 | 15 | Case Keenum | QB | left Shoulder | Probable |
| 2013 | 15 | Shiloh Keo | S | Illness | Probable |
| 2013 | 15 | Joe Mays | LB | Knee | Probable |
| 2013 | 15 | Brice McCain | CB | Groin | Probable |
| 2013 | 15 | Derek Newton | T | Knee | Probable |
| 2013 | 15 | D.J. Swearinger | S | Foot | Probable |
| 2013 | 15 | Jeff Tarpinian | LB | Groin | Probable |
| 2013 | 15 | Josh Victorian | CB | Back | Probable |
| 2013 | 15 | T.J. Yates | QB | Back | Probable |
| 2013 | 15 | Greg Jones | RB | Knee | Probable |
| 2013 | 15 | Darryl Sharpton | LB | Wrist | Probable |
| 2013 | 15 | Wade Smith | G | Knee | Probable |
| 2013 | 15 | Ben Tate | RB | Ribs | Probable |
| 2013 | 16 | Case Keenum | QB | right Thumb | Out |
| 2013 | 16 | DeVier Posey | WR | Ankle | Out |
| 2013 | 16 | Garrett Graham | TE | Hamstring | Questionable |
| 2013 | 16 | Brad Smelley | RB | Back | Questionable |
| 2013 | 16 | DeAndre Hopkins | WR | Ankle | Probable |
| 2013 | 16 | Derek Newton | T | Knee | Probable |
| 2013 | 16 | D.J. Swearinger | S | Foot | Probable |
| 2013 | 16 | Josh Victorian | CB | Back | Probable |
| 2013 | 16 | J.J. Watt | DE | Hand | Probable |
| 2013 | 16 | Jonathan Weeks | LS | Back | Probable |
| 2013 | 16 | T.J. Yates | QB | Back | Probable |
| 2013 | 16 | Andre Johnson | WR | Wrist | Probable |
| 2013 | 16 | Greg Jones | RB | Knee | Probable |
| 2013 | 16 | Johnathan Joseph | CB | Groin | Probable |
| 2013 | 16 | Joe Mays | LB | Knee | Probable |
| 2013 | 16 | Darryl Sharpton | LB | Ankle | Probable |
| 2013 | 16 | Antonio Smith | DE | Knee | Probable |
| 2013 | 16 | Wade Smith | G | Knee | Probable |
| 2013 | 16 | Justin Tuggle | LB | Elbow | Probable |
| 2013 | 17 | DeVier Posey | WR | Ankle | Out |
| 2013 | 17 | Dennis Johnson | RB | Hip | Questionable |
| 2013 | 17 | Case Keenum | QB | right Thumb | Questionable |
| 2013 | 17 | Joe Mays | LB | Knee | Questionable |
| 2013 | 17 | Garrett Graham | TE | Hamstring | Probable |
| 2013 | 17 | Brad Smelley | RB | Calf / Back | Probable |
| 2013 | 17 | DeAndre Hopkins | WR | Ankle | Probable |
| 2013 | 17 | Andre Johnson | WR | Wrist | Probable |
| 2013 | 17 | Derek Newton | T | Knee | Probable |
| 2013 | 17 | Brooks Reed | LB | Thumb | Probable |
| 2013 | 17 | D.J. Swearinger | S | Foot | Probable |
| 2013 | 17 | Justin Tuggle | LB | Elbow | Probable |
| 2013 | 17 | Josh Victorian | S | Back | Probable |
| 2013 | 17 | T.J. Yates | QB | Back | Probable |
| 2013 | 17 | Ryan Griffin | TE | Knee | Probable |
| 2013 | 17 | Greg Jones | RB | Knee | Probable |
| 2013 | 17 | Darryl Sharpton | LB | Knee | Probable |
| 2013 | 17 | Antonio Smith | DE | Knee | Probable |
| 2013 | 17 | Wade Smith | G | Knee | Probable |
| 2014 | 1 | Garrett Graham | TE | Back | Questionable |
| 2014 | 1 | Shiloh Keo | S | Calf | Questionable |
| 2014 | 1 | A.J. Bouye | CB | Shoulder | Probable |
| 2014 | 1 | Tyson Clabo | T | Ankle | Probable |
| 2014 | 1 | Brian Cushing | LB | Ankle | Probable |
| 2014 | 1 | Tim Jamison | DE | Groin | Probable |
| 2014 | 1 | Johnathan Joseph | CB | Foot | Probable |
| 2014 | 1 | Mike Mohamed | LB | Quadricep | Probable |
| 2014 | 1 | Chris Myers | C | Toe | Probable |
| 2014 | 1 | Louis Nix | DT | Knee | Probable |
| 2014 | 1 | Jay Prosch | RB | Hand | Probable |
| 2014 | 1 | Xavier Su'a-Filo | G | Back | Probable |
| 2014 | 1 | Justin Tuggle | LB | Knee | Probable |
| 2014 | 2 | Jadeveon Clowney | LB | Knee | Out |
| 2014 | 2 | C.J. Fiedorowicz | TE | Foot | Out |
| 2014 | 2 | Shiloh Keo | S | Calf | Out |
| 2014 | 2 | Derek Newton | T | Elbow / Illness | Probable |
| 2014 | 2 | J.J. Watt | DE | Ankle / Illness | Probable |
| 2014 | 2 | A.J. Bouye | CB | Shoulder | Probable |
| 2014 | 2 | Tyson Clabo | T | Ankle | Probable |
| 2014 | 2 | Brian Cushing | LB | Ankle | Probable |
| 2014 | 2 | Arian Foster | RB | Ribs | Probable |
| 2014 | 2 | Garrett Graham | TE | Back | Probable |
| 2014 | 2 | Tim Jamison | DE | Groin | Probable |
| 2014 | 2 | Andre Johnson | WR | Ankle | Probable |
| 2014 | 2 | Johnathan Joseph | CB | Foot | Probable |
| 2014 | 2 | Elbert Mack | CB | Foot | Probable |
| 2014 | 2 | Mike Mohamed | LB | Quadricep | Probable |
| 2014 | 2 | Chris Myers | C | Foot | Probable |
| 2014 | 2 | Louis Nix | DT | Wrist | Probable |
| 2014 | 2 | Jay Prosch | RB | Hand | Probable |
| 2014 | 2 | Xavier Su'a-Filo | G | Back | Probable |
| 2014 | 3 | Jadeveon Clowney | LB | Knee | Out |
| 2014 | 3 | Shiloh Keo | S | Calf | Out |
| 2014 | 3 | Ben Jones | G | Ankle / Knee | Questionable |
| 2014 | 3 | Arian Foster | RB | Hamstring | Questionable |
| 2014 | 3 | D.J. Swearinger | S | Elbow | Questionable |
| 2014 | 3 | Akeem Dent | LB | Hamstring | Probable |
| 2014 | 3 | C.J. Fiedorowicz | TE | Foot | Probable |
| 2014 | 3 | Garrett Graham | TE | Ankle | Probable |
| 2014 | 3 | DeAndre Hopkins | WR | Illness | Probable |
| 2014 | 3 | Tim Jamison | DE | Groin | Probable |
| 2014 | 3 | Andre Johnson | WR | Ankle | Probable |
| 2014 | 3 | Johnathan Joseph | CB | Foot | Probable |
| 2014 | 3 | Louis Nix | DT | Wrist | Probable |
| 2014 | 3 | Jay Prosch | RB | Hand | Probable |
| 2014 | 4 | Jadeveon Clowney | LB | Knee | Out |
| 2014 | 4 | Shiloh Keo | S | Calf | Out |
| 2014 | 4 | Eddie Pleasant | S | Ankle | Out |
| 2014 | 4 | A.J. Bouye | CB | Groin | Questionable |
| 2014 | 4 | Shane Lechler | P | left Hip | Questionable |
| 2014 | 4 | Arian Foster | RB | Hamstring | Questionable |
| 2014 | 4 | Jared Crick | DE | Neck | Probable |
| 2014 | 4 | Kareem Jackson | CB | Thigh | Probable |
| 2014 | 4 | Tim Jamison | DE | Groin | Probable |
| 2014 | 4 | Andre Johnson | WR | Ankle | Probable |
| 2014 | 4 | Ben Jones | G | Knee | Probable |
| 2014 | 4 | Johnathan Joseph | CB | Foot / Neck/Knee | Probable |
| 2014 | 4 | D.J. Swearinger | S | Elbow / Hip | Probable |
| 2014 | 5 | A.J. Bouye | CB | Groin | Out |
| 2014 | 5 | Jadeveon Clowney | LB | Knee | Out |
| 2014 | 5 | Darryl Morris | CB | Ankle | Out |
| 2014 | 5 | Eddie Pleasant | S | Ankle | Out |
| 2014 | 5 | Andre Johnson | WR | Ankle | Questionable |
| 2014 | 5 | Tim Jamison | DE | Groin | Questionable |
| 2014 | 5 | Shane Lechler | P | left Hip | Probable |
| 2014 | 5 | Duane Brown | T | Knee | Probable |
| 2014 | 5 | Brian Cushing | LB | Knee | Probable |
| 2014 | 5 | Akeem Dent | LB | Shoulder | Probable |
| 2014 | 5 | Damaris Johnson | WR | Foot | Probable |
| 2014 | 5 | Ben Jones | G | Knee | Probable |
| 2014 | 5 | Johnathan Joseph | CB | Knee | Probable |
| 2014 | 5 | Chris Myers | C | Ankle | Probable |
| 2014 | 5 | D.J. Swearinger | S | Elbow | Probable |
| 2014 | 5 | Arian Foster | RB | Hamstring | Probable |
| 2014 | 5 | J.J. Watt | DE | Thigh | Probable |
| 2014 | 6 | Ricky Sapp | LB | Hamstring | — |
| 2014 | 6 | Jadeveon Clowney | LB | Knee | Out |
| 2014 | 6 | Darryl Morris | CB | Ankle | Out |
| 2014 | 6 | Andre Johnson | WR | Ankle | Questionable |
| 2014 | 6 | Brian Cushing | LB | Knee | Probable |
| 2014 | 6 | Alfred Blue | RB | Knee | Probable |
| 2014 | 6 | A.J. Bouye | CB | Groin | Probable |
| 2014 | 6 | Brandon Brooks | G | Ankle | Probable |
| 2014 | 6 | Akeem Dent | LB | Shoulder | Probable |
| 2014 | 6 | Ryan Fitzpatrick | QB | Calf | Probable |
| 2014 | 6 | Arian Foster | RB | Hamstring | Probable |
| 2014 | 6 | Tim Jamison | DE | Groin | Probable |
| 2014 | 6 | Damaris Johnson | WR | Foot | Probable |
| 2014 | 6 | Ben Jones | G | Knee | Probable |
| 2014 | 6 | Shane Lechler | P | left Hip | Probable |
| 2014 | 6 | Derek Newton | T | Ankle | Probable |
| 2014 | 6 | Ryan Pickett | DT | Knee | Probable |
| 2014 | 6 | Eddie Pleasant | S | Ankle | Probable |
| 2014 | 6 | D.J. Swearinger | S | Elbow | Probable |
| 2014 | 6 | Jeff Tarpinian | LB | Thigh | Probable |
| 2014 | 6 | J.J. Watt | DE | Thigh | Probable |
| 2014 | 6 | Johnathan Joseph | CB | Knee | Probable |
| 2014 | 7 | Darryl Morris | CB | Ankle | Out |
| 2014 | 7 | Jadeveon Clowney | LB | Knee | Questionable |
| 2014 | 7 | Mike Mohamed | LB | Calf | Questionable |
| 2014 | 7 | Brandon Brooks | G | Illness | Probable |
| 2014 | 7 | Brian Cushing | LB | Knee | Probable |
| 2014 | 7 | Arian Foster | RB | Groin | Probable |
| 2014 | 7 | DeAndre Hopkins | WR | Hand | Probable |
| 2014 | 7 | Tim Jamison | DE | Groin | Probable |
| 2014 | 7 | Andre Johnson | WR | Ankle | Probable |
| 2014 | 7 | Johnathan Joseph | CB | Knee | Probable |
| 2014 | 7 | Chris Myers | C | Not Injury Related | Probable |
| 2014 | 7 | Derek Newton | T | Elbow | Probable |
| 2014 | 7 | Brooks Reed | LB | Groin | Probable |
| 2014 | 7 | Jeff Tarpinian | LB | Knee | Probable |
| 2014 | 7 | J.J. Watt | DE | Thigh | Probable |
| 2014 | 8 | Arian Foster | RB | Not Injury Related | — |
| 2014 | 8 | Darryl Morris | CB | Ankle | Out |
| 2014 | 8 | Jeff Tarpinian | LB | Knee | Out |
| 2014 | 8 | Brian Cushing | LB | Knee | Questionable |
| 2014 | 8 | Jadeveon Clowney | LB | Knee | Questionable |
| 2014 | 8 | Brooks Reed | LB | Groin | Questionable |
| 2014 | 8 | John Simon | LB | Ankle | Questionable |
| 2014 | 8 | Akeem Dent | LB | Wrist | Probable |
| 2014 | 8 | Tim Jamison | DE | Groin | Probable |
| 2014 | 8 | Andre Johnson | WR | Ankle | Probable |
| 2014 | 8 | Mike Mohamed | LB | Calf | Probable |
| 2014 | 8 | Jerrell Powe | DT | Shoulder | Probable |
| 2014 | 8 | Johnathan Joseph | CB | Knee | Probable |
| 2014 | 9 | Jeff Tarpinian | LB | Knee | Out |
| 2014 | 9 | Jadeveon Clowney | LB | Knee / Illness | Questionable |
| 2014 | 9 | Darryl Morris | CB | Ankle | Questionable |
| 2014 | 9 | Brian Cushing | LB | Knee | Questionable |
| 2014 | 9 | Tim Jamison | DE | Groin | Probable |
| 2014 | 9 | Whitney Mercilus | LB | Shoulder | Probable |
| 2014 | 9 | Jumal Rolle | CB | Wrist | Probable |
| 2014 | 9 | Alfred Blue | RB | Ankle | Probable |
| 2014 | 9 | Arian Foster | RB | Knee | Probable |
| 2014 | 9 | Andre Johnson | WR | Ankle | Probable |
| 2014 | 9 | Johnathan Joseph | CB | Knee | Probable |
| 2014 | 9 | Brooks Reed | LB | Groin | Probable |
| 2014 | 9 | John Simon | LB | Ankle | Probable |
| 2014 | 11 | Kareem Jackson | CB | Knee | Out |
| 2014 | 11 | Arian Foster | RB | Groin | Questionable |
| 2014 | 11 | Johnathan Joseph | CB | Concussion / Knee | Probable |
| 2014 | 11 | Darryl Morris | CB | Ankle | Probable |
| 2014 | 11 | Brooks Reed | LB | Groin | Probable |
| 2014 | 11 | John Simon | LB | Ankle | Probable |
| 2014 | 11 | Jeff Tarpinian | LB | Knee | Probable |
| 2014 | 11 | Justin Tuggle | LB | Shoulder | Probable |
| 2014 | 11 | Jadeveon Clowney | LB | Knee | Probable |
| 2014 | 11 | Brian Cushing | LB | Knee | Probable |
| 2014 | 12 | Kareem Jackson | CB | Knee | Out |
| 2014 | 12 | Arian Foster | RB | Groin | Questionable |
| 2014 | 12 | Max Bullough | LB | Hamstring | Questionable |
| 2014 | 12 | Andre Johnson | WR | Not Injury Related | Probable |
| 2014 | 12 | Tyson Clabo | T | Foot | Probable |
| 2014 | 12 | Jonathan Grimes | RB | Ankle | Probable |
| 2014 | 12 | Ryan Mallett | QB | Chest | Probable |
| 2014 | 12 | Whitney Mercilus | LB | Knee | Probable |
| 2014 | 12 | Mike Mohamed | LB | Hip | Probable |
| 2014 | 12 | Darryl Morris | CB | Ankle | Probable |
| 2014 | 12 | Jeff Tarpinian | LB | Knee | Probable |
| 2014 | 12 | Justin Tuggle | LB | Shoulder | Probable |
| 2014 | 12 | Jadeveon Clowney | LB | Knee | Probable |
| 2014 | 12 | Brian Cushing | LB | Knee | Probable |
| 2014 | 12 | Akeem Dent | LB | Neck | Probable |
| 2014 | 12 | Johnathan Joseph | CB | Knee | Probable |
| 2014 | 13 | Jadeveon Clowney | LB | Knee | Out |
| 2014 | 13 | Kareem Jackson | CB | Knee | Out |
| 2014 | 13 | Akeem Dent | LB | Neck | Questionable |
| 2014 | 13 | Max Bullough | LB | Hamstring | Probable |
| 2014 | 13 | Tyson Clabo | T | Foot | Probable |
| 2014 | 13 | Andre Johnson | WR | Not Injury Related | Probable |
| 2014 | 13 | Kendrick Lewis | S | Knee | Probable |
| 2014 | 13 | Mike Mohamed | LB | Hip | Probable |
| 2014 | 13 | Darryl Morris | CB | Thigh | Probable |
| 2014 | 13 | Jeff Tarpinian | LB | Knee | Probable |
| 2014 | 13 | Brian Cushing | LB | Knee | Probable |
| 2014 | 13 | Arian Foster | RB | Groin | Probable |
| 2014 | 13 | Johnathan Joseph | CB | Knee | Probable |
| 2014 | 13 | Ryan Pickett | DT | Back | Probable |
| 2014 | 13 | D.J. Swearinger | S | Ankle | Probable |
| 2014 | 14 | Jadeveon Clowney | LB | Knee | Out |
| 2014 | 14 | Garrett Graham | TE | Ankle | Out |
| 2014 | 14 | Danieal Manning | S | Hamstring | Questionable |
| 2014 | 14 | Tyson Clabo | T | Foot | Probable |
| 2014 | 14 | Anthony Denham | TE | Illness | Probable |
| 2014 | 14 | Arian Foster | RB | Groin | Probable |
| 2014 | 14 | Jonathan Grimes | RB | Ankle | Probable |
| 2014 | 14 | Andre Johnson | WR | Not Injury Related | Probable |
| 2014 | 14 | Shane Lechler | P | Biceps | Probable |
| 2014 | 14 | Derek Newton | T | Knee | Probable |
| 2014 | 14 | Ryan Pickett | DT | Back | Probable |
| 2014 | 14 | Jeff Tarpinian | LB | Knee | Probable |
| 2014 | 14 | Brian Cushing | LB | Knee | Probable |
| 2014 | 14 | Akeem Dent | LB | Neck | Probable |
| 2014 | 14 | Kareem Jackson | CB | Knee | Probable |
| 2014 | 14 | Johnathan Joseph | CB | Ankle | Probable |
| 2014 | 15 | Tim Jamison | DE | Knee | — |
| 2014 | 15 | Garrett Graham | TE | Ankle | Out |
| 2014 | 15 | Whitney Mercilus | LB | Back | Out |
| 2014 | 15 | Xavier Su'a-Filo | G | Back | Out |
| 2014 | 15 | Andre Johnson | WR | Concussion | Questionable |
| 2014 | 15 | Tyson Clabo | T | Foot | Probable |
| 2014 | 15 | Brian Cushing | LB | Back / Ankle | Probable |
| 2014 | 15 | Akeem Dent | LB | Neck | Probable |
| 2014 | 15 | Arian Foster | RB | Groin | Probable |
| 2014 | 15 | Kareem Jackson | CB | Knee | Probable |
| 2014 | 15 | Johnathan Joseph | CB | Knee / Achilles | Probable |
| 2014 | 15 | Danieal Manning | S | Hamstring | Probable |
| 2014 | 15 | Jeff Tarpinian | LB | Knee | Probable |
| 2014 | 16 | J.J. Watt | DE | Not Injury Related | — |
| 2014 | 16 | Garrett Graham | TE | Ankle | Out |
| 2014 | 16 | Mike Mohamed | LB | Concussion | Out |
| 2014 | 16 | Tom Savage | QB | Knee | Out |
| 2014 | 16 | Xavier Su'a-Filo | G | Back | Out |
| 2014 | 16 | DeAndre Hopkins | WR | Ankle | Questionable |
| 2014 | 16 | Andre Johnson | WR | Concussion / Not Injury Related | Probable |
| 2014 | 16 | Tyson Clabo | T | Foot / Back | Probable |
| 2014 | 16 | Brian Cushing | LB | Ankle | Probable |
| 2014 | 16 | Akeem Dent | LB | Neck | Probable |
| 2014 | 16 | Arian Foster | RB | Hip | Probable |
| 2014 | 16 | Kareem Jackson | CB | Knee | Probable |
| 2014 | 16 | Johnathan Joseph | CB | Ankle | Probable |
| 2014 | 16 | Whitney Mercilus | LB | Back | Probable |
| 2014 | 16 | DeVier Posey | WR | Calf | Probable |
| 2014 | 16 | Jeff Tarpinian | LB | Knee | Probable |
| 2014 | 17 | Garrett Graham | TE | Ankle | Out |
| 2014 | 17 | Mike Mohamed | LB | Concussion | Out |
| 2014 | 17 | DeVier Posey | WR | Calf | Out |
| 2014 | 17 | Tom Savage | QB | Knee | Out |
| 2014 | 17 | Brian Cushing | LB | Ankle | Probable |
| 2014 | 17 | Arian Foster | RB | Not Injury Related | Probable |
| 2014 | 17 | Andre Johnson | WR | Not Injury Related | Probable |
| 2014 | 17 | Johnathan Joseph | CB | Ankle | Probable |
| 2014 | 17 | Whitney Mercilus | LB | Back / Finger | Probable |
| 2014 | 17 | Jeff Tarpinian | LB | Knee | Probable |
| 2014 | 17 | Brandon Brooks | G | Knee / Ankle | Probable |
| 2014 | 17 | Tyson Clabo | T | Shoulder | Probable |
| 2014 | 17 | C.J. Fiedorowicz | TE | Shoulder | Probable |
| 2014 | 17 | DeAndre Hopkins | WR | Wrist | Probable |
| 2014 | 17 | Kareem Jackson | CB | Back | Probable |
| 2014 | 17 | Ryan Pickett | DT | Groin | Probable |
| 2014 | 17 | Xavier Su'a-Filo | G | Back | Probable |
| 2015 | 1 | Lonnie Ballentine | S | Knee | Out |
| 2015 | 1 | Arian Foster | RB | Groin | Out |
| 2015 | 1 | Mike Mohamed | LB | Calf | Out |
| 2015 | 1 | Xavier Su'a-Filo | G | Calf | Out |
| 2015 | 1 | Carlos Thompson | LB | Concussion | Out |
| 2015 | 1 | Duane Brown | T | Hand | Probable |
| 2015 | 1 | Jadeveon Clowney | LB | Knee | Probable |
| 2015 | 1 | Christian Covington | DT | Shoulder | Probable |
| 2015 | 1 | Benardrick McKinney | LB | Knee | Probable |
| 2015 | 2 | Lonnie Ballentine | S | Knee | Out |
| 2015 | 2 | Mike Mohamed | LB | Calf | Out |
| 2015 | 2 | Xavier Su'a-Filo | G | Calf | Out |
| 2015 | 2 | Arian Foster | RB | Groin | Out |
| 2015 | 2 | Duane Brown | T | Hand | Questionable |
| 2015 | 2 | Jeff Adams | T | Abdomen | Probable |
| 2015 | 2 | Christian Covington | DT | Shoulder | Probable |
| 2015 | 2 | Kevin Johnson | CB | Thigh | Probable |
| 2015 | 2 | Carlos Thompson | LB | Concussion | Probable |
| 2015 | 2 | Nate Washington | WR | Abdomen | Probable |
| 2015 | 3 | Jeff Adams | T | Knee | Out |
| 2015 | 3 | Lonnie Ballentine | S | Knee | Out |
| 2015 | 3 | Duane Brown | T | Hand | Out |
| 2015 | 3 | Mike Mohamed | LB | Calf | Out |
| 2015 | 3 | Arian Foster | RB | Groin | Out |
| 2015 | 3 | C.J. Fiedorowicz | TE | Knee | Questionable |
| 2015 | 3 | Jonathan Grimes | RB | Knee | Questionable |
| 2015 | 3 | Xavier Su'a-Filo | G | Calf | Questionable |
| 2015 | 3 | Chris Clark | T | Knee / Elbow | Probable |
| 2015 | 3 | DeAndre Hopkins | WR | Concussion | Probable |
| 2015 | 3 | Derek Newton | T | Elbow | Probable |
| 2015 | 4 | Lonnie Ballentine | S | Knee | Out |
| 2015 | 4 | Akeem Dent | LB | Hamstring | Out |
| 2015 | 4 | Jonathan Grimes | RB | Knee | Out |
| 2015 | 4 | Duane Brown | T | Hand | Questionable |
| 2015 | 4 | Arian Foster | RB | Groin | Questionable |
| 2015 | 4 | Brandon Brooks | G | Ankle | Probable |
| 2015 | 4 | Eddie Pleasant | S | Thigh | Probable |
| 2015 | 4 | Xavier Su'a-Filo | G | Calf | Probable |
| 2015 | 4 | Jadeveon Clowney | LB | Shoulder | Probable |
| 2015 | 4 | Johnathan Joseph | CB | Hip | Probable |
| 2015 | 4 | Ryan Mallett | QB | Chest | Probable |
| 2015 | 4 | Derek Newton | T | Ankle | Probable |
| 2015 | 5 | Quintin Demps | S | Hamstring | Out |
| 2015 | 5 | Akeem Dent | LB | Hamstring | Out |
| 2015 | 5 | Jonathan Grimes | RB | Hamstring | Out |
| 2015 | 5 | Cecil Shorts | WR | Shoulder | Out |
| 2015 | 5 | Nate Washington | WR | Hamstring | Out |
| 2015 | 5 | Whitney Mercilus | LB | Thigh | Questionable |
| 2015 | 5 | Lonnie Ballentine | S | Knee | Questionable |
| 2015 | 5 | Chris Polk | RB | Knee | Questionable |
| 2015 | 5 | Max Bullough | LB | Shoulder | Probable |
| 2015 | 5 | Brian Cushing | LB | Foot | Probable |
| 2015 | 5 | Ryan Mallett | QB | Chest | Probable |
| 2015 | 5 | Derek Newton | T | Ankle | Probable |
| 2015 | 5 | Xavier Su'a-Filo | G | Calf | Probable |
| 2015 | 5 | Vince Wilfork | DT | Ankle | Probable |
| 2015 | 5 | Duane Brown | T | Hand | Probable |
| 2015 | 5 | Jadeveon Clowney | LB | Shoulder / Knee | Probable |
| 2015 | 5 | Arian Foster | RB | Groin | Probable |
| 2015 | 5 | Johnathan Joseph | CB | Hip | Probable |
| 2015 | 5 | Eddie Pleasant | S | Thigh | Probable |
| 2015 | 6 | Jadeveon Clowney | LB | Ankle | Out |
| 2015 | 6 | Quintin Demps | S | Hamstring | Out |
| 2015 | 6 | Nate Washington | WR | Hamstring | Out |
| 2015 | 6 | Brian Peters | LB | Hamstring | Questionable |
| 2015 | 6 | Jaelen Strong | WR | Illness | Questionable |
| 2015 | 6 | Jared Crick | DE | Knee | Questionable |
| 2015 | 6 | Alfred Blue | RB | Toe | Questionable |
| 2015 | 6 | Oday Aboushi | G | Toe | Probable |
| 2015 | 6 | Lonnie Ballentine | S | Knee | Probable |
| 2015 | 6 | A.J. Bouye | CB | Illness | Probable |
| 2015 | 6 | Duane Brown | T | Hand | Probable |
| 2015 | 6 | Brian Cushing | LB | Ankle | Probable |
| 2015 | 6 | C.J. Fiedorowicz | TE | Neck | Probable |
| 2015 | 6 | Arian Foster | RB | Groin | Probable |
| 2015 | 6 | Jonathan Grimes | RB | Hamstring | Probable |
| 2015 | 6 | Kareem Jackson | CB | Not Injury Related | Probable |
| 2015 | 6 | Derek Newton | T | Knee | Probable |
| 2015 | 6 | Chris Polk | RB | Knee | Probable |
| 2015 | 6 | Akeem Dent | LB | Hamstring | Probable |
| 2015 | 6 | Cecil Shorts | WR | Shoulder | Probable |
| 2015 | 7 | Kareem Jackson | CB | Ankle | Out |
| 2015 | 7 | Benardrick McKinney | LB | Concussion | Out |
| 2015 | 7 | Cecil Shorts | WR | Hamstring | Out |
| 2015 | 7 | Brandon Brooks | G | Toe | Questionable |
| 2015 | 7 | Jadeveon Clowney | LB | Ankle | Questionable |
| 2015 | 7 | Quintin Demps | S | Hamstring | Questionable |
| 2015 | 7 | Oday Aboushi | G | Toe | Probable |
| 2015 | 7 | Alfred Blue | RB | Toe | Probable |
| 2015 | 7 | Duane Brown | T | Hand | Probable |
| 2015 | 7 | Brian Cushing | LB | Ankle | Probable |
| 2015 | 7 | Akeem Dent | LB | Hamstring | Probable |
| 2015 | 7 | Arian Foster | RB | Groin | Probable |
| 2015 | 7 | Jonathan Grimes | RB | Hamstring | Probable |
| 2015 | 7 | Andre Hal | S | Shin | Probable |
| 2015 | 7 | Ben Jones | C | Toe | Probable |
| 2015 | 7 | Derek Newton | T | Knee / Toe | Probable |
| 2015 | 7 | Brian Peters | LB | Hamstring | Probable |
| 2015 | 7 | Chris Polk | RB | Knee | Probable |
| 2015 | 7 | Nate Washington | WR | Hamstring | Probable |
| 2015 | 8 | Akeem Dent | LB | Hamstring | Out |
| 2015 | 8 | Kareem Jackson | CB | Ankle | Out |
| 2015 | 8 | Greg Mancz | C | Knee | Out |
| 2015 | 8 | Benardrick McKinney | LB | Concussion | Out |
| 2015 | 8 | Cecil Shorts | WR | Hamstring | Out |
| 2015 | 8 | Brandon Brooks | G | Toe | Questionable |
| 2015 | 8 | Charles James | CB | Foot | Questionable |
| 2015 | 8 | J.J. Watt | DE | Back | Questionable |
| 2015 | 8 | Quintin Demps | S | Hamstring | Probable |
| 2015 | 8 | Ben Jones | C | Thumb | Probable |
| 2015 | 8 | Chris Polk | RB | Knee | Probable |
| 2015 | 8 | Jay Prosch | RB | Knee | Probable |
| 2015 | 8 | Jadeveon Clowney | LB | Illness / Ankle | Probable |
| 2015 | 8 | Derek Newton | T | Toe | Probable |
| 2015 | 10 | Jadeveon Clowney | LB | Back | Out |
| 2015 | 10 | Kareem Jackson | CB | Ankle | Out |
| 2015 | 10 | Duane Brown | T | Concussion | Probable |
| 2015 | 10 | Max Bullough | LB | Shoulder | Probable |
| 2015 | 10 | Akeem Dent | LB | Hamstring | Probable |
| 2015 | 10 | Kurtis Drummond | S | Concussion | Probable |
| 2015 | 10 | Charles James | CB | Foot | Probable |
| 2015 | 10 | Ben Jones | C | Thumb | Probable |
| 2015 | 10 | Benardrick McKinney | LB | Concussion | Probable |
| 2015 | 10 | Derek Newton | T | Knee | Probable |
| 2015 | 10 | Chris Polk | RB | Knee | Probable |
| 2015 | 10 | Cecil Shorts | WR | Hamstring | Probable |
| 2015 | 10 | Nate Washington | WR | Hip | Probable |
| 2015 | 11 | Brian Hoyer | QB | Concussion | Out |
| 2015 | 11 | Kareem Jackson | CB | Ankle | Out |
| 2015 | 11 | Akeem Dent | LB | Hamstring | Questionable |
| 2015 | 11 | Chris Polk | RB | Hamstring | Questionable |
| 2015 | 11 | Brian Cushing | LB | Not Injury Related | Probable |
| 2015 | 11 | Jadeveon Clowney | LB | Back | Probable |
| 2015 | 11 | Jared Crick | DE | Ankle | Probable |
| 2015 | 11 | Charles James | CB | Foot | Probable |
| 2015 | 11 | Kevin Johnson | CB | Thigh | Probable |
| 2015 | 11 | Ben Jones | C | Thumb | Probable |
| 2015 | 11 | Johnathan Joseph | CB | Calf | Probable |
| 2015 | 11 | Nick Novak | K | right Thigh | Probable |
| 2015 | 11 | Brian Peters | LB | Hamstring | Probable |
| 2015 | 11 | Nate Washington | WR | Hip | Probable |
| 2015 | 11 | Max Bullough | LB | Shoulder / Hamstring | Probable |
| 2015 | 11 | DeAndre Hopkins | WR | Knee | Probable |
| 2015 | 12 | A.J. Bouye | CB | Concussion | Probable |
| 2015 | 12 | Max Bullough | LB | Shoulder / Hamstring | Probable |
| 2015 | 12 | Jadeveon Clowney | LB | Wrist | Probable |
| 2015 | 12 | Christian Covington | DT | Hip | Probable |
| 2015 | 12 | Akeem Dent | LB | Hamstring | Probable |
| 2015 | 12 | Brian Hoyer | QB | Concussion | Probable |
| 2015 | 12 | Kareem Jackson | CB | Ankle | Probable |
| 2015 | 12 | Charles James | CB | Foot | Probable |
| 2015 | 12 | Ben Jones | C | Hand | Probable |
| 2015 | 12 | Whitney Mercilus | LB | Back | Probable |
| 2015 | 12 | Eddie Pleasant | S | Neck | Probable |
| 2015 | 12 | Chris Polk | RB | Knee / Hamstring | Probable |
| 2015 | 12 | Nate Washington | WR | Hip | Probable |
| 2015 | 12 | Alfred Blue | RB | Back | Probable |
| 2015 | 12 | Johnathan Joseph | CB | Knee / Wrist | Probable |
| 2015 | 12 | Derek Newton | T | Elbow | Probable |
| 2015 | 13 | Max Bullough | LB | Shoulder / Hamstring | Probable |
| 2015 | 13 | Akeem Dent | LB | Hamstring | Probable |
| 2015 | 13 | DeAndre Hopkins | WR | Hamstring | Probable |
| 2015 | 13 | Kareem Jackson | CB | Ankle | Probable |
| 2015 | 13 | Charles James | CB | Foot | Probable |
| 2015 | 13 | Ben Jones | C | Hand | Probable |
| 2015 | 13 | Johnathan Joseph | CB | Knee | Probable |
| 2015 | 13 | Whitney Mercilus | LB | Back | Probable |
| 2015 | 13 | Derek Newton | T | Elbow | Probable |
| 2015 | 13 | John Simon | LB | Groin | Probable |
| 2015 | 13 | Xavier Su'a-Filo | G | Shoulder | Probable |
| 2015 | 13 | Alfred Blue | RB | Back | Probable |
| 2015 | 13 | J.J. Watt | DE | Groin | Probable |
| 2015 | 14 | J.J. Watt | DE | Groin / Hand | Probable |
| 2015 | 14 | Alfred Blue | RB | Back | Probable |
| 2015 | 14 | Brandon Brooks | G | Illness / Toe | Probable |
| 2015 | 14 | Duane Brown | T | Knee | Probable |
| 2015 | 14 | Max Bullough | LB | Shoulder | Probable |
| 2015 | 14 | Jadeveon Clowney | LB | Hamstring | Probable |
| 2015 | 14 | Christian Covington | DT | Knee | Probable |
| 2015 | 14 | Kareem Jackson | CB | Ankle | Probable |
| 2015 | 14 | Charles James | CB | Calf | Probable |
| 2015 | 14 | Ben Jones | C | Hip | Probable |
| 2015 | 14 | Johnathan Joseph | CB | Knee | Probable |
| 2015 | 14 | Whitney Mercilus | LB | Back | Probable |
| 2015 | 14 | Derek Newton | T | Elbow / Knee | Probable |
| 2015 | 14 | Chris Polk | RB | Knee | Probable |
| 2015 | 14 | Cecil Shorts | WR | Hamstring | Probable |
| 2015 | 14 | DeAndre Hopkins | WR | Hamstring | Probable |
| 2015 | 15 | Christian Covington | DT | Ankle | Out |
| 2015 | 15 | Brian Hoyer | QB | Concussion | Out |
| 2015 | 15 | Alfred Blue | RB | Back | Probable |
| 2015 | 15 | Max Bullough | LB | Shoulder | Probable |
| 2015 | 15 | Brian Cushing | LB | Hip | Probable |
| 2015 | 15 | Quintin Demps | S | Groin | Probable |
| 2015 | 15 | Ryan Griffin | TE | Ankle | Probable |
| 2015 | 15 | Kareem Jackson | CB | Ankle | Probable |
| 2015 | 15 | Ben Jones | C | Hand | Probable |
| 2015 | 15 | Whitney Mercilus | LB | Back | Probable |
| 2015 | 15 | Chris Polk | RB | Knee | Probable |
| 2015 | 15 | Jadeveon Clowney | LB | Hamstring | Probable |
| 2015 | 15 | J.J. Watt | DE | Hand | Probable |
| 2015 | 16 | Rahim Moore | S | Illness | Out |
| 2015 | 16 | Cecil Shorts | WR | Hamstring | Out |
| 2015 | 16 | Jared Crick | DE | Back | Questionable |
| 2015 | 16 | Brian Hoyer | QB | Concussion / Ankle | Questionable |
| 2015 | 16 | Alfred Blue | RB | Back | Probable |
| 2015 | 16 | Max Bullough | LB | Shoulder | Probable |
| 2015 | 16 | Jadeveon Clowney | LB | Hamstring | Probable |
| 2015 | 16 | Christian Covington | DT | Ankle | Probable |
| 2015 | 16 | B.J. Daniels | QB | Chest | Probable |
| 2015 | 16 | Kareem Jackson | CB | Ankle | Probable |
| 2015 | 16 | Ben Jones | C | Hand / Ankle | Probable |
| 2015 | 16 | Whitney Mercilus | LB | Back | Probable |
| 2015 | 16 | Chris Polk | RB | Knee | Probable |
| 2015 | 16 | Xavier Su'a-Filo | G | Calf | Probable |
| 2015 | 16 | J.J. Watt | DE | Hand / Groin | Probable |
| 2015 | 16 | Ryan Griffin | TE | Achilles | Probable |
| 2015 | 16 | Derek Newton | T | Elbow | Probable |
| 2015 | 17 | Jadeveon Clowney | LB | Foot | Out |
| 2015 | 17 | Cecil Shorts | WR | Hamstring | Out |
| 2015 | 17 | Jeoffrey Pagan | DE | Illness | Questionable |
| 2015 | 17 | Alfred Blue | RB | Calf | Probable |
| 2015 | 17 | A.J. Bouye | CB | Knee | Probable |
| 2015 | 17 | Max Bullough | LB | Shoulder | Probable |
| 2015 | 17 | Jared Crick | DE | Back | Probable |
| 2015 | 17 | B.J. Daniels | WR | Chest | Probable |
| 2015 | 17 | Brian Hoyer | QB | Concussion / Ankle | Probable |
| 2015 | 17 | Kareem Jackson | CB | Ankle | Probable |
| 2015 | 17 | Kevin Johnson | CB | Foot | Probable |
| 2015 | 17 | Whitney Mercilus | LB | Back | Probable |
| 2015 | 17 | Rahim Moore | S | Illness | Probable |
| 2015 | 17 | Chris Polk | RB | Knee | Probable |
| 2015 | 17 | Xavier Su'a-Filo | G | Calf | Probable |
| 2015 | 17 | J.J. Watt | DE | Groin / Hand | Probable |
| 2015 | 17 | Ryan Griffin | TE | Achilles | Probable |
| 2015 | 17 | Ben Jones | C | Ankle | Probable |
| 2015 | 17 | Derek Newton | T | Elbow | Probable |
| 2015 | 17 | Brian Peters | LB | Chest | Probable |
| 2015 | 18 (WC) | Jadeveon Clowney | LB | Foot | Questionable |
| 2015 | 18 (WC) | A.J. Bouye | CB | Knee | Probable |
| 2015 | 18 (WC) | Max Bullough | LB | Shoulder | Probable |
| 2015 | 18 (WC) | Quintin Demps | S | Shoulder | Probable |
| 2015 | 18 (WC) | Ryan Griffin | TE | Achilles | Probable |
| 2015 | 18 (WC) | DeAndre Hopkins | WR | Hand | Probable |
| 2015 | 18 (WC) | Kareem Jackson | CB | Ankle | Probable |
| 2015 | 18 (WC) | Ben Jones | C | Knee | Probable |
| 2015 | 18 (WC) | Whitney Mercilus | LB | Back | Probable |
| 2015 | 18 (WC) | Chris Polk | RB | Knee | Probable |
| 2015 | 18 (WC) | Cecil Shorts | WR | Hamstring | Probable |
| 2015 | 18 (WC) | John Simon | LB | Chest | Probable |
| 2015 | 18 (WC) | Xavier Su'a-Filo | G | Calf | Probable |
| 2015 | 18 (WC) | Alfred Blue | RB | Calf | Probable |
| 2015 | 18 (WC) | Kevin Johnson | CB | Foot / Wrist | Probable |
| 2015 | 18 (WC) | Shane Lechler | P | left Hamstring | Probable |
| 2015 | 18 (WC) | Derek Newton | T | Elbow / Shoulder | Probable |
| 2015 | 18 (WC) | Nate Washington | WR | Hip | Probable |
| 2015 | 18 (WC) | J.J. Watt | DE | Groin / Hand | Probable |
| 2016 | 1 | Akeem Dent | LB | Concussion | — |
| 2016 | 1 | Will Fuller | WR | Hamstring | — |
| 2016 | 1 | Derek Newton | T | Hamstring | — |
| 2016 | 1 | J.J. Watt | DE | Back | — |
| 2016 | 1 | Duane Brown | T | Knee | Out |
| 2016 | 2 | Jay Prosch | RB | Ankle | — |
| 2016 | 2 | John Simon | LB | Wrist | — |
| 2016 | 2 | J.J. Watt | DE | Back | — |
| 2016 | 2 | Duane Brown | T | Knee | Out |
| 2016 | 2 | Brian Cushing | LB | Knee | Out |
| 2016 | 2 | Christian Covington | DE | Groin | Questionable |
| 2016 | 2 | Derek Newton | T | Knee | Questionable |
| 2016 | 2 | Jeff Allen | G | Calf | Questionable |
| 2016 | 3 | Jeff Allen | G | Calf | — |
| 2016 | 3 | A.J. Bouye | CB | Shoulder | — |
| 2016 | 3 | Chris Clark | T | Elbow / Ankle | — |
| 2016 | 3 | Jadeveon Clowney | LB | Foot | — |
| 2016 | 3 | Christian Covington | DE | Groin | — |
| 2016 | 3 | Kevin Johnson | CB | Thumb | — |
| 2016 | 3 | Derek Newton | T | Knee | — |
| 2016 | 3 | Brock Osweiler | QB | Back | — |
| 2016 | 3 | Jay Prosch | RB | Back | — |
| 2016 | 3 | John Simon | LB | Wrist | — |
| 2016 | 3 | Shane Lechler | P | Back | — |
| 2016 | 3 | J.J. Watt | DE | Back | — |
| 2016 | 3 | Duane Brown | T | Knee | Out |
| 2016 | 3 | Brian Cushing | LB | Knee | Out |
| 2016 | 3 | Braxton Miller | WR | Hamstring | Out |
| 2016 | 4 | Jeff Allen | G | Knee | — |
| 2016 | 4 | Christian Covington | DE | Wrist | — |
| 2016 | 4 | Kareem Jackson | CB | Neck | — |
| 2016 | 4 | Derek Newton | T | Knee | — |
| 2016 | 4 | Brennan Scarlett | LB | Wrist | — |
| 2016 | 4 | John Simon | LB | Wrist | — |
| 2016 | 4 | Stephen Anderson | TE | Hamstring | Out |
| 2016 | 4 | Jonathan Grimes | RB | Ankle | Out |
| 2016 | 4 | Braxton Miller | WR | Hamstring | Out |
| 2016 | 4 | Duane Brown | T | Knee | Out |
| 2016 | 4 | Brian Cushing | LB | Knee | Questionable |
| 2016 | 4 | Quintin Demps | S | Hamstring | Questionable |
| 2016 | 5 | Max Bullough | LB | Illness | — |
| 2016 | 5 | Brian Cushing | LB | Knee | — |
| 2016 | 5 | Charles James | CB | Hand | — |
| 2016 | 5 | Braxton Miller | WR | Hamstring | — |
| 2016 | 5 | John Simon | LB | Wrist | — |
| 2016 | 5 | Oday Aboushi | G | Toe | — |
| 2016 | 5 | C.J. Fiedorowicz | TE | Knee | — |
| 2016 | 5 | Derek Newton | T | Knee | — |
| 2016 | 5 | Stephen Anderson | TE | Hamstring | Out |
| 2016 | 5 | Jonathan Grimes | RB | Ankle | Out |
| 2016 | 5 | Duane Brown | T | Knee | Questionable |
| 2016 | 5 | Kareem Jackson | CB | Hamstring | Questionable |
| 2016 | 6 | Oday Aboushi | G | Toe | — |
| 2016 | 6 | C.J. Fiedorowicz | TE | Ankle | — |
| 2016 | 6 | Ryan Griffin | TE | Concussion | — |
| 2016 | 6 | Charles James | CB | Hand | — |
| 2016 | 6 | Kevin Johnson | CB | Ankle | — |
| 2016 | 6 | Johnathan Joseph | CB | Concussion | — |
| 2016 | 6 | Greg Mancz | C | Shoulder | — |
| 2016 | 6 | Braxton Miller | WR | Hamstring | — |
| 2016 | 6 | Xavier Su'a-Filo | G | Knee | — |
| 2016 | 6 | Duane Brown | T | Knee | — |
| 2016 | 6 | Jeff Allen | G | Concussion | Out |
| 2016 | 6 | Stephen Anderson | TE | Hamstring | Out |
| 2016 | 6 | Quintin Demps | S | Calf | Out |
| 2016 | 6 | Jonathan Grimes | RB | Ankle | Out |
| 2016 | 6 | Brian Peters | LB | Quadricep | Out |
| 2016 | 6 | Will Fuller | WR | Hamstring | Questionable |
| 2016 | 6 | Kareem Jackson | CB | Hamstring | Questionable |
| 2016 | 6 | Derek Newton | T | Ankle | Questionable |
| 2016 | 7 | Jeff Allen | G | Concussion | — |
| 2016 | 7 | Stephen Anderson | TE | Hamstring | — |
| 2016 | 7 | Duane Brown | T | Knee | — |
| 2016 | 7 | Will Fuller | WR | Hamstring | — |
| 2016 | 7 | Ryan Griffin | TE | Ribs | — |
| 2016 | 7 | DeAndre Hopkins | WR | Hamstring | — |
| 2016 | 7 | Kareem Jackson | CB | Hamstring | — |
| 2016 | 7 | Johnathan Joseph | CB | Forearm | — |
| 2016 | 7 | Greg Mancz | C | Knee | — |
| 2016 | 7 | Braxton Miller | WR | Hamstring | — |
| 2016 | 7 | Derek Newton | T | Ankle / Knee | — |
| 2016 | 7 | Brock Osweiler | QB | Foot | — |
| 2016 | 7 | Xavier Su'a-Filo | G | Knee | — |
| 2016 | 7 | Oday Aboushi | G | Shoulder | — |
| 2016 | 7 | Jadeveon Clowney | LB | Wrist | — |
| 2016 | 7 | John Simon | LB | Shoulder | — |
| 2016 | 7 | Quintin Demps | S | Calf | Out |
| 2016 | 7 | Jonathan Grimes | RB | Ankle | Out |
| 2016 | 7 | Kevin Johnson | CB | Foot | Out |
| 2016 | 7 | Brian Peters | LB | Quadricep | Out |
| 2016 | 8 | Derek Newton | T | Knees | — |
| 2016 | 8 | Oday Aboushi | G | Shoulder | — |
| 2016 | 8 | Lonnie Ballentine | S | Knee / Oblique | — |
| 2016 | 8 | Tyler Ervin | RB | Knee | — |
| 2016 | 8 | Greg Mancz | C | Knee | — |
| 2016 | 8 | Corey Moore | S | Concussion | — |
| 2016 | 8 | Brock Osweiler | QB | Foot | — |
| 2016 | 8 | Brian Peters | LB | Quadricep | Out |
| 2016 | 8 | Jadeveon Clowney | LB | Elbow | Questionable |
| 2016 | 8 | Quintin Demps | S | Calf | Questionable |
| 2016 | 8 | Jonathan Grimes | RB | Ankle | Questionable |
| 2016 | 8 | Lamar Miller | RB | Shoulder | Questionable |
| 2016 | 10 | Alfred Blue | RB | Ribs | — |
| 2016 | 10 | Max Bullough | LB | Hamstring | — |
| 2016 | 10 | Jadeveon Clowney | LB | Elbow | — |
| 2016 | 10 | Christian Covington | DE | Foot | — |
| 2016 | 10 | Quintin Demps | S | Calf | — |
| 2016 | 10 | Lamar Miller | RB | Shoulder | — |
| 2016 | 10 | Lonnie Ballentine | S | groin, knee, ankle | Out |
| 2016 | 10 | Jaelen Strong | WR | Ankle | Out |
| 2016 | 10 | Jonathan Grimes | RB | Illness | Questionable |
| 2016 | 10 | Brian Peters | LB | Quadricep | Questionable |
| 2016 | 10 | Vince Wilfork | DT | Groin | Questionable |
| 2016 | 10 | A.J. Bouye | CB | Ankle | Questionable |
| 2016 | 10 | Will Fuller | WR | Knee | Questionable |
| 2016 | 11 | Oday Aboushi | G | Shoulder | — |
| 2016 | 11 | A.J. Bouye | CB | Ankle | — |
| 2016 | 11 | Duane Brown | T | Knee | — |
| 2016 | 11 | Chris Clark | T | Hip | — |
| 2016 | 11 | C.J. Fiedorowicz | TE | Neck | — |
| 2016 | 11 | Brian Peters | LB | Quadricep | — |
| 2016 | 11 | Eddie Pleasant | S | Neck | — |
| 2016 | 11 | John Simon | LB | Shoulder | — |
| 2016 | 11 | Xavier Su'a-Filo | G | Finger | — |
| 2016 | 11 | Jadeveon Clowney | DE | Wrist | — |
| 2016 | 11 | Lamar Miller | RB | Ankle | — |
| 2016 | 11 | Alfred Blue | RB | Calf | Out |
| 2016 | 11 | Jonathan Grimes | RB | Illness | Out |
| 2016 | 11 | Jaelen Strong | WR | Ankle | Out |
| 2016 | 11 | Jay Prosch | RB | Hamstring | Questionable |
| 2016 | 11 | Will Fuller | WR | Knee | Questionable |
| 2016 | 11 | Vince Wilfork | DT | Groin | Questionable |
| 2016 | 12 | A.J. Bouye | CB | Ankle | — |
| 2016 | 12 | Duane Brown | T | Knee | — |
| 2016 | 12 | Max Bullough | LB | Elbow | — |
| 2016 | 12 | Chris Clark | T | Hip | — |
| 2016 | 12 | C.J. Fiedorowicz | TE | Shoulder | — |
| 2016 | 12 | Will Fuller | WR | Knee | — |
| 2016 | 12 | Ryan Griffin | TE | Neck | — |
| 2016 | 12 | Jonathan Grimes | RB | Illness | — |
| 2016 | 12 | Xavier Su'a-Filo | G | Finger | — |
| 2016 | 12 | Jadeveon Clowney | DE | Elbow / Wrist | — |
| 2016 | 12 | Lamar Miller | RB | Ankle / Ribs | — |
| 2016 | 12 | Vince Wilfork | DT | Groin | — |
| 2016 | 12 | Alfred Blue | RB | Calf | Out |
| 2016 | 12 | Tyler Ervin | RB | Ribs | Out |
| 2016 | 12 | John Simon | LB | Chest | Out |
| 2016 | 12 | Jaelen Strong | WR | Ankle | Out |
| 2016 | 12 | Jay Prosch | RB | Hamstring | Questionable |
| 2016 | 13 | A.J. Bouye | CB | Ankle | — |
| 2016 | 13 | Max Bullough | LB | Elbow | — |
| 2016 | 13 | Chris Clark | T | Shoulder / Hip | — |
| 2016 | 13 | C.J. Fiedorowicz | TE | Shoulder | — |
| 2016 | 13 | Will Fuller | WR | Knee | — |
| 2016 | 13 | Ryan Griffin | TE | Neck | — |
| 2016 | 13 | Kareem Jackson | CB | Hamstring | — |
| 2016 | 13 | Johnathan Joseph | CB | Shin | — |
| 2016 | 13 | Antonio Smith | DE | Hip | — |
| 2016 | 13 | Lamar Miller | RB | Ankle / Ribs | — |
| 2016 | 13 | Jay Prosch | RB | Hamstring | — |
| 2016 | 13 | D.J. Reader | DT | Shoulder | — |
| 2016 | 13 | Vince Wilfork | DT | Groin | — |
| 2016 | 13 | Tyler Ervin | RB | Ribs | Out |
| 2016 | 13 | John Simon | LB | Chest | Out |
| 2016 | 13 | Jaelen Strong | WR | Ankle | Out |
| 2016 | 13 | Andre Hal | S | Illness | Questionable |
| 2016 | 13 | Alfred Blue | RB | Calf | Questionable |
| 2016 | 13 | Jadeveon Clowney | DE | Elbow / Wrist | Questionable |
| 2016 | 13 | Brian Cushing | LB | Back | Questionable |
| 2016 | 14 | Christian Covington | DE | Thigh | — |
| 2016 | 14 | Will Fuller | WR | Hip | — |
| 2016 | 14 | Benardrick McKinney | LB | Thigh | — |
| 2016 | 14 | D.J. Reader | DT | Shoulder | — |
| 2016 | 14 | Xavier Su'a-Filo | G | Finger | — |
| 2016 | 14 | Vince Wilfork | DT | Groin | — |
| 2016 | 14 | Kareem Jackson | CB | Hamstring | — |
| 2016 | 14 | Lamar Miller | RB | Ankle / Ribs | — |
| 2016 | 14 | Tyler Ervin | RB | Ribs | Out |
| 2016 | 14 | Braxton Miller | WR | Shoulder | Out |
| 2016 | 14 | Tom Savage | QB | right Elbow | Out |
| 2016 | 14 | John Simon | LB | Chest | Out |
| 2016 | 14 | Jaelen Strong | WR | Ankle | Out |
| 2016 | 14 | Johnathan Joseph | CB | Ribs | Questionable |
| 2016 | 14 | Jadeveon Clowney | DE | Elbow / Wrist | Questionable |
| 2016 | 14 | Brian Cushing | LB | Back / Ankle | Questionable |
| 2016 | 15 | Kareem Jackson | CB | Hamstring | — |
| 2016 | 15 | Brock Osweiler | QB | Thigh | — |
| 2016 | 15 | Tom Savage | QB | right Elbow | — |
| 2016 | 15 | Antonio Smith | DE | Foot | — |
| 2016 | 15 | Xavier Su'a-Filo | G | Finger | — |
| 2016 | 15 | Chris Clark | T | Ankle | — |
| 2016 | 15 | Jadeveon Clowney | DE | Elbow / Wrist | — |
| 2016 | 15 | Brian Cushing | LB | Back / Ankle | — |
| 2016 | 15 | DeAndre Hopkins | WR | Hamstring | — |
| 2016 | 15 | Benardrick McKinney | LB | Wrist | — |
| 2016 | 15 | Lamar Miller | RB | Ankle / Ribs | — |
| 2016 | 15 | Jeff Allen | G | Concussion | Out |
| 2016 | 15 | C.J. Fiedorowicz | TE | Concussion | Out |
| 2016 | 15 | Don Jones | S | Illness | Out |
| 2016 | 15 | John Simon | LB | Chest | Out |
| 2016 | 15 | Whitney Mercilus | LB | Back | Questionable |
| 2016 | 15 | Tyler Ervin | RB | Ribs | Questionable |
| 2016 | 15 | Johnathan Joseph | CB | Ribs | Questionable |
| 2016 | 16 | Jeff Allen | G | Concussion | — |
| 2016 | 16 | Chris Clark | T | Ankle | — |
| 2016 | 16 | C.J. Fiedorowicz | TE | Concussion | — |
| 2016 | 16 | Ryan Griffin | TE | Hamstring | — |
| 2016 | 16 | Kareem Jackson | CB | Hamstring | — |
| 2016 | 16 | Don Jones | S | Illness | — |
| 2016 | 16 | Benardrick McKinney | LB | Wrist | — |
| 2016 | 16 | Whitney Mercilus | LB | Back | — |
| 2016 | 16 | Brian Peters | LB | Quadricep | — |
| 2016 | 16 | John Simon | LB | Chest | — |
| 2016 | 16 | Xavier Su'a-Filo | G | Finger | — |
| 2016 | 16 | Jadeveon Clowney | DE | Elbow / Wrist | — |
| 2016 | 16 | Brian Cushing | LB | Ankle | — |
| 2016 | 16 | Nick Novak | K | Oblique / Back | — |
| 2016 | 16 | Lamar Miller | RB | Ankle | Questionable |
| 2016 | 16 | Johnathan Joseph | CB | Ribs | Questionable |
| 2016 | 17 | Jeff Allen | G | Not Injury Related | — |
| 2016 | 17 | Quintin Demps | S | Achilles | — |
| 2016 | 17 | C.J. Fiedorowicz | TE | Thigh | — |
| 2016 | 17 | Benardrick McKinney | LB | Wrist | — |
| 2016 | 17 | Tom Savage | QB | Knee | — |
| 2016 | 17 | Kareem Jackson | CB | Neck | — |
| 2016 | 17 | Nick Novak | K | Oblique | — |
| 2016 | 17 | Jadeveon Clowney | DE | Elbow / Wrist | Out |
| 2016 | 17 | Lamar Miller | RB | Ankle | Out |
| 2016 | 17 | Jay Prosch | RB | Ankle / Knee | Out |
| 2016 | 17 | John Simon | LB | Chest | Out |
| 2016 | 17 | Johnathan Joseph | CB | Ribs / Shoulder / Illness | Questionable |
| 2016 | 17 | Brian Cushing | LB | Ankle | Questionable |
| 2016 | 18 (WC) | Jeff Allen | G | Ankle | — |
| 2016 | 18 (WC) | A.J. Bouye | CB | Groin | — |
| 2016 | 18 (WC) | Chris Clark | T | Ankle | — |
| 2016 | 18 (WC) | Jadeveon Clowney | DE | Elbow / Wrist | — |
| 2016 | 18 (WC) | Brian Cushing | LB | Ankle | — |
| 2016 | 18 (WC) | Quintin Demps | S | Hamstring | — |
| 2016 | 18 (WC) | Ryan Griffin | TE | Quadricep | — |
| 2016 | 18 (WC) | Andre Hal | S | Calf | — |
| 2016 | 18 (WC) | Kareem Jackson | CB | Neck | — |
| 2016 | 18 (WC) | Don Jones | S | Elbow | — |
| 2016 | 18 (WC) | Johnathan Joseph | CB | Ribs / Shoulder | — |
| 2016 | 18 (WC) | Lamar Miller | RB | Ankle | — |
| 2016 | 18 (WC) | Nick Novak | K | Shoulder | — |
| 2016 | 18 (WC) | Jay Prosch | RB | Ankle / Knee | — |
| 2016 | 18 (WC) | Tom Savage | QB | Concussion | Out |
| 2016 | 18 (WC) | John Simon | LB | Chest | Out |
| 2016 | 19 (DIV) | Jeff Allen | G | Ankle | — |
| 2016 | 19 (DIV) | Chris Clark | T | Ankle | — |
| 2016 | 19 (DIV) | Jadeveon Clowney | DE | Elbow / Wrist | — |
| 2016 | 19 (DIV) | Brian Cushing | LB | Ankle | — |
| 2016 | 19 (DIV) | Ryan Griffin | TE | Quadricep | — |
| 2016 | 19 (DIV) | Andre Hal | S | Foot | — |
| 2016 | 19 (DIV) | Johnathan Joseph | CB | Calf | — |
| 2016 | 19 (DIV) | Whitney Mercilus | LB | Knee | — |
| 2016 | 19 (DIV) | Brian Peters | LB | Foot | — |
| 2016 | 19 (DIV) | Tom Savage | QB | Concussion | — |
| 2016 | 19 (DIV) | A.J. Bouye | CB | Groin | — |
| 2016 | 19 (DIV) | DeAndre Hopkins | WR | Knee | — |
| 2016 | 19 (DIV) | Quintin Demps | S | Hamstring | Questionable |
| 2016 | 19 (DIV) | John Simon | LB | Chest | Questionable |
| 2017 | 1 | C.J. Fiedorowicz | TE | Concussion | — |
| 2017 | 1 | D'Onta Foreman | RB | Groin | — |
| 2017 | 1 | DeAndre Hopkins | WR | Thumb | — |
| 2017 | 1 | Braxton Miller | WR | Ankle | — |
| 2017 | 1 | Alfred Blue | RB | Ankle | Out |
| 2017 | 1 | Will Fuller | WR | Shoulder | Out |
| 2017 | 2 | C.J. Fiedorowicz | TE | Concussion | — |
| 2017 | 2 | Jadeveon Clowney | LB | Foot | — |
| 2017 | 2 | Brandon Dunn | DT | Abdomen | — |
| 2017 | 2 | Tyler Ervin | RB | Knee | — |
| 2017 | 2 | Breno Giacomini | T | Thigh | — |
| 2017 | 2 | Andre Hal | S | Hip | — |
| 2017 | 2 | Joel Heath | DE | Knee | — |
| 2017 | 2 | DeAndre Hopkins | WR | Wrist | — |
| 2017 | 2 | Nick Martin | C | Ankle | — |
| 2017 | 2 | Tom Savage | QB | left Finger | — |
| 2017 | 2 | Deshaun Watson | QB | Ankle | — |
| 2017 | 2 | J.J. Watt | DE | Finger | — |
| 2017 | 2 | Kevin Johnson | CB | Knee | — |
| 2017 | 2 | Benardrick McKinney | LB | Knee | — |
| 2017 | 2 | Jeff Allen | G | Ankle | Out |
| 2017 | 2 | Stephen Anderson | TE | Concussion | Out |
| 2017 | 2 | Alfred Blue | RB | Ankle | Out |
| 2017 | 2 | Brian Cushing | LB | Concussion | Out |
| 2017 | 2 | Bruce Ellington | WR | Concussion | Out |
| 2017 | 2 | Will Fuller | WR | Shoulder | Out |
| 2017 | 2 | Ryan Griffin | TE | Concussion | Out |
| 2017 | 3 | Stephen Anderson | TE | Concussion | — |
| 2017 | 3 | Marcus Burley | CB | Knee | — |
| 2017 | 3 | Chris Clark | T | Wrist | — |
| 2017 | 3 | Bruce Ellington | WR | Concussion | — |
| 2017 | 3 | Ryan Griffin | TE | Concussion | — |
| 2017 | 3 | Johnathan Joseph | CB | Shoulder | — |
| 2017 | 3 | Xavier Su'a-Filo | G | Knee | — |
| 2017 | 3 | J.J. Watt | DE | Finger | — |
| 2017 | 3 | Jeff Allen | G | Ankle | Out |
| 2017 | 3 | Kevin Johnson | CB | Knee | Out |
| 2017 | 3 | Will Fuller | WR | Shoulder | Out |
| 2017 | 3 | Alfred Blue | RB | Ankle | Questionable |
| 2017 | 3 | Brandon Dunn | DT | Knee | Questionable |
| 2017 | 4 | Jeff Allen | G | Ankle | — |
| 2017 | 4 | Alfred Blue | RB | Ankle | — |
| 2017 | 4 | Jadeveon Clowney | LB | Ankle | — |
| 2017 | 4 | Kurtis Drummond | S | Shoulder | — |
| 2017 | 4 | Brandon Dunn | DT | Knee | — |
| 2017 | 4 | Tyler Ervin | RB | Shoulder | — |
| 2017 | 4 | Will Fuller | WR | Shoulder | — |
| 2017 | 4 | DeAndre Hopkins | WR | Knee | — |
| 2017 | 4 | Kareem Jackson | CB | Hamstring | — |
| 2017 | 4 | Johnathan Joseph | CB | Shoulder | — |
| 2017 | 4 | Whitney Mercilus | LB | Hip | — |
| 2017 | 4 | D.J. Reader | DT | Knee | — |
| 2017 | 4 | Xavier Su'a-Filo | G | Knee | — |
| 2017 | 4 | J.J. Watt | DE | Finger | — |
| 2017 | 4 | Kevin Johnson | CB | Knee | Out |
| 2017 | 4 | Greg Mancz | C | Knee | Out |
| 2017 | 4 | Marcus Burley | CB | Knee | Questionable |
| 2017 | 5 | Marcus Burley | CB | Knee | — |
| 2017 | 5 | Christian Covington | DE | Knee | — |
| 2017 | 5 | Andre Hal | S | Ribs | — |
| 2017 | 5 | Kareem Jackson | CB | Hamstring | — |
| 2017 | 5 | Whitney Mercilus | LB | Ankle | — |
| 2017 | 5 | Jordan Todman | RB | Foot | — |
| 2017 | 5 | J.J. Watt | DE | Finger | — |
| 2017 | 5 | Xavier Su'a-Filo | G | Knee | — |
| 2017 | 5 | Kyle Fuller | G | Hamstring | Out |
| 2017 | 5 | Ben Heeney | LB | Knee | Out |
| 2017 | 5 | Kevin Johnson | CB | Knee | Out |
| 2017 | 5 | Greg Mancz | C | Knee | Questionable |
| 2017 | 6 | Marcus Burley | CB | Knee | — |
| 2017 | 6 | Dylan Cole | LB | Ankle | — |
| 2017 | 6 | D'Onta Foreman | RB | Hip | — |
| 2017 | 6 | Kyle Fuller | G | Hamstring | — |
| 2017 | 6 | Kareem Jackson | CB | Hamstring | — |
| 2017 | 6 | Brennan Scarlett | LB | Shoulder | — |
| 2017 | 6 | Xavier Su'a-Filo | G | Knee | — |
| 2017 | 6 | Chris Thompson | WR | Wrist | — |
| 2017 | 6 | Jonathan Weeks | LS | Knee | — |
| 2017 | 6 | Jadeveon Clowney | LB | Knee | — |
| 2017 | 6 | Johnathan Joseph | CB | Groin | — |
| 2017 | 6 | Ben Heeney | LB | Knee | Out |
| 2017 | 6 | Kevin Johnson | CB | Knee | Out |
| 2017 | 6 | Corey Moore | S | Concussion | Out |
| 2017 | 6 | Jordan Todman | RB | Calf | Out |
| 2017 | 6 | Greg Mancz | C | Knee | Questionable |
| 2017 | 6 | Benardrick McKinney | LB | Hip | Questionable |
| 2017 | 8 | D'Onta Foreman | RB | Not Injury Related | — |
| 2017 | 8 | DeAndre Hopkins | WR | Not Injury Related | — |
| 2017 | 8 | Ben Heeney | LB | Knee | — |
| 2017 | 8 | Kevin Johnson | CB | Knee | — |
| 2017 | 8 | Greg Mancz | C | Knee | — |
| 2017 | 8 | Corey Moore | S | Concussion | — |
| 2017 | 8 | Xavier Su'a-Filo | G | Knee | — |
| 2017 | 8 | Jordan Todman | RB | Calf | — |
| 2017 | 8 | Chris Clark | T | Calf | Out |
| 2017 | 8 | Dylan Cole | LB | Hamstring | Out |
| 2017 | 8 | Joel Heath | DE | Knee | Out |
| 2017 | 8 | Kendall Langford | DT | Back | Questionable |
| 2017 | 8 | Jelani Jenkins | LB | Hand | Questionable |
| 2017 | 9 | Jeff Allen | G | Knee | — |
| 2017 | 9 | Jadeveon Clowney | LB | Knee | — |
| 2017 | 9 | Ryan Griffin | TE | Hip | — |
| 2017 | 9 | Ben Heeney | LB | Knee / Elbow | — |
| 2017 | 9 | Lamarr Houston | LB | Knee | — |
| 2017 | 9 | Jelani Jenkins | LB | Hand | — |
| 2017 | 9 | Kevin Johnson | CB | Knee / Back | — |
| 2017 | 9 | Kendall Langford | DE | Back | — |
| 2017 | 9 | Greg Mancz | C | Knee | — |
| 2017 | 9 | Lamar Miller | RB | Knee | — |
| 2017 | 9 | Brian Peters | LB | Hamstring | — |
| 2017 | 9 | D.J. Reader | DT | Shoulder | — |
| 2017 | 9 | Chris Clark | T | Calf | — |
| 2017 | 9 | Deshaun Watson | QB | Knee | — |
| 2017 | 9 | Dylan Cole | LB | Hamstring | Out |
| 2017 | 9 | Joel Heath | DE | Knee | Out |
| 2017 | 9 | Johnathan Joseph | CB | Shin / Quadricep | Questionable |
| 2017 | 10 | Ryan Griffin | TE | Concussion | — |
| 2017 | 10 | Jeff Allen | G | Hand | — |
| 2017 | 10 | Jadeveon Clowney | LB | Knee | — |
| 2017 | 10 | Brandon Dunn | DT | Back | — |
| 2017 | 10 | Bruce Ellington | WR | Ribs | — |
| 2017 | 10 | Will Fuller | WR | Knee | — |
| 2017 | 10 | Marcus Gilchrist | S | Shoulder | — |
| 2017 | 10 | Ben Heeney | LB | Elbow | — |
| 2017 | 10 | Jelani Jenkins | LB | Hand | — |
| 2017 | 10 | Johnathan Joseph | CB | Knee | — |
| 2017 | 10 | Greg Mancz | C | Knee | — |
| 2017 | 10 | Chris Thompson | WR | Shoulder | — |
| 2017 | 10 | Carlos Watkins | DE | Knee | — |
| 2017 | 10 | Jonathan Weeks | LS | Knee | — |
| 2017 | 10 | Dylan Cole | LB | Hamstring | Out |
| 2017 | 10 | Joel Heath | DE | Knee | Out |
| 2017 | 11 | Jeff Allen | G | Hand | — |
| 2017 | 11 | Chris Clark | T | Shoulder | — |
| 2017 | 11 | Jadeveon Clowney | LB | Knee | — |
| 2017 | 11 | Brandon Dunn | DT | Shoulder | — |
| 2017 | 11 | Bruce Ellington | WR | Ribs | — |
| 2017 | 11 | Ben Heeney | LB | Elbow | — |
| 2017 | 11 | Kareem Jackson | CB | Shoulder | — |
| 2017 | 11 | Jelani Jenkins | LB | Hand | — |
| 2017 | 11 | Johnathan Joseph | CB | Knee | — |
| 2017 | 11 | Tom Savage | QB | right Shoulder | — |
| 2017 | 11 | Brennan Scarlett | LB | Knee | — |
| 2017 | 11 | Carlos Watkins | DE | Not Injury Related | — |
| 2017 | 11 | Dylan Cole | LB | Hamstring | Out |
| 2017 | 11 | Julien Davenport | T | Shoulder | Out |
| 2017 | 11 | Will Fuller | WR | Ribs | Out |
| 2017 | 11 | Alfred Blue | RB | Hamstring | Questionable |
| 2017 | 11 | Greg Mancz | C | Knee / Chest | Questionable |
| 2017 | 11 | Chris Thompson | WR | Knee | Questionable |
| 2017 | 11 | Joel Heath | DE | Knee | Questionable |
| 2017 | 12 | Jeff Allen | G | Hand | — |
| 2017 | 12 | Alfred Blue | RB | Hamstring | — |
| 2017 | 12 | Chris Clark | T | Knee | — |
| 2017 | 12 | Jadeveon Clowney | LB | Ankle | — |
| 2017 | 12 | Dylan Cole | LB | Hamstring | — |
| 2017 | 12 | Bruce Ellington | WR | Ribs | — |
| 2017 | 12 | Andre Hal | S | Knee | — |
| 2017 | 12 | Joel Heath | DE | Illness / Knee | — |
| 2017 | 12 | DeAndre Hopkins | WR | Foot | — |
| 2017 | 12 | Kareem Jackson | CB | Shoulder | — |
| 2017 | 12 | Jelani Jenkins | LB | Hand | — |
| 2017 | 12 | Kevin Johnson | CB | Concussion | — |
| 2017 | 12 | Chris Thompson | WR | Knee | — |
| 2017 | 12 | Julien Davenport | T | Shoulder | Out |
| 2017 | 12 | Will Fuller | WR | Ribs | Out |
| 2017 | 12 | Greg Mancz | C | Shoulder | Out |
| 2017 | 13 | Jeff Allen | G | Hand | — |
| 2017 | 13 | DeAndre Hopkins | WR | Foot | — |
| 2017 | 13 | Kareem Jackson | CB | Shoulder | — |
| 2017 | 13 | Greg Mancz | G | Shoulder | — |
| 2017 | 13 | Jadeveon Clowney | LB | Shoulder / Ankle | — |
| 2017 | 13 | Bruce Ellington | WR | Knee | — |
| 2017 | 13 | Lamar Miller | RB | Knee | — |
| 2017 | 13 | Julien Davenport | T | Shoulder | Out |
| 2017 | 13 | Will Fuller | WR | Ribs | Out |
| 2017 | 13 | Brennan Scarlett | LB | Foot | Out |
| 2017 | 14 | Jeff Allen | G | Hand | — |
| 2017 | 14 | Jadeveon Clowney | LB | Knee | — |
| 2017 | 14 | Will Fuller | WR | Ribs | — |
| 2017 | 14 | Kareem Jackson | CB | Ribs | — |
| 2017 | 14 | Johnathan Joseph | CB | Shoulder | — |
| 2017 | 14 | Greg Mancz | G | Shoulder | — |
| 2017 | 14 | Chris Thompson | WR | Neck | — |
| 2017 | 14 | Jordan Todman | RB | Hand | — |
| 2017 | 14 | Alfred Blue | RB | Concussion | Out |
| 2017 | 14 | Julien Davenport | T | Shoulder | Out |
| 2017 | 14 | Jelani Jenkins | LB | Concussion | Out |
| 2017 | 14 | Braxton Miller | WR | Concussion | Out |
| 2017 | 14 | Xavier Su'a-Filo | G | Groin | Questionable |
| 2017 | 15 | Alfred Blue | RB | Concussion | — |
| 2017 | 15 | Brandon Dunn | DT | Back | — |
| 2017 | 15 | Andre Ellington | RB | Knee | — |
| 2017 | 15 | Andre Hal | S | Knee | — |
| 2017 | 15 | Johnathan Joseph | CB | Illness | — |
| 2017 | 15 | Greg Mancz | G | Knee | — |
| 2017 | 15 | Lamar Miller | RB | Knee | — |
| 2017 | 15 | Jordan Todman | RB | Hand | — |
| 2017 | 15 | DeAndrew White | WR | Thigh | — |
| 2017 | 15 | Jeff Allen | G | Groin | — |
| 2017 | 15 | Julien Davenport | T | Shoulder | — |
| 2017 | 15 | Joel Heath | DE | Knee | — |
| 2017 | 15 | Brian Peters | LB | Hamstring | — |
| 2017 | 15 | Xavier Su'a-Filo | G | Groin | — |
| 2017 | 15 | Jelani Jenkins | LB | Concussion | Out |
| 2017 | 15 | Kendall Lamm | T | Concussion | Out |
| 2017 | 15 | Braxton Miller | WR | Concussion | Out |
| 2017 | 15 | Tom Savage | QB | Concussion | Out |
| 2017 | 15 | Jadeveon Clowney | LB | Knee / Illness | Questionable |
| 2017 | 15 | DeAndre Hopkins | WR | Toe | Questionable |
| 2017 | 15 | MyCole Pruitt | TE | Calf | Questionable |
| 2017 | 16 | Tom Savage | QB | Concussion | — |
| 2017 | 16 | Julien Davenport | T | Shoulder | — |
| 2017 | 16 | Kurtis Drummond | S | Ankle | — |
| 2017 | 16 | Joel Heath | DE | Knee | — |
| 2017 | 16 | Jelani Jenkins | LB | Concussion | — |
| 2017 | 16 | Greg Mancz | G | Knee | — |
| 2017 | 16 | Braxton Miller | WR | Concussion | — |
| 2017 | 16 | Brian Peters | LB | Illness | — |
| 2017 | 16 | Carlos Watkins | DE | Knee | — |
| 2017 | 16 | T.J. Yates | QB | Knee | — |
| 2017 | 16 | Jadeveon Clowney | LB | Knee / Neck | — |
| 2017 | 16 | DeAndre Hopkins | WR | Toe | — |
| 2017 | 16 | Xavier Su'a-Filo | G | Groin | — |
| 2017 | 16 | Jeff Allen | G | Concussion | Out |
| 2017 | 16 | Kendall Lamm | T | Concussion | Out |
| 2017 | 16 | LaTroy Lewis | LB | Shoulder | Out |
| 2017 | 17 | Dylan Cole | LB | Elbow | — |
| 2017 | 17 | Julien Davenport | T | Shoulder | — |
| 2017 | 17 | Taylor Heinicke | QB | Concussion | — |
| 2017 | 17 | Greg Mancz | G | Knee | — |
| 2017 | 17 | Eddie Pleasant | S | Neck | — |
| 2017 | 17 | Jadeveon Clowney | LB | Knee / Toe | — |
| 2017 | 17 | Joel Heath | DE | Knee | — |
| 2017 | 17 | Kareem Jackson | CB | Foot | — |
| 2017 | 17 | Kevin Johnson | CB | Knee | — |
| 2017 | 17 | Xavier Su'a-Filo | G | Groin | — |
| 2017 | 17 | Jeff Allen | G | Concussion | Out |
| 2017 | 17 | DeAndre Hopkins | WR | Calf | Out |
| 2017 | 17 | Jordan Todman | RB | Shoulder | Out |
| 2017 | 17 | Kendall Lamm | T | Concussion | Questionable |
| 2017 | 17 | LaTroy Lewis | LB | Shoulder | Questionable |
| 2018 | 1 | Ka'imi Fairbairn | K | right Thigh | — |
| 2018 | 1 | Kevin Johnson | CB | Concussion | — |
| 2018 | 1 | Whitney Mercilus | LB | Hamstring | — |
| 2018 | 1 | Kayvon Webster | CB | Achilles | Out |
| 2018 | 1 | Sammie Coates | WR | Hamstring | Questionable |
| 2018 | 1 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 1 | Duke Ejiofor | LB | Hamstring | Questionable |
| 2018 | 1 | Will Fuller | WR | Hamstring | Questionable |
| 2018 | 2 | Kayvon Webster | CB | Achilles | Out |
| 2018 | 2 | Johnson Bademosi | CB | Knee | Questionable |
| 2018 | 2 | Jadeveon Clowney | LB | Back / Elbow | Questionable |
| 2018 | 2 | Sammie Coates | WR | Hamstring | Questionable |
| 2018 | 2 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 2 | Christian Covington | DE | Thigh / Knee | Questionable |
| 2018 | 2 | Duke Ejiofor | LB | Hamstring | Questionable |
| 2018 | 2 | Will Fuller | WR | Hamstring | Questionable |
| 2018 | 2 | DeAndre Hopkins | WR | Foot | Questionable |
| 2018 | 3 | Johnson Bademosi | CB | Knee | — |
| 2018 | 3 | Jadeveon Clowney | LB | Back | — |
| 2018 | 3 | Christian Covington | DE | Thigh / Knee | — |
| 2018 | 3 | Duke Ejiofor | LB | Hamstring | — |
| 2018 | 3 | Ryan Griffin | TE | Hip | — |
| 2018 | 3 | Kareem Jackson | CB | Ankle | — |
| 2018 | 3 | Whitney Mercilus | LB | Shoulder | — |
| 2018 | 3 | Martinas Rankin | T | Ankle | — |
| 2018 | 3 | J.J. Watt | DE | Knee | — |
| 2018 | 3 | Will Fuller | WR | Hamstring | — |
| 2018 | 3 | DeAndre Hopkins | WR | Thumb / Ankle, Hamstring | — |
| 2018 | 3 | Kayvon Webster | CB | Achilles | Out |
| 2018 | 3 | Sammie Coates | WR | Hamstring | Questionable |
| 2018 | 3 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 3 | Jordan Thomas | TE | Hip | Questionable |
| 2018 | 4 | Martinas Rankin | T | Ankle | — |
| 2018 | 4 | J.J. Watt | DE | Thigh | — |
| 2018 | 4 | Sammie Coates | WR | Hamstring | — |
| 2018 | 4 | Keke Coutee | WR | Hamstring | — |
| 2018 | 4 | Will Fuller | WR | Hamstring | — |
| 2018 | 4 | Senio Kelemete | G | Knee | — |
| 2018 | 4 | DeAndre Hopkins | WR | Thumb / Ankle, Hamstring | Questionable |
| 2018 | 4 | Kayvon Webster | CB | Achilles | Questionable |
| 2018 | 4 | Shareece Wright | CB | Shoulder | Questionable |
| 2018 | 5 | Jadeveon Clowney | LB | Foot | — |
| 2018 | 5 | Zach Fulton | G | Shoulder | — |
| 2018 | 5 | Kareem Jackson | CB | Thumb | — |
| 2018 | 5 | Johnathan Joseph | CB | Groin | — |
| 2018 | 5 | Senio Kelemete | G | Knee | — |
| 2018 | 5 | Kendall Lamm | T | Shoulder | — |
| 2018 | 5 | Nick Martin | C | Ankle | — |
| 2018 | 5 | J.J. Watt | DE | Thigh | — |
| 2018 | 5 | Kayvon Webster | CB | Achilles | — |
| 2018 | 5 | Sammie Coates | WR | Hamstring | — |
| 2018 | 5 | DeAndre Hopkins | WR | Thumb / Ankle, Hamstring | — |
| 2018 | 5 | Shareece Wright | CB | Shoulder | — |
| 2018 | 5 | Aaron Colvin | CB | Ankle | Out |
| 2018 | 5 | Brian Peters | LB | Ankle | Out |
| 2018 | 5 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 5 | Will Fuller | WR | Hamstring | Questionable |
| 2018 | 5 | Lamar Miller | RB | Chest | Questionable |
| 2018 | 6 | Jadeveon Clowney | LB | Illness | — |
| 2018 | 6 | Sammie Coates | WR | Hamstring | — |
| 2018 | 6 | Kareem Jackson | CB | Finger | — |
| 2018 | 6 | Lamar Miller | RB | Chest | — |
| 2018 | 6 | Brennan Scarlett | LB | Groin | — |
| 2018 | 6 | Shareece Wright | CB | Shoulder / Hand | — |
| 2018 | 6 | Keke Coutee | WR | Hamstring | — |
| 2018 | 6 | Will Fuller | WR | Hamstring | — |
| 2018 | 6 | Ryan Griffin | TE | Toe | — |
| 2018 | 6 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 6 | Johnathan Joseph | CB | Hip | — |
| 2018 | 6 | Aaron Colvin | CB | Ankle | Out |
| 2018 | 6 | Brian Peters | LB | Ankle | Out |
| 2018 | 6 | Deshaun Watson | QB | Chest | Questionable |
| 2018 | 7 | Joel Heath | DE | Knee | — |
| 2018 | 7 | Kareem Jackson | CB | Thigh | — |
| 2018 | 7 | Johnathan Joseph | CB | Shoulder | — |
| 2018 | 7 | Whitney Mercilus | LB | Ankle | — |
| 2018 | 7 | Lamar Miller | RB | Chest | — |
| 2018 | 7 | Deshaun Watson | QB | Chest | — |
| 2018 | 7 | Keke Coutee | WR | Hamstring | — |
| 2018 | 7 | Will Fuller | WR | Hip | — |
| 2018 | 7 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 7 | Aaron Colvin | CB | Ankle | Out |
| 2018 | 7 | Ryan Griffin | TE | Illness | Out |
| 2018 | 7 | Brian Peters | LB | Ankle | Out |
| 2018 | 7 | Shareece Wright | CB | Shoulder / Hand, Groin | Out |
| 2018 | 7 | Zach Fulton | G | Ankle | Questionable |
| 2018 | 8 | Will Fuller | WR | Hip | — |
| 2018 | 8 | Johnathan Joseph | CB | Hip | — |
| 2018 | 8 | Lamar Miller | RB | Chest | — |
| 2018 | 8 | Brennan Scarlett | LB | Groin | — |
| 2018 | 8 | Jordan Thomas | TE | Groin | — |
| 2018 | 8 | Deshaun Watson | QB | Chest | — |
| 2018 | 8 | J.J. Watt | DE | Knees | — |
| 2018 | 8 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 8 | Aaron Colvin | CB | Ankle | Out |
| 2018 | 8 | Keke Coutee | WR | Hamstring | Out |
| 2018 | 8 | Zach Fulton | G | Ankle | Out |
| 2018 | 8 | Ryan Griffin | TE | Illness | Out |
| 2018 | 8 | Andre Hal | S | Shoulder | Out |
| 2018 | 8 | Brian Peters | LB | Ankle | Out |
| 2018 | 8 | Shareece Wright | CB | Shoulder / Hand, Groin | Out |
| 2018 | 9 | Ryan Griffin | TE | Illness | — |
| 2018 | 9 | Peter Kalambayi | LB | Concussion | — |
| 2018 | 9 | Brennan Scarlett | LB | Groin | — |
| 2018 | 9 | Deshaun Watson | QB | Chest | — |
| 2018 | 9 | Zach Fulton | G | Ankle | — |
| 2018 | 9 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 9 | Josh Keyes | LB | Foot | — |
| 2018 | 9 | Brian Peters | LB | Ankle | — |
| 2018 | 9 | Shareece Wright | CB | Hand / Groin | — |
| 2018 | 9 | Zach Cunningham | LB | Knee | Out |
| 2018 | 9 | Jadeveon Clowney | LB | Groin | Questionable |
| 2018 | 9 | Aaron Colvin | CB | Ankle | Questionable |
| 2018 | 9 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 9 | Andre Hal | S | Shoulder | Questionable |
| 2018 | 9 | Johnathan Joseph | CB | Ankle / Knee | Questionable |
| 2018 | 11 | Brian Peters | LB | Ankle | — |
| 2018 | 11 | Andre Hal | S | Shoulder | — |
| 2018 | 11 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 11 | Whitney Mercilus | LB | Ankle | — |
| 2018 | 11 | Aaron Colvin | CB | Ankle | Questionable |
| 2018 | 11 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 11 | Zach Cunningham | LB | Knee | Questionable |
| 2018 | 11 | Duke Ejiofor | LB | Shoulder | Questionable |
| 2018 | 11 | Johnathan Joseph | CB | Ankle / Knee | Questionable |
| 2018 | 12 | Aaron Colvin | CB | Ankle | — |
| 2018 | 12 | Keke Coutee | WR | Hamstring | — |
| 2018 | 12 | Zach Cunningham | LB | Knee | — |
| 2018 | 12 | Julien Davenport | T | Shoulder | — |
| 2018 | 12 | Andre Hal | S | Shoulder | — |
| 2018 | 12 | Johnathan Joseph | CB | Ankle | — |
| 2018 | 12 | Whitney Mercilus | LB | Ankle | — |
| 2018 | 12 | Brian Peters | LB | Ankle | — |
| 2018 | 12 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 12 | J.J. Watt | DE | Knee | — |
| 2018 | 12 | Sammie Coates | WR | Illness | Questionable |
| 2018 | 12 | Duke Ejiofor | LB | Shoulder | Questionable |
| 2018 | 12 | Zach Fulton | G | Shoulder | Questionable |
| 2018 | 12 | Senio Kelemete | G | Ankle | Questionable |
| 2018 | 13 | Alfred Blue | RB | Thigh | — |
| 2018 | 13 | Dylan Cole | LB | Wrist / Knee | — |
| 2018 | 13 | Aaron Colvin | CB | Ankle | — |
| 2018 | 13 | Zach Cunningham | LB | Knee | — |
| 2018 | 13 | Duke Ejiofor | LB | Shoulder | — |
| 2018 | 13 | Whitney Mercilus | LB | Ankle | — |
| 2018 | 13 | Brian Peters | LB | Ankle | — |
| 2018 | 13 | Justin Reid | S | Knee | — |
| 2018 | 13 | Demaryius Thomas | WR | Wrist | — |
| 2018 | 13 | Jordan Thomas | TE | Hamstring | — |
| 2018 | 13 | Zach Fulton | G | Shoulder | — |
| 2018 | 13 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 13 | Kareem Jackson | CB | Groin | — |
| 2018 | 13 | Johnathan Joseph | CB | Ankle / Knee | — |
| 2018 | 13 | Senio Kelemete | G | Ankle | — |
| 2018 | 13 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 13 | J.J. Watt | DE | Knee | Questionable |
| 2018 | 14 | Dylan Cole | LB | Wrist / Ankle | — |
| 2018 | 14 | Aaron Colvin | CB | Ankle | — |
| 2018 | 14 | Zach Cunningham | LB | Knee | — |
| 2018 | 14 | D'Onta Foreman | RB | Achilles | — |
| 2018 | 14 | Senio Kelemete | G | Ankle | — |
| 2018 | 14 | Kendall Lamm | T | Concussion | — |
| 2018 | 14 | Brian Peters | LB | Ankle | — |
| 2018 | 14 | Justin Reid | S | Shoulder / Wrist | — |
| 2018 | 14 | Deshaun Watson | QB | right Shoulder | — |
| 2018 | 14 | Trevor Daniel | P | right Hip | — |
| 2018 | 14 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 14 | Kareem Jackson | CB | Groin | — |
| 2018 | 14 | J.J. Watt | DE | Knee | — |
| 2018 | 14 | Zach Fulton | G | Hand | Out |
| 2018 | 14 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 14 | Johnathan Joseph | CB | Neck / Shoulder | Questionable |
| 2018 | 14 | Brennan Scarlett | LB | Ankle | Questionable |
| 2018 | 15 | D'Onta Foreman | RB | Not Injury Related | — |
| 2018 | 15 | Benardrick McKinney | LB | Not Injury Related | — |
| 2018 | 15 | DeAndre Carter | WR | Concussion | — |
| 2018 | 15 | Dylan Cole | LB | Wrist / Knee | — |
| 2018 | 15 | Aaron Colvin | CB | Ankle | — |
| 2018 | 15 | Kareem Jackson | CB | Knee | — |
| 2018 | 15 | Johnathan Joseph | CB | Neck | — |
| 2018 | 15 | Greg Mancz | C | Knee | — |
| 2018 | 15 | Brian Peters | LB | Ankle | — |
| 2018 | 15 | Justin Reid | S | Shoulder / Wrist | — |
| 2018 | 15 | Deshaun Watson | QB | right Shoulder | — |
| 2018 | 15 | J.J. Watt | DE | Knee | — |
| 2018 | 15 | Shareece Wright | CB | Neck | — |
| 2018 | 15 | DeAndre Hopkins | WR | Foot | — |
| 2018 | 15 | Senio Kelemete | G | Elbow | — |
| 2018 | 15 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 15 | Zach Fulton | G | Hand | Questionable |
| 2018 | 15 | Andre Hal | S | Ankle | Questionable |
| 2018 | 16 | Dylan Cole | LB | Wrist / Knee | — |
| 2018 | 16 | Zach Fulton | G | Hand | — |
| 2018 | 16 | Kareem Jackson | CB | Knee | — |
| 2018 | 16 | Greg Mancz | C | Knee | — |
| 2018 | 16 | Brian Peters | LB | Ankle | — |
| 2018 | 16 | Justin Reid | S | Shoulder / Wrist | — |
| 2018 | 16 | J.J. Watt | DE | Knee | — |
| 2018 | 16 | Brandon Weeden | QB | Illness | — |
| 2018 | 16 | Andre Hal | S | Ankle | — |
| 2018 | 16 | Mike Tyson | CB | Concussion | Out |
| 2018 | 16 | Johnathan Joseph | CB | Hip / Illness | Questionable |
| 2018 | 16 | Senio Kelemete | G | Elbow / Rib, Illness | Questionable |
| 2018 | 16 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 16 | Brandon Dunn | DT | Ankle | Questionable |
| 2018 | 16 | DeAndre Hopkins | WR | Ankle | Questionable |
| 2018 | 16 | Lamar Miller | RB | Ankle | Questionable |
| 2018 | 17 | DeAndre Carter | WR | Knee | — |
| 2018 | 17 | Dylan Cole | LB | Wrist | — |
| 2018 | 17 | Christian Covington | DE | Knee | — |
| 2018 | 17 | Zach Fulton | G | Hand | — |
| 2018 | 17 | Andre Hal | S | Ankle | — |
| 2018 | 17 | Kareem Jackson | CB | Knee | — |
| 2018 | 17 | Senio Kelemete | G | Elbow / Rib | — |
| 2018 | 17 | Greg Mancz | C | Knee | — |
| 2018 | 17 | Benardrick McKinney | LB | Foot | — |
| 2018 | 17 | Lamar Miller | RB | Ankle | — |
| 2018 | 17 | Justin Reid | S | Shoulder / Wrist | — |
| 2018 | 17 | Mike Tyson | CB | Concussion | — |
| 2018 | 17 | Joe Webb | QB | Ankle | — |
| 2018 | 17 | DeAndre Hopkins | WR | Ankle | — |
| 2018 | 17 | J.J. Watt | DE | Knee | — |
| 2018 | 17 | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 17 | Brandon Dunn | DT | Ankle | Questionable |
| 2018 | 17 | Johnathan Joseph | CB | Neck | Questionable |
| 2018 | 18 (WC) | Mike Tyson | CB | Knee / Ankle | — |
| 2018 | 18 (WC) | Dylan Cole | LB | Wrist | — |
| 2018 | 18 (WC) | Brandon Dunn | DT | Ankle | — |
| 2018 | 18 (WC) | Zach Fulton | G | Hand | — |
| 2018 | 18 (WC) | Andre Hal | S | Ankle | — |
| 2018 | 18 (WC) | Johnathan Joseph | CB | Neck | — |
| 2018 | 18 (WC) | Senio Kelemete | G | Knee / Rib | — |
| 2018 | 18 (WC) | Benardrick McKinney | LB | Heel | — |
| 2018 | 18 (WC) | Justin Reid | S | Wrist | — |
| 2018 | 18 (WC) | DeAndre Hopkins | WR | Ankle | — |
| 2018 | 18 (WC) | J.J. Watt | DE | Elbow / Knee | — |
| 2018 | 18 (WC) | Keke Coutee | WR | Hamstring | Questionable |
| 2018 | 18 (WC) | Buddy Howell | RB | Hamstring | Questionable |
| 2019 | 1 | Zach Fulton | G | Toe | — |
| 2019 | 1 | Justin Reid | S | Shoulder | — |
| 2019 | 1 | Carlos Watkins | DE | Non-Football Injury | — |
| 2019 | 1 | Tytus Howard | T | Finger | Questionable |
| 2019 | 1 | Keke Coutee | WR | Ankle | Questionable |
| 2019 | 1 | Greg Mancz | C | Ankle | Questionable |
| 2019 | 2 | Keke Coutee | WR | Ankle | — |
| 2019 | 2 | Will Fuller | WR | Not Injury Related | — |
| 2019 | 2 | Tashaun Gipson | S | Wrist | — |
| 2019 | 2 | Tytus Howard | T | Finger | — |
| 2019 | 2 | Justin Reid | S | Shoulder | — |
| 2019 | 2 | Deshaun Watson | QB | Back | — |
| 2019 | 2 | DeAndre Hopkins | WR | Ribs | — |
| 2019 | 2 | Taiwan Jones | RB | Elbow / Hamstring | Questionable |
| 2019 | 2 | Senio Kelemete | G | Wrist | Questionable |
| 2019 | 2 | Greg Mancz | C | Ankle | Questionable |
| 2019 | 3 | Dylan Cole | LB | Back | — |
| 2019 | 3 | Will Fuller | WR | Not Injury Related | — |
| 2019 | 3 | Tashaun Gipson | S | Wrist | — |
| 2019 | 3 | DeAndre Hopkins | WR | Ribs | — |
| 2019 | 3 | Carlos Hyde | RB | Shoulder | — |
| 2019 | 3 | Greg Mancz | C | Ankle | — |
| 2019 | 3 | A.J. Moore | S | Knee | — |
| 2019 | 3 | Justin Reid | S | Shoulder | — |
| 2019 | 3 | Taiwan Jones | RB | Hamstring | Questionable |
| 2019 | 3 | Senio Kelemete | G | Wrist | Questionable |
| 2019 | 3 | Laremy Tunsil | T | Ankle | Questionable |
| 2019 | 4 | Angelo Blackson | DE | Toe | — |
| 2019 | 4 | Will Fuller | WR | Not Injury Related | — |
| 2019 | 4 | Tashaun Gipson | S | Wrist / Hip | — |
| 2019 | 4 | DeAndre Hopkins | WR | Not Injury Related | — |
| 2019 | 4 | Carlos Hyde | RB | Shoulder | — |
| 2019 | 4 | Taiwan Jones | RB | Hamstring | — |
| 2019 | 4 | Greg Mancz | C | Ankle | — |
| 2019 | 4 | Whitney Mercilus | LB | Shoulder | — |
| 2019 | 4 | Justin Reid | S | Shoulder | — |
| 2019 | 4 | Laremy Tunsil | T | Ankle / Toe | — |
| 2019 | 4 | Seantrel Henderson | T | Illness | Out |
| 2019 | 4 | Charles Omenihu | DE | Knee | Questionable |
| 2019 | 5 | Will Fuller | WR | Not Injury Related | — |
| 2019 | 5 | Zach Fulton | G | Back | — |
| 2019 | 5 | Seantrel Henderson | T | Illness | — |
| 2019 | 5 | DeAndre Hopkins | WR | Not Injury Related | — |
| 2019 | 5 | Carlos Hyde | RB | Shoulder | — |
| 2019 | 5 | Peter Kalambayi | LB | Hand | — |
| 2019 | 5 | Alex McGough | QB | Hamstring | — |
| 2019 | 5 | Charles Omenihu | DE | Knee | — |
| 2019 | 5 | Justin Reid | S | Shoulder | — |
| 2019 | 5 | Laremy Tunsil | T | Toe | — |
| 2019 | 5 | Greg Mancz | C | Concussion | Out |
| 2019 | 5 | Tashaun Gipson | S | Wrist / Hip | Questionable |
| 2019 | 5 | Lonnie Johnson | CB | Groin | Questionable |
| 2019 | 5 | Kenny Stills | WR | Hamstring / Ankle | Questionable |
| 2019 | 6 | Carlos Hyde | RB | Shoulder / Thigh | — |
| 2019 | 6 | Peter Kalambayi | LB | Hand | — |
| 2019 | 6 | A.J. Moore | S | Knee | — |
| 2019 | 6 | Tashaun Gipson | S | Wrist / Hip | — |
| 2019 | 6 | DeAndre Hopkins | WR | Not Injury Related / Resting Veteran | — |
| 2019 | 6 | Greg Mancz | C | Concussion | Out |
| 2019 | 6 | Taiwan Jones | RB | Hip | Questionable |
| 2019 | 6 | Johnathan Joseph | CB | Hamstring | Questionable |
| 2019 | 6 | Kenny Stills | WR | Hamstring | Questionable |
| 2019 | 7 | Zach Cunningham | LB | Knee | — |
| 2019 | 7 | Will Fuller | WR | Calf / Oblique | — |
| 2019 | 7 | DeAndre Hopkins | WR | Ribs | — |
| 2019 | 7 | Carlos Hyde | RB | Calf | — |
| 2019 | 7 | Taiwan Jones | RB | Hip | — |
| 2019 | 7 | Kenny Stills | WR | Hamstring | — |
| 2019 | 7 | Tytus Howard | T | Knee | Out |
| 2019 | 7 | Greg Mancz | C | Concussion | Out |
| 2019 | 7 | Tashaun Gipson | S | Hip / Wrist | Questionable |
| 2019 | 7 | Johnathan Joseph | CB | Hamstring | Questionable |
| 2019 | 7 | Bradley Roby | CB | Hamstring | Questionable |
| 2019 | 8 | Dylan Cole | LB | Hamstring / Knee | — |
| 2019 | 8 | Taiwan Jones | RB | Hip | — |
| 2019 | 8 | A.J. Moore | S | Knee | — |
| 2019 | 8 | Justin Reid | S | Shoulder | — |
| 2019 | 8 | Kenny Stills | WR | Ankle / Hamstring | — |
| 2019 | 8 | Jonathan Weeks | LS | Ankle | — |
| 2019 | 8 | Gareon Conley | CB | Not Injury Related / - Resting Veteran | — |
| 2019 | 8 | Will Fuller | WR | Hamstring | Out |
| 2019 | 8 | Tytus Howard | T | Knee | Out |
| 2019 | 8 | Greg Mancz | C | Concussion | Out |
| 2019 | 8 | Tashaun Gipson | S | Back / Hamstring, Wrist | Questionable |
| 2019 | 8 | Roderick Johnson | T | Neck | Questionable |
| 2019 | 8 | Johnathan Joseph | CB | Hamstring / Neck | Questionable |
| 2019 | 8 | Bradley Roby | CB | Hamstring | Questionable |
| 2019 | 9 | Dylan Cole | LB | Knee | — |
| 2019 | 9 | Gareon Conley | CB | Hamstring | — |
| 2019 | 9 | DeAndre Hopkins | WR | Thumb | — |
| 2019 | 9 | Roderick Johnson | T | Neck | — |
| 2019 | 9 | Taiwan Jones | RB | Hip | — |
| 2019 | 9 | Johnathan Joseph | CB | Neck | — |
| 2019 | 9 | A.J. Moore | S | Knee | — |
| 2019 | 9 | Charles Omenihu | DE | Knee | — |
| 2019 | 9 | Kenny Stills | WR | Hamstring | — |
| 2019 | 9 | Deshaun Watson | QB | Eye | — |
| 2019 | 9 | Jonathan Weeks | LS | Ankle | — |
| 2019 | 9 | Will Fuller | WR | Hamstring | Out |
| 2019 | 9 | Tashaun Gipson | S | Back / Wrist | Out |
| 2019 | 9 | Lonnie Johnson | CB | Concussion | Out |
| 2019 | 9 | Greg Mancz | C | Concussion | Out |
| 2019 | 9 | Bradley Roby | CB | Hamstring | Out |
| 2019 | 9 | Tytus Howard | T | Knee | Questionable |
| 2019 | 9 | Laremy Tunsil | T | Shoulder | Questionable |
| 2019 | 11 | Dylan Cole | LB | Knee | — |
| 2019 | 11 | Tytus Howard | T | Knee | — |
| 2019 | 11 | Will Fuller | WR | Hamstring | Questionable |
| 2019 | 11 | Tashaun Gipson | S | Back / Wrist | Questionable |
| 2019 | 11 | Bradley Roby | CB | Hamstring | Questionable |
| 2019 | 11 | Laremy Tunsil | T | Shoulder | Questionable |
| 2019 | 12 | Dylan Cole | LB | Knee | — |
| 2019 | 12 | Tytus Howard | T | Knee | — |
| 2019 | 12 | Deshaun Watson | QB | Ankle | — |
| 2019 | 12 | Mike Adams | S | Concussion | Out |
| 2019 | 12 | Lonnie Johnson | CB | Ankle | Out |
| 2019 | 12 | Justin Reid | S | Concussion / Shoulder | Out |
| 2019 | 12 | Will Fuller | WR | Hamstring | Questionable |
| 2019 | 12 | Tashaun Gipson | S | Back | Questionable |
| 2019 | 12 | Bradley Roby | CB | Hamstring | Questionable |
| 2019 | 13 | Mike Adams | S | Concussion | — |
| 2019 | 13 | Will Fuller | WR | Hamstring | — |
| 2019 | 13 | Lonnie Johnson | CB | Ankle | — |
| 2019 | 13 | Justin Reid | S | Concussion | — |
| 2019 | 13 | Bradley Roby | CB | Hamstring | — |
| 2019 | 13 | Carlos Watkins | DE | Hamstring | Out |
| 2019 | 13 | Tytus Howard | T | Knee | Doubtful |
| 2019 | 13 | Angelo Blackson | DE | Shoulder | Questionable |
| 2019 | 13 | Gareon Conley | CB | Hip | Questionable |
| 2019 | 13 | Brennan Scarlett | LB | Shoulder | Questionable |
| 2019 | 14 | Jordan Akins | TE | Knee | — |
| 2019 | 14 | Angelo Blackson | DE | Shoulder | — |
| 2019 | 14 | Taiwan Jones | RB | Hamstring | Out |
| 2019 | 14 | Gareon Conley | CB | Hip | Questionable |
| 2019 | 14 | Will Fuller | WR | Hamstring | Questionable |
| 2019 | 14 | Bradley Roby | CB | Hamstring / Toe | Questionable |
| 2019 | 14 | Brennan Scarlett | LB | Shoulder | Questionable |
| 2019 | 14 | Carlos Watkins | DE | Hamstring | Questionable |
| 2019 | 15 | Chris Clark | T | Hip | — |
| 2019 | 15 | Gareon Conley | CB | Hip | — |
| 2019 | 15 | Carlos Watkins | DE | Hamstring | — |
| 2019 | 15 | Will Fuller | WR | Hamstring | Questionable |
| 2019 | 15 | Taiwan Jones | RB | Hamstring | Questionable |
| 2019 | 15 | Brennan Scarlett | LB | Achilles / Shoulder | Questionable |
| 2019 | 16 | Darren Fells | TE | Hand | — |
| 2019 | 16 | DeAndre Hopkins | WR | Illness | — |
| 2019 | 16 | Jacob Martin | LB | Knee | Out |
| 2019 | 16 | Benardrick McKinney | LB | Concussion | Out |
| 2019 | 16 | Jahleel Addae | S | Achilles | Questionable |
| 2019 | 16 | Will Fuller | WR | Hamstring | Questionable |
| 2019 | 16 | Carlos Hyde | RB | Ankle | Questionable |
| 2019 | 16 | Taiwan Jones | RB | Hamstring | Questionable |
| 2019 | 16 | Brennan Scarlett | LB | Achilles / Shoulder | Questionable |
| 2019 | 17 | Benardrick McKinney | LB | Concussion | — |
| 2019 | 17 | Brennan Scarlett | LB | Achilles | — |
| 2019 | 17 | Will Fuller | WR | Groin | Out |
| 2019 | 17 | DeAndre Hopkins | WR | Illness | Questionable |
| 2019 | 17 | Jahleel Addae | S | Achilles | Questionable |
| 2019 | 17 | Jacob Martin | LB | Knee | Questionable |
| 2019 | 17 | Bradley Roby | CB | Hamstring | Questionable |
| 2019 | 17 | Kenny Stills | WR | Knee | Questionable |
| 2019 | 17 | Laremy Tunsil | T | Ankle | Questionable |
| 2019 | 17 | Deshaun Watson | QB | Back | Questionable |
| 2019 | 18 (WC) | Jacob Martin | LB | Knee | — |
| 2019 | 18 (WC) | Kenny Stills | WR | Knee | — |
| 2019 | 18 (WC) | Jordan Thomas | TE | Illness | — |
| 2019 | 18 (WC) | Laremy Tunsil | T | Ankle | — |
| 2019 | 18 (WC) | J.J. Watt | DE | Shoulder | — |
| 2019 | 18 (WC) | Jahleel Addae | S | Achilles | Questionable |
| 2019 | 18 (WC) | Jordan Akins | TE | Hamstring | Questionable |
| 2019 | 18 (WC) | Will Fuller | WR | Groin | Questionable |
| 2019 | 18 (WC) | Johnathan Joseph | CB | Hamstring | Questionable |
| 2019 | 18 (WC) | Bradley Roby | CB | Hamstring | Questionable |
| 2019 | 19 (DIV) | Chris Clark | T | Concussion | — |
| 2019 | 19 (DIV) | Jacob Martin | LB | Illness | — |
| 2019 | 19 (DIV) | A.J. Moore | S | Hip | — |
| 2019 | 19 (DIV) | J.J. Watt | DE | Shoulder | — |
| 2019 | 19 (DIV) | Jahleel Addae | S | Knee | Questionable |
| 2019 | 19 (DIV) | Jordan Akins | TE | Hamstring | Questionable |
| 2019 | 19 (DIV) | Keion Crossen | CB | Hamstring | Questionable |
| 2019 | 19 (DIV) | Darren Fells | TE | Hip | Questionable |
| 2019 | 19 (DIV) | Will Fuller | WR | Groin | Questionable |
| 2019 | 19 (DIV) | Johnathan Joseph | CB | Hamstring | Questionable |
| 2019 | 19 (DIV) | Kenny Stills | WR | Knee | Questionable |
| 2020 | 1 | Phillip Gaines | CB | Hamstring | — |
| 2020 | 1 | Lonnie Johnson | CB | Hip | — |
| 2020 | 1 | J.J. Watt | DE | Not Injury Related | — |
| 2020 | 1 | Brandin Cooks | WR | Quadricep | Questionable |
| 2020 | 1 | Cullen Gillaspia | RB | Hamstring | Questionable |
| 2020 | 1 | Jonathan Greenard | LB | Ankle | Questionable |
| 2020 | 2 | Will Fuller | WR | Not Injury Related | — |
| 2020 | 2 | Cullen Gillaspia | RB | Hamstring | — |
| 2020 | 2 | Jonathan Greenard | LB | Ankle | — |
| 2020 | 2 | J.J. Watt | DE | Hip | — |
| 2020 | 2 | Peter Kalambayi | LB | Hamstring | Questionable |
| 2020 | 2 | Brandin Cooks | WR | Quadricep | Questionable |
| 2020 | 2 | Tytus Howard | T | Ankle | Questionable |
| 2020 | 2 | Duke Johnson | RB | Ankle | Questionable |
| 2020 | 3 | Randall Cobb | WR | Not Injury Related | — |
| 2020 | 3 | J.J. Watt | DE | Groin / Not Injury Related | — |
| 2020 | 3 | Brandin Cooks | WR | Quadricep | — |
| 2020 | 3 | Cullen Gillaspia | RB | Concussion | — |
| 2020 | 3 | Tytus Howard | T | Ankle | — |
| 2020 | 3 | Laremy Tunsil | T | Elbow | — |
| 2020 | 3 | Duke Johnson | RB | Ankle | Questionable |
| 2020 | 3 | Peter Kalambayi | LB | Hamstring | Questionable |
| 2020 | 3 | Kenny Stills | WR | Illness | Questionable |
| 2020 | 4 | Zach Cunningham | LB | Groin | — |
| 2020 | 4 | Will Fuller | WR | Hamstring | — |
| 2020 | 4 | P.J. Hall | DT | Groin | — |
| 2020 | 4 | Duke Johnson | RB | Ankle | — |
| 2020 | 4 | Lonnie Johnson | CB | Illness | — |
| 2020 | 4 | Charles Omenihu | DE | Knee | — |
| 2020 | 4 | Cullen Gillaspia | RB | Hamstring | Questionable |
| 2020 | 4 | Peter Kalambayi | LB | Hamstring | Questionable |
| 2020 | 5 | Randall Cobb | WR | Not Injury Related | — |
| 2020 | 5 | Dylan Cole | LB | Knee | — |
| 2020 | 5 | Brandon Dunn | DT | Elbow | — |
| 2020 | 5 | Cullen Gillaspia | RB | Hamstring | — |
| 2020 | 5 | Laremy Tunsil | T | Shoulder | — |
| 2020 | 5 | Jordan Akins | TE | Ankle / Concussion | Questionable |
| 2020 | 5 | Keion Crossen | CB | Hamstring | Questionable |
| 2020 | 5 | Buddy Howell | RB | Hamstring | Questionable |
| 2020 | 5 | Peter Kalambayi | LB | Hamstring | Questionable |
| 2020 | 5 | Benardrick McKinney | LB | Shoulder | Questionable |
| 2020 | 6 | Keke Coutee | WR | Not Injury Related | — |
| 2020 | 6 | J.J. Watt | DE | Not Injury Related | — |
| 2020 | 6 | Dylan Cole | LB | Knee | — |
| 2020 | 6 | Jacob Martin | LB | Ankle | — |
| 2020 | 6 | Laremy Tunsil | T | Shoulder | — |
| 2020 | 6 | Jordan Akins | TE | Ankle / Concussion | Questionable |
| 2020 | 6 | Cornell Armstrong | CB | Knee | Questionable |
| 2020 | 6 | Buddy Howell | RB | Hamstring | Questionable |
| 2020 | 6 | Peter Kalambayi | LB | Hamstring | Questionable |
| 2020 | 7 | J.J. Watt | DE | Not Injury Related | — |
| 2020 | 7 | Dylan Cole | LB | Knee | — |
| 2020 | 7 | Keion Crossen | CB | Foot | — |
| 2020 | 7 | Buddy Howell | RB | Hamstring | — |
| 2020 | 7 | Senio Kelemete | G | Knee | — |
| 2020 | 7 | Justin Reid | S | Shoulder | — |
| 2020 | 7 | Laremy Tunsil | T | Shoulder | — |
| 2020 | 7 | P.J. Hall | DT | Illness | Questionable |
| 2020 | 7 | Jordan Akins | TE | Ankle / Concussion | Questionable |
| 2020 | 7 | Peter Kalambayi | LB | Hamstring | Questionable |
| 2020 | 9 | Jordan Akins | TE | Ankle / Concussion | — |
| 2020 | 9 | Randall Cobb | WR | Illness | — |
| 2020 | 9 | Peter Kalambayi | LB | Hamstring | — |
| 2020 | 9 | Kyle Emanuel | LB | Concussion | Out |
| 2020 | 9 | Bradley Roby | CB | Not Injury Related | Out |
| 2020 | 10 | Josh McCown | QB | Not Injury Related | Out |
| 2020 | 10 | David Johnson | RB | Concussion | Out |
| 2020 | 10 | Senio Kelemete | G | Concussion | Out |
| 2020 | 10 | Charles Omenihu | DE | Hamstring | Questionable |
| 2020 | 10 | Dylan Cole | LB | Back | Questionable |
| 2020 | 11 | Duke Johnson | RB | Illness | — |
| 2020 | 11 | Michael Thomas | S | Shoulder | Out |
| 2020 | 11 | Laremy Tunsil | T | Illness | Questionable |
| 2020 | 11 | Bryan Anger | P | right Quadricep | Questionable |
| 2020 | 11 | Cullen Gillaspia | RB | Back | Questionable |
| 2020 | 11 | Senio Kelemete | G | Concussion | Questionable |
| 2020 | 11 | Jacob Martin | LB | Not Injury Related | Questionable |
| 2020 | 11 | Charles Omenihu | DE | Hamstring | Questionable |
| 2020 | 11 | Kenny Stills | WR | Back | Questionable |
| 2020 | 12 | Randall Cobb | WR | Toe | — |
| 2020 | 12 | P.J. Hall | DT | Knee / Shoulder | — |
| 2020 | 12 | Senio Kelemete | G | Concussion | — |
| 2020 | 12 | Laremy Tunsil | T | Illness | — |
| 2020 | 12 | Cullen Gillaspia | RB | Back | Out |
| 2020 | 12 | Josh McCown | QB | Illness | Out |
| 2020 | 12 | Kenny Stills | WR | Quadricep | Out |
| 2020 | 12 | Bryan Anger | P | right Quadricep | Questionable |
| 2020 | 13 | Bryan Anger | P | right Quadricep | — |
| 2020 | 13 | Lonnie Johnson | CB | Knee | — |
| 2020 | 13 | Cullen Gillaspia | RB | Back | Out |
| 2020 | 13 | C.J. Prosise | RB | Illness | Out |
| 2020 | 13 | Ross Blacklock | DT | Illness | Questionable |
| 2020 | 14 | David Johnson | RB | Not Injury Related | — |
| 2020 | 14 | Duke Johnson | RB | Illness | — |
| 2020 | 14 | C.J. Prosise | RB | Illness | — |
| 2020 | 14 | Pharaoh Brown | TE | Concussion | Out |
| 2020 | 14 | AJ McCarron | QB | Not Injury Related | Questionable |
| 2020 | 14 | Keke Coutee | WR | Knee | Questionable |
| 2020 | 14 | Brandin Cooks | WR | Foot / Neck | Questionable |
| 2020 | 14 | Keion Crossen | CB | Foot | Questionable |
| 2020 | 14 | Phillip Gaines | CB | Knee / Shoulder | Questionable |
| 2020 | 14 | Jonathan Greenard | LB | Illness | Questionable |
| 2020 | 14 | John Reid | CB | Neck | Questionable |
| 2020 | 15 | Hjalte Froholdt | G | Not Injury Related | — |
| 2020 | 15 | Cornell Armstrong | CB | Hamstring | — |
| 2020 | 15 | Pharaoh Brown | TE | Concussion | — |
| 2020 | 15 | Brandin Cooks | WR | Neck | — |
| 2020 | 15 | David Johnson | RB | Not Injury Related | — |
| 2020 | 15 | Duke Johnson | RB | Neck | Questionable |
| 2020 | 15 | C.J. Prosise | RB | Ankle | Questionable |
| 2020 | 15 | Phillip Gaines | CB | Knee | Questionable |
| 2020 | 15 | Lonnie Johnson | S | Knee | Questionable |
| 2020 | 15 | John Reid | CB | Neck | Questionable |
| 2020 | 16 | Cornell Armstrong | CB | Hamstring | — |
| 2020 | 16 | Pharaoh Brown | TE | Ankle | — |
| 2020 | 16 | Keke Coutee | WR | Foot | — |
| 2020 | 16 | C.J. Prosise | RB | Ankle | — |
| 2020 | 16 | John Reid | CB | Neck | — |
| 2020 | 16 | Duke Johnson | RB | Neck | Out |
| 2020 | 16 | Phillip Gaines | CB | Knee | Questionable |
| 2020 | 17 | Keke Coutee | WR | Foot | — |
| 2020 | 17 | Brent Qvale | T | Concussion | Out |
| 2020 | 17 | Laremy Tunsil | T | Ankle | Doubtful |
| 2020 | 17 | Phillip Gaines | CB | Knee | Questionable |
| 2020 | 17 | Duke Johnson | RB | Neck | Questionable |
| 2021 | 1 | Maliek Collins | DT | Knee | — |
| 2021 | 1 | Whitney Mercilus | DE | Thigh | — |
| 2021 | 1 | Lonnie Johnson | CB | Thigh | Out |
| 2021 | 1 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 1 | Jonathan Greenard | DE | Illness | Questionable |
| 2021 | 1 | Kevin Pierre-Louis | LB | Thigh | Questionable |
| 2021 | 2 | Kevin Pierre-Louis | LB | Thigh | — |
| 2021 | 2 | Jonathan Greenard | DE | Illness | — |
| 2021 | 2 | Lonnie Johnson | CB | Thigh | — |
| 2021 | 2 | Desmond King | CB | Knee | — |
| 2021 | 2 | Andre Roberts | WR | Knee | — |
| 2021 | 2 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 2 | Kamu Grugier-Hill | LB | Illness | Questionable |
| 2021 | 2 | Pharaoh Brown | TE | Ankle / Shoulder | Questionable |
| 2021 | 3 | Nico Collins | WR | Shoulder | — |
| 2021 | 3 | Tyrod Taylor | QB | Thigh | — |
| 2021 | 3 | Danny Amendola | WR | Thigh | Out |
| 2021 | 3 | Terrance Mitchell | CB | Concussion | Out |
| 2021 | 3 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 3 | Kamu Grugier-Hill | LB | Knee | Questionable |
| 2021 | 3 | Justin Reid | S | Knee | Questionable |
| 2021 | 4 | Ross Blacklock | DT | Illness | — |
| 2021 | 4 | Justin Britt | C | Thigh | — |
| 2021 | 4 | Kamu Grugier-Hill | LB | Knee | — |
| 2021 | 4 | Justin Reid | S | Knee | — |
| 2021 | 4 | Jimmy Moreland | CB | Illness | Out |
| 2021 | 4 | Danny Amendola | WR | Thigh | Out |
| 2021 | 4 | Scottie Phillips | RB | Illness | Out |
| 2021 | 4 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 4 | Terrance Mitchell | CB | Concussion / Illness | Questionable |
| 2021 | 4 | Garret Wallow | LB | Illness | Questionable |
| 2021 | 5 | Chris Conley | WR | Not injury related - personal matter | — |
| 2021 | 5 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2021 | 5 | Justin Britt | C | Knee | — |
| 2021 | 5 | Jimmy Moreland | CB | Illness | — |
| 2021 | 5 | Scottie Phillips | RB | Illness | — |
| 2021 | 5 | Rex Burkhead | RB | Hip | Out |
| 2021 | 5 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 5 | Marcus Cannon | T | Back | Questionable |
| 2021 | 5 | Brevin Jordan | TE | Illness | Questionable |
| 2021 | 5 | Danny Amendola | WR | Thigh | Questionable |
| 2021 | 6 | Mark Ingram | RB | Not injury related - resting player | — |
| 2021 | 6 | Pharaoh Brown | TE | Shoulder | — |
| 2021 | 6 | Kamu Grugier-Hill | LB | Hip | — |
| 2021 | 6 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2021 | 6 | Laremy Tunsil | T | Thumb | Out |
| 2021 | 6 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 6 | Justin Britt | C | Knee | Questionable |
| 2021 | 6 | Desmond King | CB | Hip / Illness | Questionable |
| 2021 | 6 | Danny Amendola | WR | Thigh | Questionable |
| 2021 | 6 | Rex Burkhead | RB | Hip / Knee | Questionable |
| 2021 | 7 | Ross Blacklock | DT | Not injury related - personal matter | — |
| 2021 | 7 | Terrence Brooks | S | Chest | — |
| 2021 | 7 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2021 | 7 | Danny Amendola | WR | Thigh | — |
| 2021 | 7 | Jaleel Johnson | DT | Back | Out |
| 2021 | 7 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 7 | Justin Britt | C | Knee | Questionable |
| 2021 | 7 | Nico Collins | WR | Foot | Questionable |
| 2021 | 7 | Chris Conley | WR | Neck | Questionable |
| 2021 | 8 | Mark Ingram | RB | Not injury related - resting player | — |
| 2021 | 8 | Rex Burkhead | RB | Hip | — |
| 2021 | 8 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2021 | 8 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 8 | Pharaoh Brown | TE | Thigh | Questionable |
| 2021 | 8 | Justin Britt | C | Knee | Questionable |
| 2021 | 8 | Jaleel Johnson | DT | Back | Questionable |
| 2021 | 8 | Christian Kirksey | LB | Thumb | Questionable |
| 2021 | 8 | Justin McCray | C | Ankle | Questionable |
| 2021 | 9 | Danny Amendola | WR | Not injury related - resting player | — |
| 2021 | 9 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2021 | 9 | Rex Burkhead | RB | Hip | — |
| 2021 | 9 | Chris Conley | WR | Calf | — |
| 2021 | 9 | Jonathan Greenard | DE | Foot | — |
| 2021 | 9 | Brevin Jordan | TE | Ankle | — |
| 2021 | 9 | Jacob Martin | DE | Knee | — |
| 2021 | 9 | Justin McCray | C | Ankle | — |
| 2021 | 9 | Kevin Pierre-Louis | LB | Illness | — |
| 2021 | 9 | Pharaoh Brown | TE | Thigh | Out |
| 2021 | 9 | Christian Kirksey | LB | Thumb | Out |
| 2021 | 9 | Hardy Nickerson | LB | Concussion | Out |
| 2021 | 9 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 11 | Pharaoh Brown | TE | Thigh | — |
| 2021 | 11 | Danny Amendola | WR | Not injury related - resting player | — |
| 2021 | 11 | Rex Burkhead | RB | Not injury related - resting player | — |
| 2021 | 11 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2021 | 11 | Hardy Nickerson | LB | Concussion | Out |
| 2021 | 11 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 11 | Cre'von LeBlanc | CB | Illness | Questionable |
| 2021 | 11 | Jonathan Greenard | DE | Foot | Questionable |
| 2021 | 12 | Danny Amendola | WR | Not injury related - resting player | — |
| 2021 | 12 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2021 | 12 | Kamu Grugier-Hill | LB | Knee | — |
| 2021 | 12 | A.J. Moore | S | Back | — |
| 2021 | 12 | Rex Burkhead | RB | Not injury related - resting player | — |
| 2021 | 12 | Jordan Jenkins | DE | Knee | Out |
| 2021 | 12 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 12 | Davion Davis | WR | Illness | Questionable |
| 2021 | 12 | Nico Collins | WR | Hip | Questionable |
| 2021 | 12 | Jonathan Greenard | DE | Foot | Questionable |
| 2021 | 12 | Lonnie Johnson | CB | Illness / Foot | Questionable |
| 2021 | 13 | Jacob Martin | DE | Shin | — |
| 2021 | 13 | Terrance Mitchell | CB | Illness | — |
| 2021 | 13 | Danny Amendola | WR | Knee | Out |
| 2021 | 13 | Terrence Brooks | S | Hamstring | Out |
| 2021 | 13 | Justin McCray | C | Concussion | Out |
| 2021 | 13 | DeMarcus Walker | DE | Hamstring | Out |
| 2021 | 13 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 13 | David Johnson | RB | Illness / Thigh | Questionable |
| 2021 | 13 | Roy Lopez | DT | Illness | Questionable |
| 2021 | 13 | Chris Conley | WR | Illness | Questionable |
| 2021 | 13 | Brandin Cooks | WR | Illness | Questionable |
| 2021 | 13 | Jonathan Greenard | DE | Foot | Questionable |
| 2021 | 13 | Cole Toner | C | Illness | Questionable |
| 2021 | 14 | Justin Britt | C | Knee | — |
| 2021 | 14 | Nico Collins | WR | Thigh | — |
| 2021 | 14 | Maliek Collins | DT | Illness | — |
| 2021 | 14 | Tytus Howard | T | Ankle | — |
| 2021 | 14 | David Johnson | RB | Illness / Thigh | — |
| 2021 | 14 | Christian Kirksey | LB | Thumb | — |
| 2021 | 14 | Jacob Martin | DE | Knee | — |
| 2021 | 14 | Justin McCray | C | Concussion | — |
| 2021 | 14 | Terrance Mitchell | CB | Illness | — |
| 2021 | 14 | Tyrod Taylor | QB | left Wrist | — |
| 2021 | 14 | Rex Burkhead | RB | Not injury related - resting player | — |
| 2021 | 14 | Terrence Brooks | S | Hamstring | Out |
| 2021 | 14 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 14 | Kevin Pierre-Louis | LB | Hamstring / Wrist | Questionable |
| 2021 | 14 | Brandin Cooks | WR | Back | Questionable |
| 2021 | 14 | Jonathan Greenard | DE | Foot | Questionable |
| 2021 | 14 | Brevin Jordan | TE | Hand | Questionable |
| 2021 | 14 | A.J. Moore | S | Hip | Questionable |
| 2021 | 14 | Jimmy Moreland | CB | Foot | Questionable |
| 2021 | 15 | Terrence Brooks | S | Hamstring | — |
| 2021 | 15 | Terrance Mitchell | CB | Ankle / Knee | — |
| 2021 | 15 | Justin Britt | C | Knee | — |
| 2021 | 15 | Pharaoh Brown | TE | Illness | — |
| 2021 | 15 | Tyrod Taylor | QB | left Wrist | — |
| 2021 | 15 | Jimmy Moreland | CB | Illness | Out |
| 2021 | 15 | Justin Reid | S | Concussion / Illness | Out |
| 2021 | 15 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 15 | Brevin Jordan | TE | Hand | Questionable |
| 2021 | 15 | Rex Burkhead | RB | Hip / Quadricep | Questionable |
| 2021 | 15 | Kevin Pierre-Louis | LB | Hamstring / Wrist | Questionable |
| 2021 | 16 | Chris Conley | WR | Knee | — |
| 2021 | 16 | Jordan Jenkins | DE | Knee | — |
| 2021 | 16 | Brevin Jordan | TE | Hand | — |
| 2021 | 16 | Justin Reid | S | Concussion | — |
| 2021 | 16 | Justin Britt | C | Knee | — |
| 2021 | 16 | Lonnie Johnson | CB | Quadricep / Shoulder | — |
| 2021 | 16 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 16 | David Johnson | RB | Quadricep | Questionable |
| 2021 | 17 | Antony Auclair | TE | Illness | — |
| 2021 | 17 | Justin Britt | C | Knee | — |
| 2021 | 17 | Jonathan Greenard | DE | Foot | — |
| 2021 | 17 | Kamu Grugier-Hill | LB | Knee | — |
| 2021 | 17 | Jordan Jenkins | DE | Knee | — |
| 2021 | 17 | DeMarcus Walker | DE | Hamstring | — |
| 2021 | 17 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 17 | Chris Conley | WR | Knee | Questionable |
| 2021 | 17 | A.J. Moore | S | Illness | Questionable |
| 2021 | 17 | Jimmy Moreland | CB | Illness | Questionable |
| 2021 | 18 | Justin Britt | C | Knee | — |
| 2021 | 18 | Jonathan Greenard | DE | Shoulder | — |
| 2021 | 18 | Kamu Grugier-Hill | LB | Knee | — |
| 2021 | 18 | Deshaun Watson | QB | Not injury related - personal matter | Out |
| 2021 | 18 | Chris Conley | WR | Knee | Questionable |
| 2021 | 18 | Jordan Akins | TE | Illness | Questionable |
| 2021 | 18 | Chris Moore | WR | Illness | Questionable |
| 2022 | 1 | Mario Addison | DE | Thigh | Doubtful |
| 2022 | 1 | Rasheem Green | DE | Thigh | Questionable |
| 2022 | 2 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 2 | Maliek Collins | DT | Knee | — |
| 2022 | 2 | Rasheem Green | DE | Thigh | — |
| 2022 | 2 | Isaac Yiadom | CB | Abdomen | — |
| 2022 | 2 | Justin Britt | C | Not injury related - personal matter | Out |
| 2022 | 2 | Brevin Jordan | TE | Ankle | Questionable |
| 2022 | 3 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 3 | Steven Nelson | CB | Not injury related - personal matter | — |
| 2022 | 3 | Blake Cashman | LB | Hip | — |
| 2022 | 3 | Kamu Grugier-Hill | LB | Neck | — |
| 2022 | 3 | Davis Mills | QB | right Thumb | — |
| 2022 | 3 | Austin Deculus | T | Ankle | Out |
| 2022 | 3 | Brevin Jordan | TE | Ankle | Out |
| 2022 | 3 | Isaac Yiadom | CB | Thigh | Out |
| 2022 | 3 | Maliek Collins | DT | Knee | Questionable |
| 2022 | 3 | Kurt Hinish | DT | Foot | Questionable |
| 2022 | 3 | Pharaoh Brown | TE | Shoulder | Questionable |
| 2022 | 4 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2022 | 4 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 4 | Blake Cashman | LB | Hip | — |
| 2022 | 4 | Maliek Collins | DT | Knee | — |
| 2022 | 4 | Dameon Pierce | RB | Hip | — |
| 2022 | 4 | M.J. Stewart | S | Hip | — |
| 2022 | 4 | Austin Deculus | T | Ankle | Out |
| 2022 | 4 | Brevin Jordan | TE | Ankle | Out |
| 2022 | 4 | Kurt Hinish | DT | Foot | Questionable |
| 2022 | 4 | Jalen Reeves-Maybin | LB | Back | Questionable |
| 2022 | 4 | Isaac Yiadom | CB | Thigh | Questionable |
| 2022 | 4 | Pharaoh Brown | TE | Shoulder / Hip | Questionable |
| 2022 | 5 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 5 | Christian Kirksey | LB | Not injury related - resting player | — |
| 2022 | 5 | Maliek Collins | DT | Knee | — |
| 2022 | 5 | Kenyon Green | G | Knee | — |
| 2022 | 5 | Kurt Hinish | DT | Illness | — |
| 2022 | 5 | Tytus Howard | T | Ankle | — |
| 2022 | 5 | Derek Stingley | CB | Elbow / Shoulder | — |
| 2022 | 5 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2022 | 5 | Blake Cashman | LB | Concussion | Out |
| 2022 | 5 | Austin Deculus | T | Ankle | Out |
| 2022 | 5 | Brevin Jordan | TE | Ankle | Out |
| 2022 | 5 | Chris Moore | WR | Hip | Out |
| 2022 | 5 | Jonathan Greenard | DE | Ankle | Questionable |
| 2022 | 5 | Jake Hansen | LB | Ankle | Questionable |
| 2022 | 7 | Brandin Cooks | WR | Not injury related - resting player | — |
| 2022 | 7 | Nico Collins | WR | Achilles / Wrist | — |
| 2022 | 7 | Maliek Collins | DT | Knee | — |
| 2022 | 7 | Jerry Hughes | DE | Knee | — |
| 2022 | 7 | Jonathan Greenard | DE | Calf | Out |
| 2022 | 7 | Austin Deculus | T | Ankle | Questionable |
| 2022 | 7 | Brevin Jordan | TE | Ankle | Questionable |
| 2022 | 7 | Chris Moore | WR | Hip | Questionable |
| 2022 | 8 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 8 | A.J. Cann | G | Illness | Questionable |
| 2022 | 8 | Maliek Collins | DT | Chest | Questionable |
| 2022 | 8 | Nico Collins | WR | Groin | Questionable |
| 2022 | 8 | Brandin Cooks | WR | Wrist | Questionable |
| 2022 | 8 | Kenyon Green | G | Shoulder | Questionable |
| 2022 | 8 | Justin McCray | C | Hand | Questionable |
| 2022 | 8 | Rasheem Green | DE | Knee | Questionable |
| 2022 | 9 | A.J. Cann | G | Illness | — |
| 2022 | 9 | Roy Lopez | DT | Shoulder | — |
| 2022 | 9 | Grayland Arnold | S | Quadricep | Out |
| 2022 | 9 | Nico Collins | WR | Groin | Out |
| 2022 | 9 | Maliek Collins | DT | Chest | Out |
| 2022 | 9 | Neville Hewitt | LB | Hamstring | Out |
| 2022 | 9 | Justin McCray | C | Concussion | Out |
| 2022 | 9 | Brandin Cooks | WR | Wrist / Not injury related - personal matter | Questionable |
| 2022 | 9 | Christian Harris | LB | Thigh | Questionable |
| 2022 | 9 | Desmond King | CB | Knee | Questionable |
| 2022 | 10 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 10 | Phillip Dorsett | WR | Ankle | — |
| 2022 | 10 | Jaleel Johnson | DT | Illness | — |
| 2022 | 10 | Justin McCray | C | Concussion | — |
| 2022 | 10 | Dameon Pierce | RB | Chest / Shoulder | — |
| 2022 | 10 | Neville Hewitt | LB | Hamstring | Out |
| 2022 | 10 | Jalen Reeves-Maybin | LB | Groin | Questionable |
| 2022 | 10 | Maliek Collins | DT | Chest | Questionable |
| 2022 | 10 | Nico Collins | WR | Groin | Questionable |
| 2022 | 10 | Brandin Cooks | WR | Wrist | Questionable |
| 2022 | 11 | Mario Addison | DE | Not injury related - resting player | — |
| 2022 | 11 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 11 | Maliek Collins | DT | Chest | — |
| 2022 | 11 | Nico Collins | WR | Groin | — |
| 2022 | 11 | Brandin Cooks | WR | Hip / Wrist | — |
| 2022 | 11 | Kenyon Green | G | Shoulder | — |
| 2022 | 11 | Christian Kirksey | LB | Neck | — |
| 2022 | 11 | Dare Ogunbowale | RB | Foot | — |
| 2022 | 11 | Jalen Reeves-Maybin | LB | Groin | — |
| 2022 | 11 | Derek Stingley | CB | Hamstring | Out |
| 2022 | 11 | Neville Hewitt | LB | Hamstring | Out |
| 2022 | 11 | Rasheem Green | DE | Illness | Questionable |
| 2022 | 12 | Jonathan Weeks | LS | Not injury related - personal matter | — |
| 2022 | 12 | Maliek Collins | DT | Chest | — |
| 2022 | 12 | Neville Hewitt | LB | Hamstring | — |
| 2022 | 12 | Derek Stingley | CB | Hamstring | Out |
| 2022 | 13 | Mario Addison | DE | Not injury related - resting player | — |
| 2022 | 13 | Austin Deculus | T | Not injury related - personal matter | — |
| 2022 | 13 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 13 | Blake Cashman | LB | Knee | — |
| 2022 | 13 | Maliek Collins | DT | Chest | — |
| 2022 | 13 | Kenyon Green | G | Illness | — |
| 2022 | 13 | Christian Harris | LB | Shoulder | — |
| 2022 | 13 | Brandin Cooks | WR | Calf | Out |
| 2022 | 13 | Derek Stingley | CB | Hamstring | Out |
| 2022 | 13 | Rex Burkhead | RB | Concussion | Questionable |
| 2022 | 14 | Maliek Collins | DT | Not injury related - resting player | — |
| 2022 | 14 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 14 | Mario Addison | DE | Knee | — |
| 2022 | 14 | Ka'imi Fairbairn | K | right Groin | — |
| 2022 | 14 | Garret Wallow | LB | Ankle | — |
| 2022 | 14 | Nico Collins | WR | Foot | Out |
| 2022 | 14 | Brandin Cooks | WR | Calf | Out |
| 2022 | 14 | Kurt Hinish | DT | Shoulder | Out |
| 2022 | 14 | Derek Stingley | CB | Hamstring / Illness | Out |
| 2022 | 14 | Justin McCray | C | Hamstring | Questionable |
| 2022 | 14 | Troy Hairston | FB | Chest | Questionable |
| 2022 | 15 | Mario Addison | DE | Not injury related - resting player | — |
| 2022 | 15 | Maliek Collins | DT | Not injury related - resting player | — |
| 2022 | 15 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 15 | Troy Hairston | FB | Chest | — |
| 2022 | 15 | Kurt Hinish | DT | Shoulder | — |
| 2022 | 15 | Roy Lopez | DT | Hip | — |
| 2022 | 15 | Laremy Tunsil | T | Illness | — |
| 2022 | 15 | Nico Collins | WR | Foot | Out |
| 2022 | 15 | Steven Nelson | CB | Foot | Out |
| 2022 | 15 | Dameon Pierce | RB | Ankle | Out |
| 2022 | 15 | Taylor Stallworth | DT | Calf | Out |
| 2022 | 15 | Derek Stingley | CB | Hamstring | Out |
| 2022 | 15 | Brandin Cooks | WR | Calf | Out |
| 2022 | 15 | Kenyon Green | G | Ankle | Out |
| 2022 | 15 | Justin McCray | C | Hamstring | Questionable |
| 2022 | 16 | Mario Addison | DE | Not injury related - resting player | — |
| 2022 | 16 | Maliek Collins | DT | Not injury related - resting player | — |
| 2022 | 16 | Jerry Hughes | DE | Not injury related - resting player | — |
| 2022 | 16 | Christian Kirksey | LB | Elbow | — |
| 2022 | 16 | Ogbonnia Okoronkwo | DE | Illness | — |
| 2022 | 16 | Laremy Tunsil | T | Illness | — |
| 2022 | 16 | Nico Collins | WR | Foot | Out |
| 2022 | 16 | Kenyon Green | G | Ankle | Out |
| 2022 | 16 | Brandin Cooks | WR | Calf | Questionable |
| 2022 | 16 | Steven Nelson | CB | Foot / Knee | Questionable |
| 2022 | 16 | Justin McCray | C | Hamstring | Questionable |
| 2022 | 16 | Chris Moore | WR | Foot | Questionable |
| 2022 | 17 | Brandin Cooks | WR | Not injury related - personal matter | — |
| 2022 | 17 | Kenyon Green | G | Ankle | — |
| 2022 | 17 | Tytus Howard | T | Concussion | — |
| 2022 | 17 | Justin McCray | C | Hamstring | — |
| 2022 | 17 | M.J. Stewart | S | Concussion | — |
| 2022 | 17 | Jimmy Morrissey | C | Concussion | Out |
| 2022 | 17 | Teagan Quitoriano | TE | Thigh | Out |
| 2022 | 17 | Dare Ogunbowale | RB | Knee | Questionable |
| 2022 | 18 | Teagan Quitoriano | TE | Thigh | — |
| 2022 | 18 | Phillip Dorsett | WR | Hamstring | Out |
| 2022 | 18 | Jimmy Morrissey | C | Concussion | Out |
| 2022 | 18 | Steven Nelson | CB | Illness | Questionable |
| 2022 | 18 | O.J. Howard | TE | Hip | Questionable |
| 2022 | 18 | Ogbonnia Okoronkwo | DE | Illness | Questionable |
| 2023 | 1 | Christian Harris | LB | Shoulder | — |
| 2023 | 1 | Blake Cashman | LB | Hamstring | Out |
| 2023 | 1 | John Metchie | WR | Hamstring | Out |
| 2023 | 1 | Jimmie Ward | S | Hip | Out |
| 2023 | 1 | Dare Ogunbowale | RB | Hamstring | Questionable |
| 2023 | 2 | Grayland Arnold | S | Hamstring | — |
| 2023 | 2 | Blake Cashman | LB | Hamstring | — |
| 2023 | 2 | George Fant | T | Shoulder | — |
| 2023 | 2 | John Metchie | WR | Hamstring | — |
| 2023 | 2 | Dare Ogunbowale | RB | Hamstring | — |
| 2023 | 2 | Denzel Perryman | LB | Ankle / Wrist | — |
| 2023 | 2 | Dalton Schultz | TE | Thigh | — |
| 2023 | 2 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 2 | Jalen Pitre | S | Chest | Out |
| 2023 | 2 | Jimmie Ward | S | Hip | Out |
| 2023 | 2 | Laremy Tunsil | T | Knee | Questionable |
| 2023 | 2 | Neville Hewitt | LB | Illness | Questionable |
| 2023 | 2 | C.J. Stroud | QB | right Shoulder | Questionable |
| 2023 | 3 | Tank Dell | WR | Thigh | — |
| 2023 | 3 | George Fant | T | Ankle / Knee | — |
| 2023 | 3 | Jonathan Greenard | DE | Knee | — |
| 2023 | 3 | Eric Murray | S | Concussion | — |
| 2023 | 3 | C.J. Stroud | QB | right Shoulder | — |
| 2023 | 3 | Jimmie Ward | S | Hip | — |
| 2023 | 3 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 3 | Denzel Perryman | LB | Hand / Wrist | Out |
| 2023 | 3 | Jalen Pitre | S | Chest | Out |
| 2023 | 3 | Derek Stingley | CB | Hamstring | Out |
| 2023 | 3 | Tavierre Thomas | CB | Hand | Out |
| 2023 | 3 | Laremy Tunsil | T | Knee | Questionable |
| 2023 | 4 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 4 | Jonathan Greenard | DE | Knee | — |
| 2023 | 4 | Shaquill Griffin | CB | Foot | — |
| 2023 | 4 | Shaquille Mason | G | Ankle | — |
| 2023 | 4 | Jalen Pitre | S | Chest | — |
| 2023 | 4 | Tank Dell | WR | Not injury related - resting player | — |
| 2023 | 4 | George Fant | T | Not injury related - resting player | — |
| 2023 | 4 | Jimmie Ward | S | Not injury related - resting player | — |
| 2023 | 4 | Josh Jones | G | Hand | Out |
| 2023 | 4 | Denzel Perryman | LB | Hand / Wrist | Out |
| 2023 | 4 | Tavierre Thomas | CB | Hand | Out |
| 2023 | 4 | Laremy Tunsil | T | Knee | Out |
| 2023 | 4 | Michael Deiter | C | Chest | Questionable |
| 2023 | 5 | Jimmie Ward | S | Not injury related - resting player | — |
| 2023 | 5 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 5 | Michael Deiter | C | Chest | — |
| 2023 | 5 | Tytus Howard | T | Hand | — |
| 2023 | 5 | Cameron Johnston | P | Calf | — |
| 2023 | 5 | Shaquille Mason | G | Ankle | — |
| 2023 | 5 | Denzel Perryman | LB | Hand | — |
| 2023 | 5 | Dameon Pierce | RB | Knee | — |
| 2023 | 5 | Tavierre Thomas | CB | Hand | — |
| 2023 | 5 | Steven Nelson | CB | Not injury related - resting player | — |
| 2023 | 5 | Christian Harris | LB | Concussion | Out |
| 2023 | 5 | Josh Jones | G | Hand | Out |
| 2023 | 5 | John Metchie | WR | Illness | Questionable |
| 2023 | 5 | Laremy Tunsil | T | Knee | Questionable |
| 2023 | 5 | Maliek Collins | DT | Abdomen | Questionable |
| 2023 | 5 | Shaquill Griffin | CB | Calf | Questionable |
| 2023 | 5 | Jake Hansen | LB | Neck | Questionable |
| 2023 | 6 | Noah Brown | WR | Groin | — |
| 2023 | 6 | Blake Cashman | LB | Wrist | — |
| 2023 | 6 | Maliek Collins | DT | Abdomen | — |
| 2023 | 6 | George Fant | T | Hip / Shoulder | — |
| 2023 | 6 | Shaquill Griffin | CB | Calf | — |
| 2023 | 6 | Tytus Howard | T | Hand | — |
| 2023 | 6 | Josh Jones | G | Hand | — |
| 2023 | 6 | Shaquille Mason | G | Ankle | — |
| 2023 | 6 | Denzel Perryman | LB | Hand / Wrist | — |
| 2023 | 6 | Tavierre Thomas | CB | Hand | — |
| 2023 | 6 | Laremy Tunsil | T | Knee | — |
| 2023 | 6 | Christian Harris | LB | Concussion | Questionable |
| 2023 | 6 | Robert Woods | WR | Ribs | Questionable |
| 2023 | 6 | Tank Dell | WR | Concussion | Questionable |
| 2023 | 8 | Blake Cashman | LB | Wrist | — |
| 2023 | 8 | Tank Dell | WR | Concussion | — |
| 2023 | 8 | Josh Jones | G | Hand | — |
| 2023 | 8 | Denzel Perryman | LB | Hand | — |
| 2023 | 8 | Tavierre Thomas | CB | Hand | — |
| 2023 | 8 | Laremy Tunsil | T | Knee | — |
| 2023 | 8 | Jimmie Ward | S | Not injury related - resting player | — |
| 2023 | 8 | Brevin Jordan | TE | Foot | Out |
| 2023 | 8 | Sheldon Rankins | DT | Knee | Out |
| 2023 | 8 | Robert Woods | WR | Foot | Out |
| 2023 | 8 | Tytus Howard | T | Hand / Knee | Questionable |
| 2023 | 8 | Xavier Hutchinson | WR | Foot | Questionable |
| 2023 | 8 | Hassan Ridgeway | DT | Calf | Questionable |
| 2023 | 9 | Blake Cashman | LB | Wrist | — |
| 2023 | 9 | George Fant | T | Foot / Shoulder | — |
| 2023 | 9 | Ka'dar Hollman | CB | Ankle | — |
| 2023 | 9 | Tytus Howard | T | Knee | — |
| 2023 | 9 | Josh Jones | G | Hand | — |
| 2023 | 9 | Denzel Perryman | LB | Hand / Wrist | — |
| 2023 | 9 | Tavierre Thomas | CB | Hand | — |
| 2023 | 9 | Laremy Tunsil | T | Knee | — |
| 2023 | 9 | Jimmie Ward | S | Not injury related - resting player | — |
| 2023 | 9 | Brevin Jordan | TE | Knee | Out |
| 2023 | 9 | Dameon Pierce | RB | Ankle | Out |
| 2023 | 9 | Robert Woods | WR | Foot | Out |
| 2023 | 9 | Sheldon Rankins | DT | Knee | Questionable |
| 2023 | 10 | Will Anderson | DE | Knee | — |
| 2023 | 10 | Blake Cashman | LB | Knee | — |
| 2023 | 10 | George Fant | T | Knee | — |
| 2023 | 10 | Jonathan Greenard | DE | Shoulder | — |
| 2023 | 10 | Christian Harris | LB | Hand | — |
| 2023 | 10 | Charlie Heck | T | Back | — |
| 2023 | 10 | Tytus Howard | T | Knee | — |
| 2023 | 10 | Josh Jones | G | Hand | — |
| 2023 | 10 | John Metchie | WR | Ribs | — |
| 2023 | 10 | Sheldon Rankins | DT | Knee | — |
| 2023 | 10 | Myjai Sanders | LB | Knee | — |
| 2023 | 10 | Derek Stingley | CB | Hamstring | — |
| 2023 | 10 | Laremy Tunsil | T | Knee | — |
| 2023 | 10 | Andrew Beck | FB | Ankle / Elbow | Out |
| 2023 | 10 | Nico Collins | WR | Calf | Out |
| 2023 | 10 | Ka'imi Fairbairn | K | Quadricep | Out |
| 2023 | 10 | Jake Hansen | LB | Hamstring / Hand | Out |
| 2023 | 10 | Brevin Jordan | TE | Foot | Out |
| 2023 | 10 | Dameon Pierce | RB | Ankle | Out |
| 2023 | 10 | Henry To'oTo'o | LB | Concussion | Out |
| 2023 | 10 | Jimmie Ward | S | Hamstring | Out |
| 2023 | 10 | Steven Nelson | CB | Back / Neck | Questionable |
| 2023 | 10 | Jerry Hughes | DE | Back | Questionable |
| 2023 | 10 | Robert Woods | WR | Foot | Questionable |
| 2023 | 11 | Andrew Beck | FB | Ankle / Elbow | — |
| 2023 | 11 | Nico Collins | WR | Calf | — |
| 2023 | 11 | George Fant | T | Hip | — |
| 2023 | 11 | Jonathan Greenard | DE | Shoulder | — |
| 2023 | 11 | Charlie Heck | T | Back | — |
| 2023 | 11 | Kurt Hinish | DT | Knee | — |
| 2023 | 11 | Tytus Howard | T | Knee | — |
| 2023 | 11 | Jerry Hughes | DE | Back | — |
| 2023 | 11 | Brevin Jordan | TE | Foot | — |
| 2023 | 11 | Steven Nelson | CB | Back / Neck | — |
| 2023 | 11 | Dalton Schultz | TE | Hamstring | — |
| 2023 | 11 | Laremy Tunsil | T | Knee | — |
| 2023 | 11 | Robert Woods | WR | Foot | — |
| 2023 | 11 | Grayland Arnold | S | Calf | Out |
| 2023 | 11 | Jake Hansen | LB | Hamstring / Hand | Out |
| 2023 | 11 | Henry To'oTo'o | LB | Concussion | Out |
| 2023 | 11 | Jimmie Ward | S | Hamstring | Out |
| 2023 | 11 | Dameon Pierce | RB | Ankle | Out |
| 2023 | 11 | Will Anderson | DE | Knee | Questionable |
| 2023 | 11 | Noah Brown | WR | Knee | Questionable |
| 2023 | 11 | Dylan Horton | DE | Knee | Questionable |
| 2023 | 12 | Dylan Horton | DE | Illness | — |
| 2023 | 12 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 12 | Will Anderson | DE | Knee | — |
| 2023 | 12 | Charlie Heck | T | Back | — |
| 2023 | 12 | Henry To'oTo'o | LB | Concussion | — |
| 2023 | 12 | Laremy Tunsil | T | Knee | — |
| 2023 | 12 | Noah Brown | WR | Knee | Out |
| 2023 | 12 | Jake Hansen | LB | Hamstring / Hand | Out |
| 2023 | 12 | Jimmie Ward | S | Hamstring | Out |
| 2023 | 12 | Case Keenum | QB | Calf | Questionable |
| 2023 | 12 | Dameon Pierce | RB | Ankle | Questionable |
| 2023 | 12 | Juice Scruggs | C | Hamstring | Questionable |
| 2023 | 13 | Maliek Collins | DT | Not injury related - personal matter | — |
| 2023 | 13 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 13 | George Fant | T | Hip | — |
| 2023 | 13 | C.J. Stroud | QB | Thigh | — |
| 2023 | 13 | Laremy Tunsil | T | Knee | — |
| 2023 | 13 | Jimmie Ward | S | Hamstring | — |
| 2023 | 13 | Dalton Schultz | TE | Hamstring | Out |
| 2023 | 13 | Noah Brown | WR | Knee | Questionable |
| 2023 | 13 | Jake Hansen | LB | Hamstring / Hand | Questionable |
| 2023 | 13 | Tank Dell | WR | Calf | Questionable |
| 2023 | 13 | Sheldon Rankins | DT | Elbow | Questionable |
| 2023 | 14 | Will Anderson | DE | Shoulder | — |
| 2023 | 14 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 14 | Neville Hewitt | LB | Hamstring | — |
| 2023 | 14 | Denzel Perryman | LB | Knee | — |
| 2023 | 14 | Laremy Tunsil | T | Knee | — |
| 2023 | 14 | Jimmie Ward | S | Shoulder | — |
| 2023 | 14 | DeAndre Houston-Carson | S | Illness | Out |
| 2023 | 14 | Dalton Schultz | TE | Hamstring | Out |
| 2023 | 14 | Noah Brown | WR | Knee | Questionable |
| 2023 | 14 | George Fant | T | Hip | Questionable |
| 2023 | 14 | Sheldon Rankins | DT | Elbow / Shoulder | Questionable |
| 2023 | 15 | Maliek Collins | DT | Chest | — |
| 2023 | 15 | Ka'imi Fairbairn | K | right Quadricep | — |
| 2023 | 15 | Dalton Schultz | TE | Hamstring | — |
| 2023 | 15 | Laremy Tunsil | T | Knee | — |
| 2023 | 15 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 15 | Will Anderson | DE | Ankle | Out |
| 2023 | 15 | Blake Cashman | LB | Hamstring | Out |
| 2023 | 15 | Tavierre Thomas | CB | Hamstring | Out |
| 2023 | 15 | C.J. Stroud | QB | Concussion | Doubtful |
| 2023 | 15 | Steven Nelson | CB | Wrist | Questionable |
| 2023 | 15 | Nico Collins | WR | Calf | Questionable |
| 2023 | 15 | George Fant | T | Hip | Questionable |
| 2023 | 15 | Noah Brown | WR | Knee | Questionable |
| 2023 | 15 | Shaquille Mason | G | Calf | Questionable |
| 2023 | 15 | Henry To'oTo'o | LB | Hamstring | Questionable |
| 2023 | 16 | Noah Brown | WR | Knee | — |
| 2023 | 16 | George Fant | T | Hip | — |
| 2023 | 16 | Brevin Jordan | TE | Illness | — |
| 2023 | 16 | Shaquille Mason | G | Calf | — |
| 2023 | 16 | John Metchie | WR | Illness | — |
| 2023 | 16 | Steven Nelson | CB | Hand | — |
| 2023 | 16 | Laremy Tunsil | T | Knee | — |
| 2023 | 16 | Jimmie Ward | S | Concussion | — |
| 2023 | 16 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 16 | Will Anderson | DE | Ankle | Out |
| 2023 | 16 | Blake Cashman | LB | Hamstring | Out |
| 2023 | 16 | C.J. Stroud | QB | Concussion | Out |
| 2023 | 16 | Nico Collins | WR | Calf | Questionable |
| 2023 | 16 | Maliek Collins | DT | Hip | Questionable |
| 2023 | 16 | Denzel Perryman | LB | Achilles | Questionable |
| 2023 | 17 | Adrian Amos | S | Not injury related - personal matter | — |
| 2023 | 17 | Noah Brown | WR | Knee | — |
| 2023 | 17 | Blake Cashman | LB | Hamstring | — |
| 2023 | 17 | Nico Collins | WR | Calf | — |
| 2023 | 17 | Shaquille Mason | G | Calf | — |
| 2023 | 17 | Denzel Perryman | DT | Ankle | — |
| 2023 | 17 | C.J. Stroud | QB | Concussion | — |
| 2023 | 17 | Laremy Tunsil | T | Knee | — |
| 2023 | 17 | Robert Woods | WR | Not injury related - resting player | — |
| 2023 | 17 | Jonathan Greenard | DE | Ankle | Out |
| 2023 | 17 | Maliek Collins | DT | Hip | Questionable |
| 2023 | 17 | Steven Nelson | CB | Foot / Hamstring | Questionable |
| 2023 | 17 | Will Anderson | DE | Ankle | Questionable |
| 2023 | 17 | Andrew Beck | FB | Calf | Questionable |
| 2023 | 17 | Sheldon Rankins | DT | Ankle | Questionable |
| 2023 | 18 | Noah Brown | WR | Back | Out |
| 2023 | 18 | Jonathan Greenard | DE | Ankle | Out |
| 2023 | 18 | Robert Woods | WR | Hip | Questionable |
| 2023 | 18 | Will Anderson | DE | Ankle | Questionable |
| 2023 | 18 | Andrew Beck | FB | Calf | Questionable |
| 2023 | 18 | Maliek Collins | DT | Hip | Questionable |
| 2023 | 18 | Sheldon Rankins | DT | Ankle | Questionable |
| 2023 | 18 | Laremy Tunsil | T | Groin | Questionable |
| 2023 | 19 (WC) | Shaquille Mason | G | Not injury related - resting player | — |
| 2023 | 19 (WC) | Laremy Tunsil | T | Not injury related - resting player | — |
| 2023 | 19 (WC) | Michael Deiter | C | Elbow | — |
| 2023 | 19 (WC) | Jerry Hughes | DE | Ankle | Out |
| 2023 | 19 (WC) | Will Anderson | DE | Ankle | Questionable |
| 2023 | 19 (WC) | Andrew Beck | FB | Calf | Questionable |
| 2023 | 19 (WC) | Noah Brown | WR | Back | Questionable |
| 2023 | 19 (WC) | Maliek Collins | DT | Hip | Questionable |
| 2023 | 19 (WC) | Jonathan Greenard | DE | Ankle | Questionable |
| 2023 | 19 (WC) | Sheldon Rankins | DT | Shoulder | Questionable |
| 2023 | 19 (WC) | Robert Woods | WR | Hip | Questionable |
| 2024 | 1 | M.J. Stewart | S | Knee | Out |
| 2024 | 2 | Nico Collins | WR | Illness | — |
| 2024 | 2 | Dalton Schultz | TE | Ankle | — |
| 2024 | 2 | M.J. Stewart | S | Knee | Out |
| 2024 | 2 | Dameon Pierce | RB | Hamstring | Questionable |
| 2024 | 2 | Juice Scruggs | C | Groin | Questionable |
| 2024 | 3 | Azeez Al-Shaair | LB | Shin | — |
| 2024 | 3 | Kris Boyd | CB | Hip | — |
| 2024 | 3 | Nico Collins | WR | Hip / Foot | — |
| 2024 | 3 | Folorunso Fatukasi | DT | Shoulder | — |
| 2024 | 3 | Kamari Lassiter | CB | Elbow | — |
| 2024 | 3 | Dalton Schultz | TE | Ankle | — |
| 2024 | 3 | Dameon Pierce | RB | Hamstring | Out |
| 2024 | 3 | Joe Mixon | RB | Ankle | Doubtful |
| 2024 | 3 | Jarrett Patterson | C | Calf | Questionable |
| 2024 | 3 | Juice Scruggs | C | Groin | Questionable |
| 2024 | 3 | M.J. Stewart | S | Knee | Questionable |
| 2024 | 4 | Nico Collins | WR | Hamstring | — |
| 2024 | 4 | Kenyon Green | G | Illness | — |
| 2024 | 4 | Jarrett Patterson | C | Calf | — |
| 2024 | 4 | Dalton Schultz | TE | Ankle | — |
| 2024 | 4 | Tank Dell | WR | Chest | Out |
| 2024 | 4 | Dameon Pierce | RB | Hamstring | Out |
| 2024 | 4 | Jimmie Ward | S | Groin | Out |
| 2024 | 4 | Folorunso Fatukasi | DT | Shoulder | Questionable |
| 2024 | 4 | Joe Mixon | RB | Ankle | Questionable |
| 2024 | 5 | Tank Dell | WR | Chest | — |
| 2024 | 5 | Blake Fisher | T | Illness | — |
| 2024 | 5 | Juice Scruggs | C | Hip | — |
| 2024 | 5 | Laremy Tunsil | T | Ankle | — |
| 2024 | 5 | Jimmie Ward | S | Groin | — |
| 2024 | 5 | Derek Barnett | DE | Shoulder | Out |
| 2024 | 5 | Jerry Hughes | DE | Hip | Out |
| 2024 | 5 | Joe Mixon | RB | Ankle | Out |
| 2024 | 5 | Azeez Al-Shaair | LB | Illness | Questionable |
| 2024 | 5 | Jake Hansen | LB | Back | Questionable |
| 2024 | 5 | Tytus Howard | T | Hamstring | Questionable |
| 2024 | 5 | Kurt Hinish | DT | Calf | Questionable |
| 2024 | 5 | Dylan Horton | DE | Illness | Questionable |
| 2024 | 5 | Dameon Pierce | RB | Hamstring | Questionable |
| 2024 | 5 | Robert Woods | WR | Foot | Questionable |
| 2024 | 6 | Kenyon Green | G | Knee | — |
| 2024 | 6 | Jake Hansen | LB | Back | — |
| 2024 | 6 | Tytus Howard | T | Hamstring | — |
| 2024 | 6 | Del'Shawn Phillips | LB | Hip | — |
| 2024 | 6 | Dameon Pierce | RB | Hamstring | — |
| 2024 | 6 | Laremy Tunsil | T | Ankle | — |
| 2024 | 6 | Stefon Diggs | WR | Not injury related - resting player | — |
| 2024 | 6 | Mario Edwards | DT | Not injury related - personal matter | — |
| 2024 | 6 | Kamari Lassiter | CB | Shoulder | Out |
| 2024 | 6 | Jimmie Ward | S | Groin | Out |
| 2024 | 6 | Robert Woods | WR | Foot | Out |
| 2024 | 6 | Derek Barnett | DE | Shoulder | Questionable |
| 2024 | 6 | Kurt Hinish | DT | Calf | Questionable |
| 2024 | 6 | Joe Mixon | RB | Ankle | Questionable |
| 2024 | 7 | Joe Mixon | RB | Ankle | — |
| 2024 | 7 | Del'Shawn Phillips | LB | Hip | — |
| 2024 | 7 | Laremy Tunsil | T | Ankle | — |
| 2024 | 7 | Azeez Al-Shaair | LB | Knee | Out |
| 2024 | 7 | Kamari Lassiter | CB | Shoulder | Out |
| 2024 | 7 | Henry To'oTo'o | LB | Concussion | Out |
| 2024 | 7 | Jimmie Ward | S | Groin | Out |
| 2024 | 7 | Robert Woods | WR | Foot | Out |
| 2024 | 7 | Steven Sims | WR | Back | Questionable |
| 2024 | 7 | Folorunso Fatukasi | DT | Shoulder | Questionable |
| 2024 | 8 | Will Anderson | DE | Chest | — |
| 2024 | 8 | Folorunso Fatukasi | DT | Shoulder | — |
| 2024 | 8 | Tytus Howard | T | Knee | — |
| 2024 | 8 | Kamari Lassiter | CB | Shoulder | — |
| 2024 | 8 | D'Angelo Ross | CB | Illness | — |
| 2024 | 8 | Steven Sims | WR | Back | — |
| 2024 | 8 | Laremy Tunsil | T | Ankle | — |
| 2024 | 8 | Robert Woods | WR | Foot | — |
| 2024 | 8 | Stefon Diggs | WR | Not injury related - resting player | — |
| 2024 | 8 | Azeez Al-Shaair | LB | Knee | Out |
| 2024 | 8 | Jimmie Ward | S | Groin | Out |
| 2024 | 8 | Henry To'oTo'o | LB | Concussion | Questionable |
| 2024 | 9 | Stefon Diggs | WR | Knee | — |
| 2024 | 9 | Calen Bullock | S | Shoulder | — |
| 2024 | 9 | Kamari Lassiter | CB | Shoulder | — |
| 2024 | 9 | Henry To'oTo'o | LB | Concussion | — |
| 2024 | 9 | Azeez Al-Shaair | LB | Knee | Out |
| 2024 | 9 | Jarrett Patterson | C | Concussion | Out |
| 2024 | 9 | Dameon Pierce | RB | Groin | Out |
| 2024 | 9 | Jimmie Ward | S | Groin | Out |
| 2024 | 10 | Denico Autry | DE | Not injury related - resting player | — |
| 2024 | 10 | Kenyon Green | G | Shoulder | — |
| 2024 | 10 | Azeez Al-Shaair | LB | Knee | — |
| 2024 | 10 | Derek Barnett | DE | Calf / Shoulder | — |
| 2024 | 10 | Dylan Horton | DE | Illness | — |
| 2024 | 10 | Shaquille Mason | G | Hip | — |
| 2024 | 10 | Jarrett Patterson | C | Concussion | — |
| 2024 | 10 | Jimmie Ward | S | Groin | — |
| 2024 | 10 | Laremy Tunsil | T | Not injury related - resting player | — |
| 2024 | 10 | Will Anderson | DE | Ankle | Out |
| 2024 | 10 | Dameon Pierce | RB | Groin | Out |
| 2024 | 10 | Folorunso Fatukasi | DT | Groin / Shoulder | Questionable |
| 2024 | 10 | Jake Hansen | LB | Ankle | Questionable |
| 2024 | 10 | Jerry Hughes | DE | Hip | Questionable |
| 2024 | 10 | Jeff Okudah | CB | Quadricep | Questionable |
| 2024 | 10 | Nico Collins | WR | Hamstring | Questionable |
| 2024 | 10 | Tank Dell | WR | Back | Questionable |
| 2024 | 11 | Denico Autry | DE | Not injury related - resting player | — |
| 2024 | 11 | Azeez Al-Shaair | LB | Knee | — |
| 2024 | 11 | Nico Collins | WR | Hamstring | — |
| 2024 | 11 | Jake Hansen | LB | Ankle | — |
| 2024 | 11 | Dylan Horton | DE | Shoulder | — |
| 2024 | 11 | Dameon Pierce | RB | Groin | — |
| 2024 | 11 | Derek Stingley | CB | Hip | — |
| 2024 | 11 | C.J. Stroud | QB | Right Hand | — |
| 2024 | 11 | Laremy Tunsil | T | Knee | — |
| 2024 | 11 | Will Anderson | DE | Ankle | Out |
| 2024 | 11 | Folorunso Fatukasi | DT | Foot | Out |
| 2024 | 11 | Blake Fisher | T | Concussion | Out |
| 2024 | 11 | Jeff Okudah | CB | Quadricep | Questionable |
| 2024 | 11 | Kamari Lassiter | CB | Concussion | Questionable |
| 2024 | 12 | Azeez Al-Shaair | LB | Knee | — |
| 2024 | 12 | Will Anderson | DE | Ankle | — |
| 2024 | 12 | Kamari Lassiter | CB | Concussion | — |
| 2024 | 12 | Derek Stingley | CB | Hip | — |
| 2024 | 12 | Folorunso Fatukasi | DT | Foot | Out |
| 2024 | 12 | Blake Fisher | T | Concussion | Out |
| 2024 | 12 | Denico Autry | DE | Knee / Oblique | Questionable |
| 2024 | 13 | Azeez Al-Shaair | LB | Knee | — |
| 2024 | 13 | Will Anderson | DE | Ankle | — |
| 2024 | 13 | Denico Autry | DE | Knee | — |
| 2024 | 13 | Blake Fisher | T | Concussion | — |
| 2024 | 13 | Jimmie Ward | S | Knee | — |
| 2024 | 13 | Nico Collins | WR | Not injury related - resting player | — |
| 2024 | 13 | Shaquille Mason | G | Not injury related - resting player | — |
| 2024 | 13 | Teagan Quitoriano | TE | Knee | — |
| 2024 | 13 | Laremy Tunsil | T | Not injury related - resting player | — |
| 2024 | 13 | Folorunso Fatukasi | DT | Foot | Out |
| 2024 | 13 | Jalen Pitre | S | Shoulder | Out |
| 2024 | 13 | Xavier Hutchinson | WR | Shoulder | Questionable |
| 2024 | 15 | Jalen Pitre | S | Shoulder | — |
| 2024 | 15 | Robert Woods | WR | Not injury related - personal matter | — |
| 2024 | 15 | Denico Autry | DE | Knee | — |
| 2024 | 15 | Folorunso Fatukasi | DT | Foot | — |
| 2024 | 15 | Xavier Hutchinson | WR | Shoulder | — |
| 2024 | 15 | Nico Collins | WR | Not injury related - resting player | — |
| 2024 | 15 | Joe Mixon | RB | Not injury related - resting player | — |
| 2024 | 15 | Laremy Tunsil | T | Not injury related - resting player | — |
| 2024 | 15 | Cade Stover | TE | Illness | Questionable |
| 2024 | 15 | Juice Scruggs | C | Foot | Out |
| 2024 | 15 | Nick Broeker | G | Hand | Questionable |
| 2024 | 15 | Kenyon Green | G | Shoulder | Questionable |
| 2024 | 15 | Christian Harris | LB | Calf | Questionable |
| 2024 | 15 | Jamal Hill | LB | Knee | Questionable |
| 2024 | 16 | Nick Broeker | G | Hand | — |
| 2024 | 16 | Kenyon Green | G | Shoulder | — |
| 2024 | 16 | Davis Mills | QB | Illness | — |
| 2024 | 16 | Del'Shawn Phillips | LB | Foot | — |
| 2024 | 16 | Joe Mixon | RB | Ankle | — |
| 2024 | 16 | Folorunso Fatukasi | DT | Ankle | Out |
| 2024 | 16 | John Metchie | WR | Shoulder | Out |
| 2024 | 16 | Juice Scruggs | C | Foot | Out |
| 2024 | 16 | Cade Stover | TE | Illness | Out |
| 2024 | 16 | Christian Harris | LB | Ankle | Questionable |
| 2024 | 17 | Tank Dell | WR | Knee | — |
| 2024 | 17 | Jimmie Ward | S | Foot | — |
| 2024 | 17 | Will Anderson | DE | Hand | — |
| 2024 | 17 | Nick Broeker | G | Hand | — |
| 2024 | 17 | Christian Harris | LB | Ankle | — |
| 2024 | 17 | John Metchie | WR | Shoulder | — |
| 2024 | 17 | Cade Stover | TE | Illness | — |
| 2024 | 17 | Folorunso Fatukasi | DT | Foot | Out |
| 2024 | 17 | Shaquille Mason | G | Knee | Out |
| 2024 | 17 | Juice Scruggs | C | Foot | Out |
| 2024 | 17 | Denico Autry | DE | Knee | Questionable |
| 2024 | 18 | Will Anderson | DE | Hand | — |
| 2024 | 18 | Nick Broeker | G | Hand | — |
| 2024 | 18 | Kamari Lassiter | CB | Quadricep | — |
| 2024 | 18 | Juice Scruggs | C | Foot | — |
| 2024 | 18 | Nico Collins | WR | Not injury related - resting player | — |
| 2024 | 18 | Joe Mixon | RB | Not injury related - resting player | — |
| 2024 | 18 | Laremy Tunsil | T | Not injury related - resting player | — |
| 2024 | 18 | Denico Autry | DE | Knee | Out |
| 2024 | 18 | Folorunso Fatukasi | DT | Ankle | Out |
| 2024 | 18 | Shaquille Mason | G | Knee | Out |
| 2024 | 18 | Jeff Okudah | CB | Concussion | Out |
| 2024 | 18 | Christian Harris | LB | Ankle | Questionable |
| 2024 | 18 | Jamal Hill | LB | Hamstring | Questionable |
| 2024 | 19 (WC) | Will Anderson | DE | Hand | — |
| 2024 | 19 (WC) | Denico Autry | DE | Knee | — |
| 2024 | 19 (WC) | Nick Broeker | G | Hand | — |
| 2024 | 19 (WC) | Folorunso Fatukasi | DT | Ankle | — |
| 2024 | 19 (WC) | Jake Hansen | LB | Ankle | — |
| 2024 | 19 (WC) | Christian Harris | LB | Ankle | — |
| 2024 | 19 (WC) | Jeff Okudah | CB | Concussion | — |
| 2024 | 19 (WC) | D'Angelo Ross | CB | Shoulder | — |
| 2024 | 19 (WC) | Shaquille Mason | G | Knee | Out |
| 2024 | 19 (WC) | John Metchie | WR | Shoulder | Questionable |
| 2024 | 19 (WC) | Teagan Quitoriano | TE | Calf | Questionable |
| 2024 | 20 (DIV) | Will Anderson | DE | Hand / Elbow | — |
| 2024 | 20 (DIV) | Denico Autry | DE | Knee | — |
| 2024 | 20 (DIV) | Nick Broeker | G | Hand | — |
| 2024 | 20 (DIV) | Shaquille Mason | G | Knee | — |
| 2024 | 20 (DIV) | Dalton Schultz | TE | Shoulder | — |
| 2024 | 20 (DIV) | Juice Scruggs | C | Ankle | — |
| 2024 | 20 (DIV) | Nico Collins | WR | Not injury related - resting player | — |
| 2024 | 20 (DIV) | Joe Mixon | RB | Ankle | Questionable |
| 2024 | 20 (DIV) | Robert Woods | WR | Hip | Questionable |
| 2024 | 20 (DIV) | Teagan Quitoriano | TE | Calf | Questionable |
| 2024 | 20 (DIV) | Azeez Al-Shaair | LB | Knee | Questionable |
| 2025 | 1 | Cam Robinson | T | Illness | — |
| 2025 | 1 | Braxton Berrios | WR | Hamstring | Out |
| 2025 | 1 | Christian Kirk | WR | Hamstring | Out |
| 2025 | 1 | Ed Ingram | G | Abdomen | Questionable |
| 2025 | 1 | Blake Fisher | T | Ankle | — |
| 2025 | 2 | Braxton Berrios | WR | Hamstring | Out |
| 2025 | 2 | Christian Kirk | WR | Hamstring | Out |
| 2025 | 2 | Ed Ingram | G | Abdomen | — |
| 2025 | 2 | Jake Andrews | C | Ankle | Out |
| 2025 | 2 | Blake Fisher | T | Ankle | — |
| 2025 | 3 | Braxton Berrios | WR | Hamstring | — |
| 2025 | 3 | Christian Kirk | WR | Hamstring | — |
| 2025 | 3 | Darrell Taylor | DE | Hip | — |
| 2025 | 3 | Jalen Pitre | S | Rib | — |
| 2025 | 3 | Jake Andrews | C | Ankle | — |
| 2025 | 3 | Kamari Lassiter | CB | Knee | — |
| 2025 | 3 | Jaylin Smith | CB | Hamstring | Out |
| 2025 | 4 | Tytus Howard | T | Illness | — |
| 2025 | 4 | Jakob Johnson | FB | Hamstring | — |
| 2025 | 4 | Nico Collins | WR | Knee | — |
| 2025 | 4 | Derek Stingley Jr. | CB | Oblique | Questionable |
| 2025 | 4 | Jake Andrews | C | Ankle | — |
| 2025 | 5 | Denico Autry | DE | Knee | Out |
| 2025 | 5 | Trent Brown | T | Not injury related - other | Out |
| 2025 | 5 | Foley Fatukasi | DT | Shoulder | Out |
| 2025 | 5 | Harrison Bryant | TE | Shoulder | — |
| 2025 | 5 | Nico Collins | WR | Knee | — |
| 2025 | 5 | Derek Stingley Jr. | CB | Oblique | — |
| 2025 | 5 | Will Anderson Jr. | DE | Not injury related - resting player | — |
| 2025 | 5 | Jaylen Reed | S | Knee | Out |
| 2025 | 7 | Denico Autry | DE | Knee | Questionable |
| 2025 | 7 | Tremon Smith | CB | Not injury related - personal matter | — |
| 2025 | 7 | Christian Kirk | WR | Hamstring | Out |
| 2025 | 7 | Jaylen Reed | S | Knee | Questionable |
| 2025 | 7 | Alijah Huzzie | CB | Knee | Out |
| 2025 | 8 | Denico Autry | DE | Knee | Questionable |
| 2025 | 8 | Derek Barnett | DE | Ankle | — |
| 2025 | 8 | Dalton Schultz | TE | Back / Shoulder | — |
| 2025 | 8 | Christian Kirk | WR | Hamstring | Out |
| 2025 | 8 | Darrell Taylor | DE | Illness | — |
| 2025 | 8 | Nico Collins | WR | Concussion | Out |
| 2025 | 8 | Brenden Bates | TE | Wrist | — |
| 2025 | 8 | Jaylin Smith | CB | Hamstring | Questionable |
| 2025 | 8 | Alijah Huzzie | CB | Knee | Out |
| 2025 | 9 | Denico Autry | DE | Knee | Questionable |
| 2025 | 9 | Laken Tomlinson | G | Not injury related - resting player | — |
| 2025 | 9 | Dalton Schultz | TE | Knee / Shoulder | Questionable |
| 2025 | 9 | Braxton Berrios | WR | Chest | — |
| 2025 | 9 | Christian Kirk | WR | Hamstring | — |
| 2025 | 9 | Jakob Johnson | FB | Hamstring | Out |
| 2025 | 9 | Nico Collins | WR | Concussion | — |
| 2025 | 9 | Jalen Pitre | S | Foot | — |
| 2025 | 9 | Dylan Horton | DE | Knee | Questionable |
| 2025 | 9 | Alijah Huzzie | CB | Knee | Out |
| 2025 | 9 | Woody Marks | RB | Calf | — |
| 2025 | 10 | Denico Autry | DE | Knee | — |
| 2025 | 10 | Ka'imi Fairbairn | K | Quadricep | Out |
| 2025 | 10 | Dalton Schultz | TE | Knee / Shoulder | — |
| 2025 | 10 | Braxton Berrios | WR | Chest | — |
| 2025 | 10 | Nick Chubb | RB | Foot | — |
| 2025 | 10 | Tytus Howard | T | Concussion | Out |
| 2025 | 10 | Jakob Johnson | FB | Hamstring | Out |
| 2025 | 10 | Harrison Bryant | TE | Shoulder | Questionable |
| 2025 | 10 | Jalen Pitre | S | Concussion | Out |
| 2025 | 10 | Dameon Pierce | RB | Not injury related - personal matter | — |
| 2025 | 10 | Christian Harris | LB | Shin | Out |
| 2025 | 10 | Ed Ingram | G | Knee | Out |
| 2025 | 10 | Dylan Horton | DE | Knee | — |
| 2025 | 10 | Will Anderson Jr. | DE | Quadricep | — |
| 2025 | 10 | C.J. Stroud | QB | Concussion | Out |
| 2025 | 11 | Denico Autry | DE | Knee | — |
| 2025 | 11 | Ka'imi Fairbairn | K | Quadricep | Out |
| 2025 | 11 | Dalton Schultz | TE | Shoulder / Illness | — |
| 2025 | 11 | Braxton Berrios | WR | Quadricep | — |
| 2025 | 11 | Azeez Al-Shaair | LB | Knee | — |
| 2025 | 11 | Tytus Howard | T | Concussion | — |
| 2025 | 11 | Jakob Johnson | FB | Hamstring | Questionable |
| 2025 | 11 | Harrison Bryant | TE | Neck / Shoulder | Out |
| 2025 | 11 | Damon Arnette | CB | Ankle | Out |
| 2025 | 11 | Davis Mills | QB | Elbow | — |
| 2025 | 11 | Jalen Pitre | S | Concussion | Out |
| 2025 | 11 | Jake Hansen | LB | Elbow | — |
| 2025 | 11 | Christian Harris | LB | Shin | — |
| 2025 | 11 | Ed Ingram | G | Knee | Questionable |
| 2025 | 11 | C.J. Stroud | QB | Concussion | Out |
| 2025 | 11 | Cade Stover | TE | Foot | Questionable |
| 2025 | 12 | Denico Autry | DE | Knee | — |
| 2025 | 12 | Trent Brown | T | Hand / Knee | — |
| 2025 | 12 | Ka'imi Fairbairn | K | Quadricep | — |
| 2025 | 12 | Dalton Schultz | TE | Shoulder | — |
| 2025 | 12 | Braxton Berrios | WR | Quadricep | — |
| 2025 | 12 | Azeez Al-Shaair | LB | Knee / Illness | — |
| 2025 | 12 | Tytus Howard | T | Ankle / Knee | — |
| 2025 | 12 | Myles Bryant | CB | Ankle | — |
| 2025 | 12 | Nico Collins | WR | Ankle | — |
| 2025 | 12 | Davis Mills | QB | Elbow | — |
| 2025 | 12 | Jalen Pitre | S | Concussion | Out |
| 2025 | 12 | Jake Hansen | LB | Elbow | — |
| 2025 | 12 | Ed Ingram | G | Knee | — |
| 2025 | 12 | Will Anderson Jr. | DE | Ankle | — |
| 2025 | 12 | C.J. Stroud | QB | Concussion | Out |
| 2025 | 12 | Cade Stover | TE | Foot | — |
| 2025 | 12 | Jamal Hill | LB | Hamstring | Out |
| 2025 | 13 | Denico Autry | DE | Knee | — |
| 2025 | 13 | Trent Brown | T | Hand | — |
| 2025 | 13 | Jalen Pitre | S | Concussion | — |
| 2025 | 13 | Will Anderson Jr. | DE | Chest | — |
| 2025 | 13 | C.J. Stroud | QB | Concussion | — |
| 2025 | 13 | Jamal Hill | LB | Hamstring | Out |
| 2025 | 13 | Blake Fisher | T | Illness | — |
| 2025 | 13 | Ajani Carter | CB | Hamstring | Out |
| 2025 | 14 | Denico Autry | DE | Knee | — |
| 2025 | 14 | Trent Brown | T | Hand | — |
| 2025 | 14 | Tim Settle | DT | Foot | — |
| 2025 | 14 | Azeez Al-Shaair | LB | Knee | — |
| 2025 | 14 | Will Anderson Jr. | DE | Chest / Shoulder | — |
| 2025 | 14 | Kamari Lassiter | CB | Foot | Questionable |
| 2025 | 14 | Jamal Hill | LB | Hamstring | Out |
| 2025 | 14 | Jaylen Reed | S | Forearm | Out |
| 2025 | 14 | Woody Marks | RB | Ankle | — |
| 2025 | 15 | Denico Autry | DE | Knee | — |
| 2025 | 15 | Trent Brown | T | Hand | — |
| 2025 | 15 | Sheldon Rankins | DT | Elbow / Shoulder | — |
| 2025 | 15 | Justin Watson | WR | Calf | Questionable |
| 2025 | 15 | Nick Chubb | RB | Ribs | Questionable |
| 2025 | 15 | E.J. Speed | LB | Knee | Questionable |
| 2025 | 15 | Azeez Al-Shaair | LB | Ankle | — |
| 2025 | 15 | Tytus Howard | T | Not injury related - personal matter | — |
| 2025 | 15 | Harrison Bryant | TE | Neck / Shoulder | Questionable |
| 2025 | 15 | Kamari Lassiter | CB | Foot | — |
| 2025 | 15 | Jamal Hill | LB | Hamstring | — |
| 2025 | 15 | Woody Marks | RB | Knee | — |
| 2025 | 16 | Denico Autry | DE | Knee | — |
| 2025 | 16 | Trent Brown | T | Hand | — |
| 2025 | 16 | Sheldon Rankins | DT | Knee | — |
| 2025 | 16 | Justin Watson | WR | Calf | Questionable |
| 2025 | 16 | Christian Kirk | WR | Illness | Questionable |
| 2025 | 16 | Nick Chubb | RB | Ribs | Questionable |
| 2025 | 16 | E.J. Speed | LB | Knee | — |
| 2025 | 16 | Azeez Al-Shaair | LB | Ankle / Knee | Questionable |
| 2025 | 16 | Darrell Taylor | DE | Ankle | Questionable |
| 2025 | 16 | Derek Stingley Jr. | CB | Oblique | Questionable |
| 2025 | 16 | Jake Hansen | LB | Chest | — |
| 2025 | 16 | Kamari Lassiter | CB | Foot | — |
| 2025 | 16 | Woody Marks | RB | Ankle | Questionable |
| 2025 | 17 | Denico Autry | DE | Knee | — |
| 2025 | 17 | Trent Brown | T | Ankle / Knee | Out |
| 2025 | 17 | Sheldon Rankins | DT | Knee | — |
| 2025 | 17 | Dalton Schultz | TE | Knee | — |
| 2025 | 17 | Justin Watson | WR | Calf | Out |
| 2025 | 17 | Azeez Al-Shaair | LB | Ankle / Knee | — |
| 2025 | 17 | Darrell Taylor | DE | Ankle | Out |
| 2025 | 17 | Derek Stingley Jr. | CB | Oblique | — |
| 2025 | 17 | Jake Hansen | LB | Chest | — |
| 2025 | 17 | Dylan Horton | DE | Hip | — |
| 2025 | 17 | Kamari Lassiter | CB | Foot / Knee | — |
| 2025 | 17 | Jamal Hill | LB | Wrist / Calf | Out |
| 2025 | 17 | Austin Brinkman | LS | Knee | — |
| 2025 | 17 | Woody Marks | RB | Ankle | — |
| 2025 | 17 | Aireontae Ersery | T | Thumb | Questionable |
| 2025 | 17 | Ajani Carter | CB | Hamstring | Out |
| 2025 | 18 | Denico Autry | DE | Knee | — |
| 2025 | 18 | Trent Brown | T | Ankle / Knee | Questionable |
| 2025 | 18 | Ka'imi Fairbairn | K | Illness | — |
| 2025 | 18 | Sheldon Rankins | DT | Elbow | — |
| 2025 | 18 | Dalton Schultz | TE | Not injury related - personal matter | — |
| 2025 | 18 | Azeez Al-Shaair | LB | Knee / Shoulder | — |
| 2025 | 18 | Darrell Taylor | DE | Ankle | Questionable |
| 2025 | 18 | Nico Collins | WR | Not injury related - resting player | — |
| 2025 | 18 | Derek Stingley Jr. | CB | Oblique | — |
| 2025 | 18 | Ed Ingram | G | Ankle | — |
| 2025 | 18 | Kamari Lassiter | CB | Ankle / Knee | Out |
| 2025 | 18 | Jamal Hill | LB | Calf | Out |
| 2025 | 18 | Austin Brinkman | LS | Knee | — |
| 2025 | 18 | Aireontae Ersery | T | Thumb | — |
| 2025 | 18 | Ajani Carter | CB | Hamstring | Questionable |
| 2025 | 19 (WC) | Denico Autry | DE | Knee | — |
| 2025 | 19 (WC) | Trent Brown | T | Ankle / Knee | — |
| 2025 | 19 (WC) | Sheldon Rankins | DT | Elbow | — |
| 2025 | 19 (WC) | Tytus Howard | T | Ankle | — |
| 2025 | 19 (WC) | Davis Mills | QB | Not injury related - personal matter | Questionable |
| 2025 | 19 (WC) | Derek Stingley Jr. | CB | Oblique | — |
| 2025 | 19 (WC) | Kamari Lassiter | CB | Ankle / Knee | — |
| 2025 | 19 (WC) | Jamal Hill | LB | Calf | — |
| 2025 | 19 (WC) | Jawhar Jordan | RB | Ankle | Out |
| 2025 | 19 (WC) | Jaylen Reed | S | Forearm | Questionable |
| 2025 | 19 (WC) | Austin Brinkman | LS | Knee | — |
| 2025 | 19 (WC) | Aireontae Ersery | T | Thumb | — |
| 2025 | 19 (WC) | Ajani Carter | CB | Hamstring | Out |
| 2025 | 20 (DIV) | Denico Autry | DE | Knee | — |
| 2025 | 20 (DIV) | Trent Brown | T | Ankle | Questionable |
| 2025 | 20 (DIV) | Sheldon Rankins | DT | Elbow | — |
| 2025 | 20 (DIV) | Justin Watson | WR | Concussion | Out |
| 2025 | 20 (DIV) | Azeez Al-Shaair | LB | Knee | — |
| 2025 | 20 (DIV) | Tytus Howard | T | Ankle | — |
| 2025 | 20 (DIV) | Nico Collins | WR | Concussion | Out |
| 2025 | 20 (DIV) | Ed Ingram | G | Shoulder | — |
| 2025 | 20 (DIV) | Kamari Lassiter | CB | Ankle / Knee | — |
| 2025 | 20 (DIV) | Jawhar Jordan | RB | Ankle | — |
| 2025 | 20 (DIV) | Jaylen Reed | S | Knee | — |
| 2025 | 20 (DIV) | Austin Brinkman | LS | Knee | — |
| 2025 | 20 (DIV) | Aireontae Ersery | T | Thumb | — |
| 2026 | 1 | Trent Brown | T | Wrist | — |
| 2026 | 1 | Will Anderson Jr. | DE | Not injury related - resting player | — |
| 2026 | 1 | Kayden McDonald | DT | Ankle | — |
| 2026 | 1 | Wade Woodaz | LB | Thumb | — |
| 2026 | 2 | Jadeveon Clowney | DE | Knee | Out |
| 2026 | 2 | Trent Brown | T | Hand / Wrist | — |
| 2026 | 2 | Dalton Schultz | TE | Not injury related - resting player | — |
| 2026 | 2 | Nico Collins | WR | Hamstring | Out |
| 2026 | 2 | Jacob Hummel | LB | Groin | Out |
| 2026 | 2 | Logan Hall | DE | Not injury related - resting player | — |
| 2026 | 2 | Ed Ingram | G | Groin | Out |
| 2026 | 2 | Will Anderson Jr. | DE | Not injury related - resting player | — |
| 2026 | 2 | Wade Woodaz | LB | Thumb | — |
| 2026 | 3 | Jadeveon Clowney | DE | Knee | Out |
| 2026 | 3 | Trent Brown | T | Knee / Wrist | Questionable |
| 2026 | 3 | M.J. Stewart | S | Knee | Out |
| 2026 | 3 | Dalton Schultz | TE | Not injury related - resting player | — |
| 2026 | 3 | Nico Collins | WR | Hamstring | Out |
| 2026 | 3 | Reed Blankenship | S | Thumb | — |
| 2026 | 3 | Jacob Hummel | LB | Groin | Out |
| 2026 | 3 | Logan Hall | DE | Knee | — |
| 2026 | 3 | Ed Ingram | G | Groin | Out |
| 2026 | 3 | Will Anderson Jr. | DE | Not injury related - resting player | — |
| 2026 | 3 | Wade Woodaz | LB | Thumb | — |
| 2026 | 4 | Jadeveon Clowney | DE | Knee | — |
| 2026 | 4 | Trent Brown | T | Illness / Knee | — |
| 2026 | 4 | M.J. Stewart | S | Knee | — |
| 2026 | 4 | Dalton Schultz | TE | Not injury related - resting player | — |
| 2026 | 4 | Azeez Al-Shaair | LB | Groin | — |
| 2026 | 4 | Nico Collins | WR | Hamstring | — |
| 2026 | 4 | Jake Hansen | LB | Calf | — |
| 2026 | 4 | Logan Hall | DE | Knee | — |
| 2026 | 4 | Ed Ingram | G | Groin | — |
| 2026 | 4 | Will Anderson Jr. | DE | Ankle | — |
| 2026 | 4 | British Brooks | RB | Hamstring | — |
| 2026 | 4 | Calen Bullock | S | Quadricep | — |
| 2026 | 4 | Wade Woodaz | LB | Ankle / Thumb | — |
| No results found. | |||||
Season History
| 2025 | Houston Texans | 12 | 5 | 0 | Lost Div | 404 | 295 | 109 | Ryans | |
| 2024 | Houston Texans | 10 | 7 | 0 | 1st of 4 | Lost Div | 372 | 372 | 0 | Ryans |
| 2023 | Houston Texans | 10 | 7 | 0 | 1st of 4 | Lost Div | 377 | 353 | 24 | Ryans |
| 2022 | Houston Texans | 3 | 13 | 1 | 4th of 4 | - | 289 | 420 | -131 | Smith |
| 2021 | Houston Texans | 4 | 13 | 0 | 3rd of 4 | - | 280 | 452 | -172 | Culley |
| 2020 | Houston Texans | 4 | 12 | 0 | 3rd of 4 | - | 384 | 464 | -80 | Crennel, O', Brien |
| 2019 | Houston Texans | 10 | 6 | 0 | 1st of 4 | Lost Div | 378 | 385 | -7 | O', Brien |
| 2018 | Houston Texans | 11 | 5 | 0 | 1st of 4 | Lost WC | 402 | 316 | 86 | O', Brien |
| 2017 | Houston Texans | 4 | 12 | 0 | 3rd of 4 | - | 338 | 436 | -98 | O', Brien |
| 2016 | Houston Texans | 9 | 7 | 0 | 1st of 4 | Lost Div | 279 | 328 | -49 | O', Brien |
| 2015 | Houston Texans | 9 | 7 | 0 | 1st of 4 | Lost WC | 339 | 313 | 26 | O', Brien |
| 2014 | Houston Texans | 9 | 7 | 0 | 2nd of 4 | - | 372 | 307 | 65 | O', Brien |
| 2013 | Houston Texans | 2 | 14 | 0 | 4th of 4 | - | 276 | 428 | -152 | Kubiak, Phillips |
| 2012 | Houston Texans | 12 | 4 | 0 | 1st of 4 | Lost Div | 416 | 331 | 85 | Kubiak |
| 2011 | Houston Texans | 10 | 6 | 0 | 1st of 4 | Lost Div | 381 | 278 | 103 | Kubiak |
| 2010 | Houston Texans | 6 | 10 | 0 | 3rd of 4 | - | 390 | 427 | -37 | Kubiak |
| 2009 | Houston Texans | 9 | 7 | 0 | 2nd of 4 | - | 388 | 333 | 55 | Kubiak |
| 2008 | Houston Texans | 8 | 8 | 0 | 3rd of 4 | - | 366 | 394 | -28 | Kubiak |
| 2007 | Houston Texans | 8 | 8 | 0 | 4th of 4 | - | 379 | 384 | -5 | Kubiak |
| 2006 | Houston Texans | 6 | 10 | 0 | 4th of 4 | - | 267 | 366 | -99 | Kubiak |
| 2005 | Houston Texans | 2 | 14 | 0 | 4th of 4 | - | 260 | 431 | -171 | Capers |
| 2004 | Houston Texans | 7 | 9 | 0 | 3rd of 4 | - | 309 | 339 | -30 | Capers |
| 2003 | Houston Texans | 5 | 11 | 0 | 4th of 4 | - | 255 | 380 | -125 | Capers |
| 2002 | Houston Texans | 4 | 12 | 0 | 4th of 4 | - | 213 | 356 | -143 | Capers |
| No results found. | ||||||||||
| Total | 0 | 0 | 0 | 0 | 0 | 0 | ||||
Draft History
Coach History
| DeMeco Ryans | 2023-2025 | 3 | 51 | 32 | 19 | 0 | .627 | 6 | 3 | 3 |
| Lovie Smith | 2022 | 1 | 17 | 3 | 13 | 1 | .206 | 0 | 0 | 0 |
| David Culley | 2021 | 1 | 17 | 4 | 13 | 0 | .235 | 0 | 0 | 0 |
| Bill O'Brien | 2014-2020 | 7 | 100 | 52 | 48 | 0 | .520 | 6 | 2 | 4 |
| Romeo Crennel | 2020 | 1 | 12 | 4 | 8 | 0 | .333 | 0 | 0 | 0 |
| Gary Kubiak | 2006-2013 | 8 | 125 | 61 | 64 | 0 | .488 | 4 | 2 | 2 |
| Wade Phillips | 2013 | 1 | 3 | 0 | 3 | 0 | .000 | 0 | 0 | 0 |
| Dom Capers | 2002-2005 | 4 | 64 | 18 | 46 | 0 | .281 | 0 | 0 | 0 |
| No results found. | ||||||||||
| Total | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
